Results 131 to 140 of about 3,216,105 (293)

Characteristics of patients with difficult-to-treat rheumatoid arthritis: a descriptive retrospective cohort study

open access: yesAdvances in Rheumatology
Background In 2021, an EULAR task force published a definition of difficult-to-treat rheumatoid arthritis (D2T RA). Our current knowledge of D2T RA with the EULAR definition is based on European and Asian cohorts, and no North American cohort has yet to ...
Wen Qi   +7 more
doaj   +1 more source

Janus kinase inhibitor treatment for inflammatory diseases: excess or no excess risk of venous thromboembolism?

open access: yesResearch and Practice in Thrombosis and Haemostasis
Janus kinase inhibitors (JAKis) have revolutionized the treatment landscape for various inflammatory and autoimmune diseases since their introduction in 2012. The expanded indications of JAKis have raised concerns about the associated risk of thrombosis,
Yachar Dawudi   +4 more
doaj   +1 more source

Effect of Missed Doses on the Therapeutic Effect of Methotrexate for Rheumatoid Arthritis: A Pharmacokinetic Modeling Study

open access: yesOpen Access Rheumatology: Research and Reviews, 2021
Alan Morrison,1 Melissa E Stauffer,1,2 Anna S Kaufman1 1ScribCo, Albrightsville, PA, USA; 2Scientific Editing Solutions, Walworth, WI, USACorrespondence: Alan MorrisonScribCo, 111 Gower Road, Albrightsville, PA, 18210, USATel +1 610 389-0843Email ...
Morrison A, Stauffer ME, Kaufman AS
doaj  

Randomised comparison of initial triple DMARD therapy with methotrexate monotherapy in combination with low-dose glucocorticoid bridging therapy; 1-year data of the tREACH trial [PDF]

open access: yes, 2014
Objectives To compare 1-year clinical efficacy of (1) initial triple disease-modifying antirheumatic drug therapy (iTDT) with initial methotrexate (MTX) monotherapy (iMM) and (2) different glucocorticoid (GC) bridging therapies: oral versus a single ...
Gerards, A.H. (Andreas)   +11 more
core   +3 more sources

Comparative Effectiveness and Safety of Adalimumab, Secukinumab, and Upadacitinib in Psoriatic Arthritis: A Prospective Cohort Study Based on PARWCH Cohort

open access: yesThe Journal of Dermatology, EarlyView.
ABSTRACT Psoriatic arthritis (PsA) is a chronic inflammatory disease, with prevalence among psoriasis patients ranging from 6% to 42% across populations. Although targeted therapies such as adalimumab (ADA), secukinumab (SEC), and upadacitinib (UPA) have demonstrated efficacy in randomized controlled trials, real‐world head‐to‐head comparisons remain ...
Yiyi Wang   +11 more
wiley   +1 more source

Changing trends in drug overdose mortality in Spain, 2001–2022

open access: yesAddiction, EarlyView.
Abstract Aim To measure the evolution of drug overdose mortality in Spain between 2001 and 2022. Design, Setting, Participants A repeated cross‐sectional observational study using nationwide mortality data from Spain, 2001–2022, among individuals aged 15–64 years.
Florencia Giné   +6 more
wiley   +1 more source

Magnetic resonance imaging in patients with rheumatoid arthritis with complete remission treated with disease-modifying antirheumatic drugs or anti-tumour necrosis factor agents [PDF]

open access: green, 2006
Marco Ulises Martínez‐Martínez   +5 more
openalex   +1 more source

IgG4‐Related Disease: Emerging Roles of Novel Genetic Variants, Immune Cell Subsets and Therapeutic Targets

open access: yesAllergy, EarlyView.
ABSTRACT IgG4, the least abundant IgG subclass in humans, is increasingly recognised for its involvement in allergic and autoimmune pathologies. Its unique properties, such as the tendency to form half‐molecules (one heavy chain and one light chain) and its generally non‐inflammatory nature, distinguish it from other IgG subclasses.
Louisa Tedesco   +8 more
wiley   +1 more source

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