Results 71 to 80 of about 3,293,378 (262)

Bioactive Phytochemical Compounds in Medicago sativa L. (Alfalfa): A Systematic Review of Biological Properties and Therapeutic Relevance in Nutraceutical and Functional Food Implications

Food Frontiers, EarlyView.
ABSTRACT Medicago sativa L. (alfalfa) harbors a remarkably diverse reservoir of bioactive secondary metabolites. Flavonoids, isoflavones, and triterpenoid saponins dominate its bioactivity landscape, driving potent antioxidant, anti‐inflammatory, antimicrobial, estrogenic, hypolipidemic, and cytotoxic actions through redox modulation, membrane ...
Parham Joolaei Ahranjani, Hamid Rashidi Nodeh, Zahra Esfandiari, Giovanna Ferrentino   +3 more
wiley   +1 more source

Trends in Rheumatoid Arthritis Mortality Among Postmenopausal Women in the United States, 1999–2023

iMetaMed, EarlyView.
RA‐related mortality among U.S. postmenopausal women has markedly declined since 1999. Despite this overall progress, significant inequalities by race, region, and age highlight ongoing challenges in achieving equitable health outcomes. ABSTRACT Rheumatoid arthritis (RA) disproportionately affects postmenopausal women, who are at an increased risk of ...
Yuhui Zhao, Weilu Cui, Yayun Han, Jun Qiao, Minjing Chang   +4 more
wiley   +1 more source

Pharmacological considerations in pharmacotherapy of rheumatology patients with liver disease: a brief narrative review

Rheumatology
The presence of chronic liver diseases such as metabolic dysfunction-associated steatosis liver disease, viral hepatitis, and cirrhosis may affect the treatment plan in patients with rheumatologic disorders, with concern about the adverse effects of the ...
Saeedeh Shenavandeh, Seyed Alireza Taghavi, AliAkbar Nekooeian, Maryam Moini   +3 more
doaj   +1 more source

Mortality after broad‐ versus narrow‐spectrum antibiotic treatment for patients with nursing and healthcare‐associated pneumonia: A nationwide retrospective cohort study

Journal of Hospital Medicine, EarlyView.
Abstract Background Nursing and healthcare‐associated pneumonia (NHCAP) is defined as pneumonia occurring in individuals with frequent healthcare contact, such as residents of care facilities or patients with impaired activities of daily living. The effectiveness of broad‐spectrum antibiotics in treating NHCAP remains unclear.
Jumpei Taniguchi, Shotaro Aso, Hiroki Matsui, Kiyohide Fushimi, Hideo Yasunaga   +4 more
wiley   +1 more source

Cytomegalovirus retinitis during upadacitinib monotherapy for rheumatoid arthritis: a case report

Journal of Rheumatic Diseases
Janus kinase inhibitors (JAKis) are associated with increased risk of Varicella-Zoster Virus reactivation, particularly in Asian populations. While reactivation of cytomegalovirus (CMV) is very rare in rheumatoid arthritis (RA) patients on JAKis, CMV ...
Sang Jun Park, Yun Jong Lee
doaj   +1 more source

Considerations and Tips for Promoting Skin Barrier Maintenance and Quality of Life in Patients With Diabetes Mellitus: An Expert Consensus

JEADV Clinical Practice, EarlyView.
ABSTRACT Skin changes such as xerosis and pruritus are common complications among diabetes patients and may lead to serious adverse events such as diabetic foot syndrome and amputations. Evidence suggests that daily application of optimal skincare, including gentle cleansers and moisturizers, may help improve skin barrier function, preventing ...
Robert S. Kirsner, Anneke Andriessen, Brian Berman, Natasha Mesinkovska, Heather Woolery‐Lloyd, Lawrence Schachner   +5 more
wiley   +1 more source

Time‐dependent wound management protocol prevents periprosthetic joint infection in total knee arthroplasty with persistent drainage

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose This study aimed to evaluate the success rate of a standardised protocol for managing persistent wound drainage following total knee arthroplasty (TKA). Methods A prospective observational study was conducted at four institutions between January and June 2022 across primary and revision TKAs.
Filippo Leggieri, Francesco Ferriani, Enrico Di Benedetto, Enrick Miani, Enrico Festa, Giovanni Balato, Stefano M. P. Rossi, Francesco Benazzo, Andrea Baldini   +8 more
wiley   +1 more source

Registro brasileiro de biológicos: processo de implementação e resultados preliminares do BiobadaBrasil Brazilian biologic registry: BiobadaBrasil implementation process and preliminary results

Revista Brasileira de Reumatologia, 2011
OBJETIVOS: O presente estudo teve por objetivo descrever o processo de implementação de um registro nacional em um país em desenvolvimento (Brasil) e relatar os principais resultados preliminares do registro BiobadaBrasil.
David C Titton, Ines Guimarães Silveira, Paulo Louzada-Junior, Andre L Hayata, Hellen Mary S Carvalho, Roberto Ranza, Lucila S Rezende, Geraldo Castelar Pinheiro, Jair Licio F Santos, Jose Roberto Miranda, Jozelio Freitas Carvalho, Manoel Barros Bertolo, Marlene Freire, Morton A Scheinberg, Thelma L Skare, Vander Fernandes, Washington Bianchi, Ieda Maria M Laurindo   +17 more
doaj   +1 more source

Mannose Oligosaccharide‐Conjugated In Situ Pore‐Forming Injectable Hydrogels for Rheumatoid Arthritis Treatment by Reprogramming Macrophage Extracellular Vesicles

Small Methods, EarlyView.
Design of an injectable porous hydrogel modulating macrophages and their secreted EVs for joint defect repair in the pathology of rheumatoid arthritis. a) The solution containing HA and CS‐MOS, upon mixing with a crosslinker solution, undergoes porous hydrogel formation with the escape of generated CO₂ gas.
Anan Zhang, Yifan Ma, Yutong Liu, Shiyan Dong, Michelle Najarro Torres, Betty Y.S. Kim, Changsheng Liu, Lili Sun, Yuan Yuan, Wen Jiang   +9 more
wiley   +1 more source

Adherence to Subcutaneous Anti-Tumour Necrosis Factor Treatment in a Cohort of Patients with Rheumatoid Arthritis Before and After the Implementation of a Comprehensive Care Model

Biologics: Targets & Therapy, 2022
Pedro Santos-Moreno,1 Guillermo Sánchez-Vanegas,2 Angélica Monterrosa-Blanco,3 Gabriel-Santiago Rodríguez-Vargas,1 Manuel Rivero,1 Pedro Rodriguez,1 Omar-Javier Calixto,4 Adriana Rojas-Villarraga,5 Carlos Alberto Castro3 1Rheumatology Department, Biomab ...
Santos-Moreno P, Sánchez-Vanegas G, Monterrosa-Blanco A, Rodríguez-Vargas GS, Rivero M, Rodriguez P, Calixto OJ, Rojas-Villarraga A, Castro CA   +8 more
doaj