Results 91 to 100 of about 18,310 (204)

Use of healthcare administrative claims data in observational studies of antirheumatic drug effects on pregnancy outcomes: A scoping review.

PLoS ONE
The safety of antirheumatic drugs in pregnancy and their impact on maternal and neonatal outcomes are understudied. Despite pregnant individuals being excluded from clinical trials, their continued use of medications raises the importance of addressing ...
Shenthuraan Tharmarajah, Araniy Santhireswaran, Yasmeen Ameeriar, Lisa M McCarthy, Dharini Mahendira, Howard Berger, Mina Tadrous, Sara J T Guilcher   +7 more
doaj   +1 more source

Increasing the reporting of adverse drug reaction‐related hospitalizations using an ICD‐10‐based identification workflow: A multicentre study from Switzerland

British Journal of Clinical Pharmacology, Volume 92, Issue 8, Page 2937-2948, August 2026.
Background Reporting adverse drug reactions (ADRs) is essential for drug safety. In Switzerland, healthcare professionals are legally required to report serious and unlabelled ADRs, yet under‐reporting remains widespread. We tested a novel method to increase reporting of ADR‐related hospitalizations.
Georgia Anita Weber, Sophie‐Charlotte Bartel, Michael Boch, Christoph Rosen, Michael Bodmer, Balthasar Luzius Hug, Thomas Stammschulte, Patrick E. Beeler   +7 more
wiley   +1 more source

Refractory Relapsing–Remitting Adult‐Onset Still's Disease in an Adolescent Female: A Rare Case Report

Clinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT Adult‐onset Still's disease (AOSD) is a rare systemic autoinflammatory condition that presents with symptoms such as episodic fevers, a transient rash, inflammatory arthritis, and significant systemic inflammation. Diseases that have a relapsing–remitting clinical course can be challenging to diagnose and treat. We present a case of an 18 year
Tasnim Nafian, Mohd. Mujtaba Akib Bhuiyan, Kazi Ali Aftab, Khaled Mahbub Murshed, Md. Abul Kalam Azad   +4 more
wiley   +1 more source

PD‐1hiCXCR5−CD4+T Peripheral Helper Cells Were Enriched and Potentially Predicted Clinical Response to Etanercept Therapy in Rheumatoid Arthritis

MedComm, Volume 7, Issue 8, August 2026.
This study investigated the role of PD‐1hiCXCR5−CD4+ T peripheral helper (Tph) cells in rheumatoid arthritis (RA). Tph cells were increased in the peripheral blood of RA patients and associated with disease activity. Baseline Tph cell levels were linked to the response to etanercept therapy.
Haojie Xu, Wanki Ho, Lulu Cao, Dongdong Fu, Yun Li, Feng Sun, Xi Xu, Zhanguo Li, Ru Li, Hua Ye, Huaqun Zhu   +10 more
wiley   +1 more source

Chemical Profiling and In Vitro Assessment of Antioxidant and Antimicrobial Properties of Algerian Erica arborea L. Extracts, Strengthened by Molecular Modeling Analysis

ChemistryOpen, Volume 15, Issue 8, August 2026.
Erica arborea L. from Algeria was valorized via chemical profiling and bioactivity assessment. The EtOAc extract showed the highest levels of polyphenols, flavonoids, and flavonols. It exhibited strong antioxidant (ABTS•+, DPPH•, FRAP) and antibacterial activity (S. aureus, B. subtilis).
Amina Bramki, Ouided Benslama, Fatima Zohra Makhlouf, Anna Andolfi, Zineb Mokhbi, Selsabile Nedjaoum, Chawki Bensouici, Maria Michela Salvatore, Marco Masi   +8 more
wiley   +1 more source

Leveraging Administrative Health Data to Capture Rare Adverse Drug Reactions: Identifying Pediatric Patients With Trimethoprim‐Sulfamethoxazole Acute Respiratory Distress Syndrome

Pharmacology Research &Perspectives, Volume 14, Issue 4, August 2026.
ABSTRACT Rare adverse drug reactions (ADRs) are underrecognized and underreported in the electronic medical record (EMR). These events often require clinical review, making systematic identification challenging. The study aim was to develop an approach to prioritize identification and validation of a rare ADR to trimethoprim‐sulfamethoxazole causing ...
Keith Feldman, Jenna O. Miller, Katherine Doane, Laura Loftis, James W. Antoon, Kevin J. Downes, Jennifer L. Goldman   +6 more
wiley   +1 more source

Consenso 2012 da Sociedade Brasileira de Reumatologia para o tratamento da artrite reumatoide

Revista Brasileira de Reumatologia
OBJETIVO: Elaborar recomendações para o tratamento da artrite reumatoide no Brasil. MÉTODO: Revisão da literatura com seleção de artigos baseados em evidência e opinião de especialistas da Comissão de Artrite Reumatoide da Sociedade Brasileira de ...
Licia Maria Henrique da Mota, Boris Afonso Cruz, Claiton Viegas Brenol, Ivanio Alves Pereira, Lucila Stange Rezende-Fronza, Manoel Barros Bertolo, Max Victor Carioca de Freitas, Nilzio Antonio da Silva, Paulo Louzada-Júnior, Rina Dalva Neubarth Giorgi, Rodrigo Aires Corrêa Lima, Geraldo da Rocha Castelar Pinheiro   +11 more
doaj  

Mandatory Biological/Targeted Synthetic Disease-Modifying Antirheumatic Drugs Dose Reduction on Risk of Serious Infections in Patients with Rheumatoid Arthritis: A Nationwide Nested Case–Control Study

Biomedicines
Background: We aimed to investigate the risk for a serious infection in rheumatoid arthritis (RA) patients after tapering the dose of biological/targeted synthetic disease-modifying antirheumatic drugs (b/tsDMARDs).
Der-Yuan Chen, Ching-Heng Lin, Hsin-Hua Chen, Yi-Ming Chen, Kuo-Tung Tang   +4 more
doaj   +1 more source

Illness Experiences of Young Women With Rheumatoid Arthritis in South Korea

Health Expectations, Volume 29, Issue 4, August 2026.
ABSTRACT Background Rheumatoid arthritis affects young women during critical life‐course stages, requiring ongoing adaptation to illness‐related uncertainty while managing social roles and expectations. Women in their 20s to 40s face distinctive challenges related to illness disclosure, stigma and life‐course tasks, particularly around childbirth and ...
Wonhee Baek, Hyunjung Doo
wiley   +1 more source

Risk of urinary tract infection with SGLT2 inhibitor initiation in patients with immune‐mediated inflammatory diseases and type 2 diabetes: A target trial emulation using a Japanese hospital‐based claims database

Journal of Diabetes Investigation, Volume 17, Issue 8, Page 1310-1321, August 2026.
In this target trial emulation of patients with immune‐mediated inflammatory diseases and type 2 diabetes, SGLT2 inhibitor initiation was not associated with a clear increase in UTI risk versus metformin, including across immunosuppressive therapy strata.
Hiroshi Tsushima, Nobuyuki Yajima, Takashi Nomiyama, Ryoko Sakai, Hisashi Noma, Akira Katagiri, Naoto Tamura   +6 more
wiley   +1 more source