Results 241 to 250 of about 2,509,923 (294)
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Medical Clinics of North America, 1996
Advances in knowledge of the pathogenesis of HIV infection, coupled with the arrival of new antiviral agents and results from clinical trials, have moved clinicians closer to effective therapy of HIV infection. Despite these advances, many important issues remain unresolved.
S C, Threlkeld, M S, Hirsch
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Advances in knowledge of the pathogenesis of HIV infection, coupled with the arrival of new antiviral agents and results from clinical trials, have moved clinicians closer to effective therapy of HIV infection. Despite these advances, many important issues remain unresolved.
S C, Threlkeld, M S, Hirsch
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Intensification of Antiretroviral Therapy
AIDS Research and Human Retroviruses, 2001ALTHOUGH IMPORTANT DEVELOPMENTS in antiretroviral treatment have occurred, the ability to durably suppress HIV replication is still quite limited. Current guidelines recommend the introduction of at least two compounds not included in the discontinued regimen for treatment failures.1–3 This approach is based on the assumption that resistance mutations ...
M, Núñez +2 more
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Tropical Doctor, 2006
With the expansion and convergence of the HIV and TB epidemics worldwide, clinicians will increasingly will be called to manage and treat co-infected patients. TB and HIV medications have overlapping and additive toxicities that can complicate therapy.
Swaminathan, Soumya +5 more
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With the expansion and convergence of the HIV and TB epidemics worldwide, clinicians will increasingly will be called to manage and treat co-infected patients. TB and HIV medications have overlapping and additive toxicities that can complicate therapy.
Swaminathan, Soumya +5 more
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Infectious Disease Clinics of North America, 2014 In this article, the scientific evidence and professional guidelines regarding the timing of antiretroviral therapy initiation are reviewed, with discussion of the increasingly persuasive evidence in favor of starting treatment early in the course of human immunodeficiency virus disease.
Alice K Pau
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Advances in antiretroviral therapy
Current Opinion in HIV and AIDS, 2013To review recent data about advances in ART.In the last 2 years, clinical trials have demonstrated the safety and efficacy of three integrase transfer inhibitors [raltegravir (RAL), elvitegravir (EVG) and dolutegravir (DTG)], one new nonnucleoside reverse transcriptase inhibitor [rilpivirine (RIL)] and a new extended release formulation of nevirapine ...
Jose R, Arribas, Joseph, Eron
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Clinics in Podiatric Medicine and Surgery, 1998
The use of a combination of more potent antiretroviral agents has resulted in suppression of HIV replication to undetectable levels in many patients. Three classes of antiretroviral drugs are currently available: nucleoside reverse transcriptase inhibitors, nonnucleoside reverse transcriptase inhibitors, and protease inhibitors.
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The use of a combination of more potent antiretroviral agents has resulted in suppression of HIV replication to undetectable levels in many patients. Three classes of antiretroviral drugs are currently available: nucleoside reverse transcriptase inhibitors, nonnucleoside reverse transcriptase inhibitors, and protease inhibitors.
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Antiretroviral Therapy With Heart
American Journal of Therapeutics, 2009Antiretroviral therapy (ART) has resulted in a substantial improvement in the morbidity and mortality associated with human immunodeficiency virus (HIV) infection. As this population ages, cardiovascular disease is becoming an increasingly important health burden.
Paul, Randell, Graeme, Moyle
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Journal of the American Academy of Dermatology, 1989
Research into the biology of human immunodeficiency virus type 1 (HIV-1), the causative agent of the acquired immunodeficiency syndrome, has yielded valuable information about the replicative cycle of the virus. The steps involved are (1) attachment of the virus to a receptor protein on the surface of the target cell, (2) entry of the virus into the ...
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Research into the biology of human immunodeficiency virus type 1 (HIV-1), the causative agent of the acquired immunodeficiency syndrome, has yielded valuable information about the replicative cycle of the virus. The steps involved are (1) attachment of the virus to a receptor protein on the surface of the target cell, (2) entry of the virus into the ...
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Pediatric antiretroviral therapy
Expert Review of Anti-infective Therapy, 2010The rate of perinatal HIV transmission has decreased significantly in developed countries. However, worldwide, it remains the main source of HIV infection within the pediatric population. Recent advances as a result of findings from clinical trials, viral resistance testing and the advent of new drugs have increased the options for initial treatment ...
Adriana, Cadilla +2 more
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Pharmacogenetics of antiretroviral therapy
Expert Opinion on Drug Metabolism & Toxicology, 2014Human genetic testing is rapidly entering into most medical disciplines, mainly as a way to predict hereditary conditions including predisposition to cancers or degenerative diseases. Another area of interest for human genomics is to ascertain the therapeutic effect and prevent potential toxicities and/or drug-drug interactions of medication.Several ...
Pablo, Barreiro +4 more
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