Results 181 to 190 of about 259,590 (298)

2025 Consensus Clinical Management Guidelines for Niemann‐Pick Disease Type C

open access: yesJournal of Inherited Metabolic Disease, Volume 49, Issue 3, May 2026.
ABSTRACT In 2018, the International Niemann‐Pick Disease Alliance (INPDA) and the International Niemann‐Pick Disease Registry (INPDR) developed and published comprehensive clinical management guidelines to support inclusive and standardized care pathways in Niemann‐Pick disease type C (NPC)—an ultra‐rare, autosomal recessive, neurovisceral lysosomal ...
Tarekegn Hiwot   +33 more
wiley   +1 more source

Comparative Evaluation of the New HIV VIDAS® DUO AG/AB Assay With DUO Ultra on Well Characterized Participants From the HIV‐1 Acute Infection French ANRS PRIMO Cohort

open access: yesJournal of Medical Virology, Volume 98, Issue 5, May 2026.
ABSTRACT Diagnosing HIV‐1 infection as early as the primary infection is crucial. In this context, we performed a comparative evaluation and agreement analysis of the newly proposed serological assay for the combined detection of total antibodies against HIV and P24 antigen (HIV VIDAS® DUO AG/AB, bioMérieux®), with the previously available HIV VIDAS ...
Gilbert Mchantaf   +11 more
wiley   +1 more source

Factors Associated With Incomplete Adherence to Dolutegravir-Based Antiretroviral Therapy in Southwestern Uganda. [PDF]

open access: yesJ Acquir Immune Defic Syndr
Nutt CT   +16 more
europepmc   +1 more source

Discovery of 4‐Quinazolinone‐Containing Phenylalanine Derivatives as Potent, Resistant‐Tolerant HIV Capsid Inhibitors

open access: yesMedComm, Volume 7, Issue 5, May 2026.
Novel phenylalanine derivatives were identified as HIV‐1 capsid inhibitors. IC‐2i showed significant anti‐HIV‐1 activity at picomolar concentrations. ABSTRACT The HIV‐1 capsid (CA) is a validated antiviral target that plays critical roles in both the early and late stages of the viral life cycle.
Xujie Zhang   +18 more
wiley   +1 more source

Determinants of Cardiovascular Disease Risk Among LGBTQ+ Populations: A Systematic Review of Empirical Evidence

open access: yesNursing Open, Volume 13, Issue 5, May 2026.
ABSTRACT Background Understanding the multifactorial drivers of cardiovascular disease (CVD) risk in LGBTQ+ populations is critical to advancing equitable cardiovascular care. Objective To evaluate and synthesize empirical evidence on factors influencing CVD risk among sexual minority populations.
Sarinrut Sriprasong   +4 more
wiley   +1 more source

Interplay Between Oral Microbiota and Mouth Health in People Living With HIV Under Antiretroviral Therapy With or Without Periodontitis. [PDF]

open access: yesInt J Dent
Ramos Peña DE   +12 more
europepmc   +1 more source

Pharmacokinetics, Pharmacodynamics, Efficacy and Drug Resistance Selection of Injectable Long‐Acting Lenacapavir Pre‐Exposure Prophylaxis (PrEP) Against HIV

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 5, May 2026.
ABSTRACT Oral pre‐exposure prophylaxis (PrEP) can substantially reduce HIV infection risk when taken as prescribed. However, many individuals struggle adhering to the daily regimen. Twice‐yearly injections of the novel HIV capsid inhibitor lenacapavir (LEN) demonstrated potential in recent PrEP trials.
Hee‐yeong Kim   +3 more
wiley   +1 more source

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