Results 191 to 200 of about 4,576,038 (327)

Factors Influencing the Binding of HIV‐1 Protease Inhibitors: Insights from Machine Learning Models

ChemMedChem, Volume 20, Issue 15, August 2, 2025.
Machine learning unlocks the secrets of HIV‐1 protease inhibition, paving the way for data‐driven antiviral drug design. This study analyzes crystallographic data from hundreds of protein–ligand complexes, predicting ligand binding affinity with over 85% accuracy.
Yaffa Shalit, Inbal Tuvi‐Arad
wiley   +1 more source

Immune Reconstitution after 2 Years of Successful Potent Antiretroviral Therapy in Previously Untreated Human Immunodeficiency Virus Type 1–Infected Adults [PDF]

, 1999
Daan W. Notermans, Nadine G. Pakker, Dörte Hamann, Norbert A. Foudraine, Robert H. Kauffmann, Pieter L. Meenhorst, Jaap Goudsmit, Marijke Roos, P T Schellekens, Frank Miedema, Sven A. Danner   +10 more
openalex   +1 more source

Do we need routine integrase resistance testing before starting antiretroviral therapy? [PDF]

Lancet HIV
Kantor R, Pau AK, Kozal MJ, Hyle EP.
europepmc   +1 more source

Generation of Neural Organoids and Their Application in Disease Modeling and Regenerative Medicine

Advanced Science, Volume 12, Issue 29, August 7, 2025.
Neural organoids provide a versatile platform for neurological research. Advances in organoid technology have partially achieved human neural tissue complexity in terms of tissue structure, cell diversity, and neural signaling, offering insights into neural disorders and regenerative strategies. Technology advances from biomaterials, bio‐manufacturing,
Ruiqi Huang, Feng Gao, Liqun Yu, Haokun Chen, Rongrong Zhu   +4 more
wiley   +1 more source

Acceptability of long acting injectable antiretroviral therapy in people living with HIV at a large single centre. [PDF]

Sci Rep
Arsuffi S, Mazzi C, Calza S, Colombo FR, Minisci D, Fioretti B, Izzo I, Polesini I, Anzoni C, Castelli F, Quiros-Roldan E, Focà E.   +11 more
europepmc   +1 more source

Activated Memory CD4 ⁺ T Helper Cells Repopulate the Intestine Early following Antiretroviral Therapy of Simian Immunodeficiency Virus-Infected Rhesus Macaques but Exhibit a Decreased Potential To Produce Interleukin-2

, 1999
Joseph J. Mattapallil, Zeljka Smit‐McBride, Peter J. Dailey, Satya Dandekar   +3 more
openalex   +1 more source

Fast pH‐Driven Solubilization Method of Realgar (As4S4) to Reduce the Toxicity of Arsenic [As(III)] for Medicinal Purposes

Advanced Science, Volume 12, Issue 29, August 7, 2025.
Arsenic trioxide transformed acute promyelocytic leukemia therapy and shows promise against HIV. A new method to solubilize the mineral realgar produces different arsenic species depleting the main arsenic target, nuclear PML protein, and retaining effects on leukemic and HIV reservoir cells, while minimizing off‐target damage.
Bojana Lucic, Douglas Santana Franciscato, Helton Pereira Nogueira, Lara Gallucci, Alceu Totti Silveira Junior, Asmaa Mohamed Ismail, Millie Robinson, Teresa Dallinger, Claudia Gutfleisch, Jochen Kurz, Maytê Toledo, Jessica Dias da Silva Ferraz, Mohammad Tarek, Danilo Dias, Ricardo Sobhie Diaz, Mahmoud ElHefnawi, Mattia Forcato, Hugo P Monteiro, Marina Lusic, Iart Luca Shytaj, Andrea Savarino   +20 more
wiley   +1 more source

Diabetes mellitus in patients with HIV naïve to antiretroviral therapy initiating integrase inhibitors therapy. [PDF]

Sci Rep
Dias da Costa S, Bichança E, Cruz F, Guimarães AR, Piñeiro C, Santos-Sousa H, Serrão R, Freitas P.   +7 more
europepmc   +1 more source

Effect of potent antiretroviral therapy on recurrent cytomegalovirus retinitis treated with the ganciclovir implant [PDF]

, 1999
Janet L. Davis, Homayoun Tabandeh, William J. Feuer, Seema Kumbhat, Daniel B. Roth, Nauman Chaudhry   +5 more
openalex   +1 more source

Toward information resilience: Applying intersectionality to the HIV/AIDS information practices of Black sexual minority men

Journal of the Association for Information Science and Technology, Volume 76, Issue 8, Page 1123-1140, August 2025.
Abstract Using intersectionality as a critical theoretical framework and analytical tool, this study investigated the HIV/AIDS information practices of Black sexual minority men (SMM). Twenty‐two Black SMM were interviewed about their HIV/AIDS‐related information practices.
Megan Threats
wiley   +1 more source