Results 51 to 60 of about 139,558 (270)

Use of antiretroviral therapy in households and risk of HIV acquisition in rural KwaZulu-Natal, South Africa, 2004–12: a prospective cohort study

The Lancet Global Health, 2014
Background: Studies of HIV-serodiscordant couples in stable sexual relationships have provided convincing evidence that antiretroviral therapy can prevent the transmission of HIV.
Alain Vandormael, MS, Prof. Marie-Louise Newell, PhD, Till Bärnighausen, MD, Prof. Frank Tanser, PhD   +3 more
doaj   +1 more source

Factors Influencing the Binding of HIV‐1 Protease Inhibitors: Insights from Machine Learning Models

ChemMedChem, Accepted Article.
HIV‐1 protease inhibitors are crucial for antiviral therapies targeting acquired immunodeficiency syndrome (AIDS). Hundreds of HIV‐1 protease complexes with various ligands have been resolved and deposited in the Protein Data Bank. However, binding affinity measurements for these ligands are not always available.
Yaffa Shalit, Inbal Tuvi-Arad
wiley   +1 more source

Hematological parameters abnormalities and associated factors in HIV-positive adults before and after highly active antiretroviral treatment in Goba Referral Hospital, southeast Ethiopia: A cross-sectional study

SAGE Open Medicine, 2021
Objectives: Hematological abnormalities of the major blood cell lines are frequently reported in patients with HIV-1 infection, in patients without antiretroviral therapy, and during the advanced stages of the disease.
Negesso Duguma, Girum Tesfaye Kiya, Wondimagegn Adissu Maleko, Lealem Gedefaw Bimerew   +3 more
doaj   +1 more source

Antitumour effects of antiretroviral therapy [PDF]

Nature Reviews Cancer, 2004
Infection by human immunodeficiency virus (HIV) is associated with an increased risk of certain tumours, particularly Kaposi's sarcoma, non-Hodgkin's lymphomas and cervical cancer. However, the incidence of these tumours in HIV-infected patients has decreased significantly since the widespread use of highly active antiretroviral therapy (HAART).
Monini, P, Sgadari, C, Toschi,E, BARILLARI, GIOVANNI, Ensoli, B.   +4 more
openaire   +5 more sources

A Randomized Phase 1 Study Evaluating Pharmacokinetics, Safety, and Tolerability of a High‐Concentration, Long‐Acting Cabotegravir Formulation in Adults Without HIV

Clinical Pharmacology in Drug Development, EarlyView.
Abstract Long‐acting (LA) cabotegravir 200‐mg/mL (CAB200) injections are approved for HIV‐1 prevention and as a complete LA HIV‐1 treatment regimen with rilpivirine. A high‐concentration suspension formulation, cabotegravir 400 mg/mL (CAB400‐D), was developed to enable less frequent dosing and self‐administration. This phase 1, double‐blind, randomized
Kelong Han, Paul Benn, Jörg Sievers, David Dorey, Michael Warwick‐Sanders, Randa Hareedy, Louise Harkness, Claudia Leemereise, Kjersten Offenbecker, Christina Donatti, Darin B. Brimhall, Christian Schwabe, Craig Boyle, Michael A. Hassman, Steve Knowles, Ronald D'Amico, William R. Spreen   +16 more
wiley   +1 more source

A literature review on cardiovascular risk in human immunodeficiency virus-infected patients: implications for clinical management

Brazilian Journal of Infectious Diseases
INTRODUCTION: In recent years, there has been growing concern about an increasing rate of cardiovascular diseases in human immunodeficiency virus-infected patients, which could be associated with side effects of highly active antiretroviral therapy.
Mansueto Gomes Neto, Ricardo Zwirtes, Carlos Brites   +2 more
doaj   +1 more source

Crusted scabies-associated immune reconstitution inflammatory syndrome

BMC Infectious Diseases, 2012
Background Despite the widely accepted association between crusted scabies and human immunodeficiency virus (HIV)-infection, crusted scabies has not been included in the spectrum of infections associated with immune reconstitution inflammatory syndrome ...
Fernández-Sánchez Mónica, Saeb-Lima Marcela, Alvarado-de la Barrera Claudia, Reyes-Terán Gustavo   +3 more
doaj   +1 more source

Adhering to antiretroviral therapy: A qualitative analysis of motivations for and obstacles to consistent use of antiretroviral therapy in people living with HIV

SAGE Open Medicine, 2020
Objectives: Based on the 2015 U.S. Centers for Disease Control and Prevention data, 40% of people living with HIV in the United States with an HIV diagnosis and 18.5% of people living with HIV in HIV care in the United States are not virally suppressed ...
Lisa Fleischer, Ann Avery
doaj   +1 more source

Cancer incidence in people with HIV in Italy: Comparison of the ICONA COHORT with general population data

International Journal of Cancer, EarlyView.
What's New? Immune suppression induced by HIV infection significantly increases the risk of certain cancers among people with HIV (PWH). In the present study, the authors investigated cancer incidence among HIV‐infected individuals in Italy using data from the Italian Cohort Naïve Antiretrovirals. Comparison with the corresponding general population in
Pierluca Piselli, Alessandro Tavelli, Claudia Cimaglia, Camilla Muccini, Alessandra Bandera, Giulia C. Marchetti, Carlo Torti, Valentina Mazzotta, Luca Pipitò, Alessandro Caioli, Enrico Girardi, Andrea Antinori, Diego Serraino, Antonella d'Arminio Monforte, Antonella Cingolani, Icona Foundation Study Group, A d'Arminio Monforte, A Antinori, S Antinori, A Castagna, R Cauda, G Di Perri, E Girardi, R Iardino, A Lazzarin, GC Marchetti, C Mussini, E Quiros‐Roldan, L Sarmati, B Suligoi, F von Schloesser, P Viale, A d'Arminio Monforte, A Antinori, A Castagna, F Ceccherini‐Silberstein, A Cingolani, A Cozzi‐Lepri, A Di Biagio, E Girardi, A Gori, S Lo Caputo, G Marchetti, F Maggiolo, C Mussini, M Puoti, CF Perno, C Torti, A Antinori, A Bandera, S Bonora, A Calcagno, D Canetti, A Castagna, F Ceccherini‐Silberstein, A Cervo, A Cingolani, P Cinque, A Cozzi‐Lepri, A d'Arminio Monforte, A Di Biagio, R Gagliardini, A Giacomelli, E Girardi, N Gianotti, A Gori, G Guaraldi, S Lanini, G Lapadula, M Lichtner, A Lai, S Lo Caputo, G Madeddu, F Maggiolo, V Malagnino, G Marchetti, A Mondi, V Mazzotta, C Mussini, S Nozza, CF Perno, S Piconi, C Pinnetti, M Puoti, E Quiros Roldan, R Rossotti, S Rusconi, MM Santoro, A Saracino, L Sarmati, V Spagnuolo, N Squillace, V Svicher, L Taramasso, C Torti, A Vergori, A Cozzi‐Lepri, S De Benedittis, I Fanti, M Giotta, C Marelli, A Rodano, A Tavelli, M Cernuschi, L Cosmaro, A Perziano, V Calvino, D Russo, M Farinella, N Policek, VL Del Negro, M Augello, S Carrara, S Graziano, G Prota, S Truffa, D Vincenti, R Rovito, M Sgarlata, Italy A Giacometti, A Costantini, V Barocci, A Saracino, C Santoro, E Milano, L Comi, C Suardi, P Viale, L Badia, S Cretella, EM Erne, A Pieri, E Quiros Roldan, E Focà, B Menzaghi, C Abeli, L Chessa, F Pes, P Maggi, L Alessio, G Nunnari, BM Celesia, J Vecchiet, K Falasca, A Pan, S Dal Zoppo, D Segala, F Bartalesi, A Bartoloni, B Borchi, C Costa, S Lo Caputo, S Ferrara, M Bassetti, E Pontali, S Blanchi, N Bobbio, C. Del Borgo, R. Marocco, G. Mancarella, S Piconi, C Molteni, S Rusconi, G Canavesi, G Pellicanò, G Marchetti, S Antinori, A Gori, M Puoti, A Castagna, A Bandera, V Bono, MV Cossu, A Giacomelli, R Lolatto, MC Moioli, L Pezzati, S Diotallevi, C Tincati, C Mussini, M Menozzi, P Bonfanti, G Lapadula, V Sangiovanni, I Gentile, V Esposito, N Coppola, FM Fusco, G Di Filippo, V Rizzo, N Sangiovanni, S Martini, AM Cattelan, D Leoni, A Cascio, M Trizzino, D Francisci, E Schiaroli, G Parruti, F Sozio, D Messeri, SI Bonelli, C Lazzaretti, R Corsini, A Antinori, R Cauda, C Mastroianni, L Sarmati, A Latini, A Cingolani, I Mastrorosa, S Lamonica, M Capozzi, M Camici, I Mezzaroma, M Rivano Capparuccia, G Iaiani, C Stingone, L Gianserra, J Paulicelli, MM Plazzi, G d'Ettore, M Fusto, M Lichtner, I Coledan, G Madeddu, A De Vito, M Fabbiani, F Montagnani, A Franco, R Fontana Del Vecchio, D Francisci, C Di Giuli, GC Orofino, G Calleri, G Di Perri, S Bonora, G Accardo, C Tascini, A Londero, G Battagin, S Nicolè, G Starnini, S Dell'Isola   +243 more
wiley   +1 more source

Improved cervical screening using HPV type restriction and cycle threshold limit setting with the AmpFire assay: A prospective screening cohort of women with and without HIV in Botswana

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective The aim of this study was to evaluate the performance of HPV type restriction and cycle threshold (Ct)‐limit setting to optimize detection of cervical intraepithelial neoplasia (CIN) with primary HPV testing. Methods Baseline cervical screening at time of entry into a prospective longitudinal cohort of women with and without HIV was ...
Rebecca Luckett, Doreen Ramogola‐Masire, Sikhulile Moyo, Annika Gompers, Anna Modest, Natasha Moraka, Thanolo Kashamba, Leabaneng Tawe, Farzad Noubary, Louise Kuhn, Surbhi Grover, Scott Dryden‐Peterson, Greta Dreyer, Joseph Makhema, Matthys H. Botha, Michele R. Hacker, Roger Shapiro   +16 more
wiley   +1 more source