Results 111 to 120 of about 19,083 (252)

Flare risk after oral glucocorticoid bridging with methotrexate or intra-articular bridging with triple therapy in early rheumatoid arthritis. [PDF]

open access: yesJ Intern Med
Abstract Objectives To investigate, in early rheumatoid arthritis, whether bridging with glucocorticoids (GCs) is associated with an increased risk of flare following GC tapering and withdrawal. Methods A total of 810 NOrdic Rheumatic Diseases Strategy Trials And Registries (NORD‐STAR) patients were included in this post hoc analysis: all received ...
Lend K   +16 more
europepmc   +2 more sources

Risk of urinary tract infection with SGLT2 inhibitor initiation in patients with immune‐mediated inflammatory diseases and type 2 diabetes: A target trial emulation using a Japanese hospital‐based claims database

open access: yesJournal of Diabetes Investigation, EarlyView.
In this target trial emulation of patients with immune‐mediated inflammatory diseases and type 2 diabetes, SGLT2 inhibitor initiation was not associated with a clear increase in UTI risk versus metformin, including across immunosuppressive therapy strata.
Hiroshi Tsushima   +6 more
wiley   +1 more source

Oral Microbiome in Systemic Autoimmune Diseases: A Systematic Review

open access: yesOral Diseases, EarlyView.
ABSTRACT Objective The oral cavity represents a key but underexplored interface between host immunity and microbial communities. The aim of this systematic review was to synthesize current literature on oral microbiota alterations in systemic autoimmune diseases.
Sophie Jung   +2 more
wiley   +1 more source

Avaliação das enzimas hepáticas na artrite reumatóide com a terapia de combinação metotrexato e leflunomida [PDF]

open access: yes, 2009
Trabalho de Conclusão de Curso - Universidade Federal de Santa Catarina. Curso de Medicina.
Alves, Jorge Augusto Nunes Rodrigues
core  

Novel Combination of UVA‐1 Phototherapy With Topical Tofacitinib for Treating Eosinophilic Fasciitis With Morphea: Case Report

open access: yesPediatric Dermatology, EarlyView.
ABSTRACT Eosinophilic fasciitis (EF) and morphea are rare sclerosing connective tissue disorders, and there remains debate about whether these entities are pathologically distinct or related. This case report describes the successful treatment of an adolescent patient who developed progressive morphea plaques while being treated with systemic ...
Daphne M. Cheung   +5 more
wiley   +1 more source

Antibody engineering to develop new antirheumatic therapies [PDF]

open access: yes
There has been a therapeutic revolution in rheumatology over the past 15 years, characterised by a move away from oral immunosuppressive drugs toward parenteral targeted biological therapies.
Isaacs JD
core  

The role of disease-modifying antirheumatic drugs in the implementation of the «treat-to-target» strategy for rheumatoid arthritis

open access: yesКаразінський імунологічний журнал
Background. Rheumatoid arthritis is a chronic systemic autoimmune disease that remains one of the leading causes of disability worldwide. Effective management of this condition requires a modern approach focused on the early achievement of therapeutic ...
F.V. Hladkykh
doaj   +1 more source

Medication Exposure Definitions in Perinatal Pharmacoepidemiology: Implications for Pregnancy Studies

open access: yesPaediatric and Perinatal Epidemiology, EarlyView.
ABSTRACT Background Exposure definitions in real‐world pregnancy studies vary across studies, data sources, treatments and outcomes, yet their impact on prevalence estimates remains unexamined. Objectives To identify the most used exposure definitions during the 1st trimester and evaluate their impact on prevalence estimates: Methods We reviewed 400 ...
Gabra Nohmie   +3 more
wiley   +1 more source

Comparative Risk of Alzheimer Disease and Related Dementia Among Medicare Beneficiaries With Rheumatoid Arthritis Treated With Targeted Disease-Modifying Antirheumatic Agents.

open access: yesJAMA Netw Open, 2022
Desai RJ   +9 more
europepmc   +1 more source

Periodontitis and rheumatoid arthritis—Global efforts to untangle two complex diseases

open access: yesPeriodontology 2000, EarlyView.
Abstract Understanding the impact of oral health on rheumatoid arthritis (RA) will inform how best to manage patients with both periodontitis and RA. This review seeks to provide an update on interventional and mechanistic investigations, including a brief summary of European Research programs investigating the link between periodontitis and RA. Recent
Isabel Lopez‐Oliva   +2 more
wiley   +1 more source

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