Results 161 to 170 of about 283,997 (324)
Abstract Background Blood donor eligibility policies may exclude individuals based on medication use, but the donor health questionnaire may not reliably capture all prescriptions. This study evaluates the capacity of the compound adsorption device (CAD) within the INTERCEPT Blood System Pathogen Reduction Technology (PRT) for plasma to remove ...
Briana Greenwall +2 more
wiley +1 more source
Rapamycin limits CD4+ T cell proliferation in simian immunodeficiency virus–infected rhesus macaques on antiretroviral therapy [PDF]
Benjamin D Varco-Merth +42 more
openalex +1 more source
Abstract A mouse model of HIV‐associated atherosclerosis (Tg26+/−ApoE−/−) exhibited increased plaque area compared with the ApoE−/− mouse, linked to elevated indoleamine 2,3‐dioxygenase (IDO) activity. IDO catalyses the conversion of tryptophan (TRP) into kynurenine (KYN), measured by the KYN‐to‐TRP ratio.
Marcus V. S. Rangel +5 more
wiley +1 more source
ABSTRACT Kaposi Sarcoma (KS) is a rare vascular tumor linked to Human Herpesvirus‐8 (HHV‐8) infection, most often affecting immunocompromised patients with Human Immunodeficiency Virus/Acquired Immunodeficiency Syndrome (HIV/AIDS). Gastrointestinal KS (GI‐KS) is frequently underdiagnosed, particularly in resource‐limited settings, and may present with ...
Seyed Ali Safizadeh Shabestari +2 more
wiley +1 more source
Mitochondria‐associated membranes (MAMs) are contact sites between the endoplasmic reticulum and mitochondria that regulate calcium signaling, lipid metabolism, autophagy, and stress responses. This review outlines their molecular organization, roles in cellular homeostasis, and how dysfunction drives neurodegeneration, metabolic disease, cancer, and ...
Viet Bui +3 more
wiley +1 more source
Pharmacogenomics in clinical practice: Biomarker information in Brazilian drug labels
This review examines the PGx annotations in package inserts (bulas in Brazilian Portuguese) approved by ANVISA, the Brazilian Health Regulatory Agency, for 19 gene–drug pairs with strong or moderate recommendations for initial dosing alteration in the CPIC (Clinical Pharmacogenetic Implementation Consortion) guidelines and PGx testing required or ...
Guilherme Suarez‐Kurtz
wiley +1 more source
CD4:CD8 ratio and CD8+ cell count for prognosticating mortality in HIV-infected patients on antiretroviral therapy. [PDF]
Hoenigl, Martin, Jenks, Jeffrey Daniel
core +1 more source
Cotrimoxazole prophylaxis and antiretroviral therapy: an observational cohort study in China
Wei Cheng +8 more
openalex +1 more source

