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Pediatric Antiretroviral Therapy
2019Human immunodeficiency virus (HIV) is one of the most serious pediatric infectious diseases, affecting around 3 million children and adolescents worldwide. Lifelong antiretroviral treatment (ART) provides multiple benefits including sustained virologic suppression, restoration and preservation of immune function, decreased morbidity and mortality, and ...
Wei Li A Koay +2 more
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Combination antiretroviral therapy
Expert Opinion on Pharmacotherapy, 2011Combination antiretroviral therapy (cART) was one of the greatest achievements in medicine in the twentieth century. It has rapidly evolved during the last 10 years from suboptimal monotherapy to an effective triple therapy that can change the natural history of HIV-1 infection from a deadly disease to a chronic, manageable condition.
Pere Domingo, Francesc Vidal
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Adhering to Antiretroviral Therapies
AIDS Patient Care and STDs, 2001In 1999, the AIDS program conducted a survey of more than 1,000 patients in Sao Paulo [Brazil]. It found that 69 percent achieved 80 percent adherence, which means they took their medicine properly 80 percent of the time. According to Margaret Chesney, a professor of medicine at the University of California at San Francisco who studies behavioral ...
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Overview of Antiretroviral Therapy
Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 1994All of the agents that are available for the treatment of human immunodeficiency viral infection belong to the class of drugs called nucleoside analogs that act on the virus's reverse transcriptase enzyme. As their use expanded for increasing cohorts of patients and stages of disease, it became clear that additional agents were required that would act ...
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Complications of antiretroviral therapy
Archives of Ibadan Medicine, 2005No Abstract Available Archives of Ibadan Medicine Vol.5(1&2) 2004: 52 ...
Omobosola Akinsete, Keith Henry
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Antiretroviral therapy for children
Acta Paediatrica, 1994Advances in the development of antiviral drugs have been rapid and dramatic. Since the recognition of HIV‐1 as the cause of AIDS in 1984, and improved understanding of retroviral replication and pathogenesis, three antiviral drugs, Zidovudine, Didanosine, and Zalcitabine, have been developed to the point of routine use in humans.
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Paronychia associated with antiretroviral therapy
British Journal of Dermatology, 1999We report six HIV patients who developed painful periungual inflammation of several nails during treatment with the antiretroviral drugs indinavir and lamivudine. The lesions appeared 2-12 months after starting treatment. The occurrence of paronychia in HIV patients has recently been reported in two groups of patients receiving either indinavir or ...
Tosti A. +4 more
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Initiation of antiretroviral therapy
Current Opinion in Internal Medicine, 2006Until there is a therapy or a vaccine that can eradicate HIV infection, it is important to continue debating the issues of when and how to use the many antiviral agents licensed as initial treatment since there remain many areas of uncertainty.Early initiation of treatment may be beneficial in terms of HIV progression but it has to be weighed against ...
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UPDATE ON ANTIRETROVIRAL THERAPY
Radiologic Clinics of North America, 1997The availability of 11 antiretroviral agents has greatly expanded options in the treatment of HIV-infected patients. Newer treatment strategies using combination therapy have significantly improved outcomes for patients with all stages of infection.
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