Results 161 to 170 of about 2,509,923 (294)

Safety and Immunogenicity of BNT162b2 in Antiretroviral Therapy-Treated People With HIV. [PDF]

Open Forum Infect Dis
Mitha E, Berhe M, Aberg J, Lucasti CJ, Chalhoub F, Kitchin N, Vogler I, Lockhart SP, Fuchs S, Quandt J, Gruber WC, Webber C, Kühnle MC, Muik A, Lui BG, Vehreschild MJGT, Stephan C, Bushway M, Xu X, Belanger TJ, Trammel Price J, Liebscher S, Bailey R, Mather S, Adams EM, Shpyro S, Lagkadinou E, Türeci Ö, Swanson KA, Şahin U, Gurtman A.   +30 more
europepmc   +1 more source

HIV incidence and correlates of incident infection among Brazilian blood donors following adoption of individual donor assessment

Vox Sanguinis, EarlyView.
Abstract Background and Objectives In 2020, Brazil implemented individual donor assessment (IDA), expanding eligibility to include individuals previously deferred, such as men who have sex with men (MSM). We assessed human immunodeficiency virus (HIV) incidence and correlates of incident infection among blood donors following this policy change ...
Renata Buccheri, Eduard Grebe, Donald E. Warden, Carolina Miranda, Ligia Capuani, Cecilia S. Alencar, Luiz Amorim, Cesar de Almeida‐Neto, Maisa Ribeiro, Paula Loureiro, Nelson Fraiji, Clara Di Germanio, Leilani Montalvo, Jennifer Leddy, Mars Stone, Ester C. Sabino, Brian Custer, the Recipient Epidemiology and Donor Evaluation Study‐IV‐Pediatric (REDS‐IV‐P)   +17 more
wiley   +1 more source

Physiological and anatomical determinants of placental drug transfer

The Journal of Physiology, EarlyView.
Abstract figure legend Fetal exposure to pharmaceuticals and their subsequent clearance back to the maternal circulation are governed by placental transfer. Passive diffusion down a maternal‐to‐fetal concentration gradient is the primary route of fetal drug exposure, with specific compounds undergoing transporter‐mediated transfer.
Rohan M. Lewis, Anandita Umapathy, Jane K. Cleal, Bram G. Sengers   +3 more
wiley   +1 more source

Improvement in Aortic Stiffness After 9 Months of Antiretroviral Therapy in Treatment-Naïve People Living with HIV. [PDF]

Diagnostics (Basel)
Robbertse PS, Doubell AF, Ackermann C, Maposa I, Herbst PG.   +4 more
europepmc   +1 more source

Virus‐specific alterations in placental structure and transporter expression following maternal arbovirus infection

The Journal of Physiology, EarlyView.
Abstract figure legend Arboviruses induce virus‐specific alterations in placental structure and functional markers. Chikungunya virus (CHIKV) exposure was associated with reduced syncytiotrophoblast and syncytial knot areas, increased cytotrophoblast proliferation (Ki‐67) and thyroid transporter (MCT8) expression, reduced protective (P‐gp and BCRP ...
Cherley B. V. Andrade, Enrrico Bloise, Natália L. Silva, Jair R. S. Braga, Sharton V. A. Coelho, Veronica M. O. Nascimento, Guinever E. Imperio, Camila O. S. Nunes, Antônio J. L. A. Cunha, Marcelo A. Pascoal‐Xavier, Luciana B. Arruda, Arnaldo Prata‐Barbosa, Kristin L. Connor, Tania M. Ortiga‐Carvalho   +13 more
wiley   +1 more source

HIV epidemic in Lesotho - HIV treatment and monitoring of patients on antiretroviral therapy 2014-2024. [PDF]

PLOS Glob Public Health
Moshoeshoe S, Motebang M, Mokhesi K, Ts'oeu M, Ramphalla P, Mengistu Y, Lecher S.   +6 more
europepmc   +1 more source

Brain viral reservoir seeding and neurological metabolic dysregulation in early‐life immunodeficiency virus infection

Brain Pathology, Volume 36, Issue 6, November 2026.
Brain viral reservoirs were undetectable in neonatal SIV during the first 3 days post infection; antiretroviral therapy (ART) at 3 dpi prevented brain reservoir seeding and normalized metabolic function, highlighting the necessity of very early treatment to protect the developing CNS.
Li Ma, Robert Blair, Yao‐Zhong Liu, Xiaolei Wang, Eunice Vincent, Christopher Yu, Lara A. Doyle‐Meyers, Cissy Zhang, Ahmad Saied, Anne Le, Ronald S. Veazey, Qigui Yu, Huanbin Xu   +12 more
wiley   +1 more source

Tuberculosis after Preventive Therapy in Persons Living with HIV Initiating Antiretroviral Therapy. [PDF]

Emerg Infect Dis
Chen Q.
europepmc   +1 more source

Evaluating Harm Reduction Advice From Large Language Models

Drug and Alcohol Review, Volume 45, Issue 7, November 2026.
ABSTRACT Introduction Large language models (LLM) and generative Artificial Intelligence are increasingly providing health information. We have applied a novel method to evaluate the harm reduction information generated by popular LLMs. We focused on the filtration of oral medications for injection and the availability of local harm reduction services.
Khy Choo, Nathan Smith, Bernadette Ward, Robert M. Lundin   +3 more
wiley   +1 more source

Medicinal Chemistry Aspects of Thiazole and Thiazolidine Derivatives as Fundamental Building Blocks to Design New NNRTIs Against HIV‐1 Reverse Transcriptase

ChemMedChem, Volume 21, Issue 19, 14 October 2026.
HIV‐1 reverse transcriptase (HIV‐1 RT) is a polymerase enzyme and a key target in HIV‐1 therapy. The discovery of selective HIV‐1 RT inhibitors has highlighted thiazole scaffolds and their derivatives, thiazolidine‐2‐one and thiazolidine‐2,4‐dione, as promising structures for the rational design of novel non‐nucleoside reverse transcriptase inhibitors (
José Arion da Silva Moura, Matheus Vinicius Guimarães de Melo, Diane Regis Santos do Nascimento, Thaynara Paula Warren Bezerra, Mathieu Métifiot, Patricia Recordon‐Pinson, Maira Galdino da Rocha Pitta, Marina Galdino da Rocha Pitta, Michelly Cristiny Pereira, Marie‐Line Andreola   +9 more
wiley   +1 more source