Results 101 to 110 of about 353,788 (280)

Characterizing antiseizure medication in patients with diagnosis of epilepsy in San Jose Infantil and San Jose Centro Hospitals: A retrospective cohort study in Colombia, 2019-2022

Acta Neurológica Colombiana
Introduction: Epilepsy is one of the most common neurological diseases in the world that affects millions of people. We aimed to characterize antiseizure medications (ASM) and to evaluate their clinical behavior in terms of treatment adherence and ...
Jean Paul Vergara, Karen Lorena Horta Garavito, Gregory Corena Demarchi, Valentina Galvis Palomino   +3 more
doaj   +1 more source

Barriers and enablers to antiseizure medication adherence in children with Epilepsy:A systematic review using meta-ethnography

Adherence to antiseizure medications (ASMs) is essential for seizure control in children with epilepsy. However, multiple factors influence adherence, leading to varied treatment outcomes.
Stewart, Andy, Wright, David, Smith, Caroline, Kyeremaa, Eric Amankona Abrefa, Alorabi, Majed, Lawthom, Charlotte, Scott, Sion   +6 more
core   +1 more source

Seizure detection devices in outpatient epilepsy care: High demand, low use, and the need for specialized counseling

Epileptic Disorders, EarlyView.
Abstract Objective To determine real‐world uptake of seizure detection devices (SDDs), quantify patient demand, and identify factors associated with their adoption in routine outpatient epilepsy care. Methods A monocentric cross‐sectional questionnaire‐based study was performed in outpatients at a tertiary epilepsy center.
Anthony Borho, Arthur Jordan, Tim Schrage, Miklas Mahlke, Susanna Moskau‐Hartmann, Rainer Surges, Marcel Bausch, Randi von Wrede   +7 more
wiley   +1 more source

Timing of congruent and discordant interictal epileptiform EEG discharges in focal epilepsy

Epileptic Disorders, EarlyView.
Abstract Objective Interictal epileptiform discharges (IEDs) can provide additional information for localizing the epileptogenic zone (EZ). However, due to the brevity of routine electroencephalography, IEDs are often not recorded and there is a lack of general recommendation regarding the recording duration Methods In our study, we analyzed the mean ...
Katharina Ernst, Mohammad Navab Daneshmand, Nicholas Fearns, Selina Trapp, Jan Rémi   +4 more
wiley   +1 more source

Antiseizure Medications in Adult Patients With Traumatic Brain Injury: A Systematic Review and Bayesian Network Meta-Analysis

Critical Care Explorations
OBJECTIVES:. We sought to evaluate the effectiveness of any antiseizure medication on the incidence of early post-traumatic seizures among adult patients with traumatic brain injury. DATA SOURCES:.
Federico Angriman, MD, MPH, PhD, Shaurya Taran, MD, Natalia Angeloni, MD, MSc, Catherine Devion, MLS, Jong Woo Lee, MD, PhD, Neill K. J. Adhikari, MDCM, MSc   +5 more
doaj   +1 more source

Antiseizure medications in CDKL5 encephalopathy– systematic review

Seizure: European Journal of Epilepsy
Background Cyclin-dependent kinase-like 5 deficiency disorder (CDD) is a disease belonging to the group of developmental and epileptic encephalopathies (DEE), characterized by drug-resistant epilepsy, delayed psychomotor development, premature mortality, and movement disorders.
Adrianna Kalinowska-Doman, Adam Strzelczyk, Justyna Paprocka   +2 more
openaire   +3 more sources

The effectiveness of adding on or switching antiseizure medications after the first fails to control focal epilepsy: A systematic review of randomized controlled trials

Epileptic Disorders, EarlyView.
Abstract Focal epilepsy constitutes 60–70% of epilepsy, and up to half of patients do not achieve seizure freedom with their first antiseizure medication (ASM). When the first ASM fails, evidence guiding whether to switch or add‐on another ASM and which ASMs to use is limited. This review synthesized evidence from randomized controlled trials (RCTs) on
Isaac J. Egesa, Gashirai Mbizvo, Michelle Maden, Thomas Spain, Richard Emsley, Laura J. Bonnett, Anthony G. Marson, Catrin Tudur Smith   +7 more
wiley   +1 more source

Structural pharmacology of SV2A reveals an allosteric modulation mechanism in the major facilitator superfamily

Nature Communications
The synaptic vesicle glycoprotein 2A (SV2A), a member of the major facilitator superfamily (MFS), is a key target for antiseizure medications and a biomarker for synaptic density imaging.
Shabareesh Pidathala, Xiao Chen, Yaxin Dai, Long N. Nguyen, Christoph Gorgulla, Yiming Niu, Fangyu Liu, Chia-Hsueh Lee   +7 more
doaj   +1 more source

Reflex seizures and epilepsy surgery: A network approach case‐based exploration

Epileptic Disorders, EarlyView.
Abstract Context Reflex seizures (RS) are defined by their consistent provocation by specific stimuli, encompassing a broad range from elementary sensory inputs to complex cognitive tasks. While RS are often encountered in clinical practice, their surgical management remains sparsely reported and poorly systematized.
Olivier Aron, Laure Salmon, Nicolas Nguyen, Dènahin Toffa, Sami Obaid, Alexis Robin, Dang Khoa Nguyen   +6 more
wiley   +1 more source

Multicentric study of adherence to antiseizure medications among adults with epilepsy attended in neurology departments in Burkina Faso

Epilepsia Open
Objective To study the adherence of antiseizures medication in neurology in the city of Ouagadougou. Patients and Methods We conducted a multicentric cross‐sectional study on adherence to antiseizure medications among adult patients with epilepsy ...
Alfred Anselme Dabilgou, Alassane Dravé, Julie Marie Adeline Wendlamita Kyelem, Adama Kaboré, Christian Napon, Athanase Millogo, Kapouné Karfo, Jean Kaboré   +7 more
doaj   +1 more source