Results 191 to 200 of about 259,590 (298)

Tuberculosis after TB Preventive Therapy in Persons Living with HIV Recently Initiating Antiretroviral Therapy, Mozambique. [PDF]

Emerg Infect Dis
Templin L, Varajidas Y, Respeito D, Zindoga P, Weiss D, Nguimfack A, Filipe E, Mahumane A, de Deus MIT, Mizela J, Chilundo S, Simoes B, Couto A, Pathmanathan I, Dirlikov E, José B.   +15 more
europepmc   +1 more source

Proportional Hazards Regression for Interval‐Censored Outcomes With an Interval‐Censored Covariate

Statistics in Medicine, Volume 45, Issue 10-12, May 2026.
ABSTRACT Identifying predictors for viral rebound trajectories after antiretroviral therapy (ART) interruption is central to HIV cure research. Motivated by the need to determine whether the time to achieve viral suppression after ART initiation can predict the time to viral rebound following ART interruption, we investigate modeling approaches that ...
Dongdong Li, Yue Song, Wenbin Lu, Huldrych F. Günthard, Roger Kouyos, Rui Wang   +5 more
wiley   +1 more source

How should APOBEC3-induced resistance mutations be considered in the management of antiretroviral therapy? [PDF]

J Antimicrob Chemother
Gilbert M, Ferré VM, Guilbaud R, Digumber M, Peytavin G, Damond F, Le Hingrat Q, Yazdanpanah Y, Descamps D, Charpentier C, Joly V, Ghosn J.   +11 more
europepmc   +1 more source

A Bourdieusian Approach to the Demobilisation of Brazil's AIDS Movement

Sociology of Health &Illness, Volume 48, Issue 4, May 2026.
ABSTRACT This article offers a Bourdieusian analysis of the demobilization of Brazil's AIDS movement, once a globally celebrated force in shaping innovative, rights‐based public health responses. Drawing on extensive qualitative data, I argue that the movement's decline cannot be explained solely by institutional co‐optation, biomedicalisation, or ...
Helena de Moraes Achcar
wiley   +1 more source

CCR5Δ32 polymorphism is associated with increased central memory CD4+ T cells in virologically suppressed people living with HIV on antiretroviral therapy. [PDF]

Med Microbiol Immunol
Lopes-Araujo HF, Carvalho-Silva WHV, Andrade-Santos JL, Guedes MCS, Souto FO, De Alencar LCA, Brennand IBLPB, Monteiro TKO, Feliciano-Santos K, Chies JAB, Guimarães RL.   +10 more
europepmc   +1 more source

The association of methadone use with physical function and frailty among persons who inject drugs

Addiction, Volume 121, Issue 5, Page 1217-1226, May 2026.
Abstract Background and Aims Persons who inject drugs (PWID) experience a high burden of early‐onset frailty, primarily due to multifactorial causes such as infections (human immunodeficiency virus [HIV], hepatitis C virus [HCV]), substance use, and polypharmacy.
Grace L. Kulik, Hsing‐Yu Hsu, Jacqueline Rudolph, Yutong Jiang, Kristine M. Erlandson, Damani A. Piggott, Shruti Mehta, Jeremy D. Walston, Gregory Kirk, Todd T. Brown, Jing Sun   +10 more
wiley   +1 more source

Survival and predictors of mortality among people living with HIV (PLHIV) on antiretroviral therapy in Ethiopia (2016-2023): a retrospective cohort study. [PDF]

BMJ Open
Amogne MD, Kebede A, Asfaw D, Fetensa G, Lemessa F, Zealiyas K, Belihu WB, Tamene W, Gudeta G, Wariso FB, Hailu G, Shiferaw AY, Debel L, Dechassa W, Bejiga B, Itefa K, Hailemariam BW, Habtesilase A, Yenealem D, Bekuma TT, Bulti J, Tollera G, Tadesse G.   +22 more
europepmc   +1 more source

Microglial reactivity and nodule formation are associated with Synaptodendritic damage in the brains of people with HIV‐1

Brain Pathology, Volume 36, Issue 3, May 2026.
Despite effective ART, neurocognitive impairment persists in people with HIV. Brains from PWH present exacerbated microgliosis and formation of microglial nodules that are actively engaged in neuronal phagocytosis, resulting in neuronal injury and dendritic loss.
Roberta S. Dos Reis, Lauren A. Ignatz, Sathish Selvam, Marc C. E. Wagner, Sara Gianella, Antoine Chaillon, Vanessa Gomez‐Moreno, Jeremy Martison, Leah H. Rubin, Sabina Heberlen, Valentina Stosor, Jordan Lake, Velpandi Ayyavoo   +12 more
wiley   +1 more source

Optimizing Oligonucleotide Therapeutics: A Model‐Informed Drug Development Perspective

Clinical and Translational Science, Volume 19, Issue 5, May 2026.
ABSTRACT Oligonucleotide therapies have emerged as a powerful therapeutic class, providing novel solutions for diverse diseases through antisense oligonucleotides (ASOs), small interfering RNAs (siRNAs), and aptamers that specifically target and modulate gene expression or protein function. However, oligonucleotide development faces distinct challenges,
Ye Yuan, Vishnu Sharma, Venkatesh Atul Bhattaram, Xiaolei Pan, Justin Earp, Yun Wang, Jiang Liu, Hao Zhu   +7 more
wiley   +1 more source

HIV-1 drug resistance and associated risk factors in patients with antiretroviral therapy failure in Chongqing, China, 2019-2023. [PDF]

PLoS One
Zhang H, Wu P, Ye W.
europepmc   +1 more source