Results 131 to 140 of about 8,514 (288)

Sodium‐glucose cotransporter 2 inhibitors and the risk of late onset epilepsy: A real‐world cohort study

Epilepsia, EarlyView.
Abstract Objective Late onset epilepsy (LOE) is associated with substantial morbidity. Sodium‐glucose cotransporter 2 inhibitors (SGLT2i) may exert neuroprotective effects. This study evaluated the association between SGLT2i and risk of LOE among older adults with type 2 diabetes mellitus.
Bing‐Hua Lin, Hui‐Min Huang, Hui‐An Lin, Sheng‐Feng Lin   +3 more
wiley   +1 more source

Biofluid‐specific variations in circulating 5′ transfer RNA fragments during ictal and interictal states in experimental temporal lobe epilepsy

Epilepsia, EarlyView.
Abstract Objective Circulating small noncoding RNAs represent potential biomarkers of temporal lobe epilepsy (TLE). Recently, two transfer RNA fragments (tRFs), 5′tRF Glu‐CTC and Gly‐GCC, were found to be elevated in plasma samples collected in advance of a seizure in TLE patients, suggesting they may serve as potential wet biomarkers of seizure risk ...
Marie Soukupova, Elena Perez Morrissey, Annunziata Guarino, Pietro Marino, Cristiana Pareo, Nicolò Birtolo, Saad Zaheer, Rachel Stewart, Ina Woods, Felix Rosenow, Hajo Hamer, Péter Körtvélyessy, Shona Pfeiffer, David C. Henshall, Jochen H. M. Prehn, Michele Simonato   +15 more
wiley   +1 more source

Brivaracetam and topiramate serum levels during pregnancy and delivery: a case report and a review of literature

Neurological Research and Practice
Background An increasing use of newer antiseizure medication (ASM) such as SV2A ligand brivaracetam is observed. However, data on newer antiseizure medication and therapeutic drug monitoring during pregnancy is scarce. Methods Therapeutic drug monitoring
Wiebke Hahn, Leona Möller, Katja Menzler, Tobias Poeplau, Uwe Wagner, Susanne Knake   +5 more
doaj   +1 more source

A single-center retrospective analysis of autoimmune glial fibrillary acidic protein astrocytopathy with seizures in children

Frontiers in Neurology
ObjectiveWe herein described the clinical characteristics of autoimmune glial fibrillary acidic protein astrocytopathy (GFAP-A) patients with epileptic seizures in the disease course.MethodsA single-center retrospective analysis of autoimmune GFAP-A with
Hongjun Fang, Wenjing Hu, Zhi Jiang
doaj   +1 more source

Discontinuation of Antiseizure Medications in Patients With Brain Tumors

Patients with brain tumors will experience seizures during their disease course. While providers can use antiseizure medications to control these events, patients with brain tumors can experience side effects, ranging from mild to severe, from these ...
Storstein, Anette M, Mrgula, Maciej, Gerstner, Elizabeth R, Ghiaseddin, Ashley P, Hrachova, Maya, Partap, Sonia, Dixit, Karan, Wychowski, Thomas, Templer, Jessica, Melnick, Kaitlyn, Ullrich, Nicole J, Peters, Katherine B, Walbert, Tobias   +12 more
core  

Mental health of children with epilepsy in Ukraine during the war

Epilepsia, EarlyView.
Abstract Objective The ongoing conflict in Ukraine has created a severe humanitarian crisis, disproportionately affecting vulnerable populations such as children with chronic conditions. We set out to determine information about mental health in children with epilepsy in Ukraine affected by the conflict.
Volodymyr Kharytonov, J. Helen Cross, Andriy Dubenko, Samuel Wiebe, on behalf of the ILAE Emergency Task Force for Ukraine   +4 more
wiley   +1 more source

A Systematic Review of ABCB1 Polymorphisms and Antiseizure Medication Resistance: Insights from Effect Size and Study Power Analysis

The most investigated ABCB1 single-nucleotide polymorphisms (SNPs) related to antiseizure medication resistance are rs1045642 (c.3435C>T, p.Ile1145=), rs2032582 (c.2677G>T/A, p.Ala893Ser/Thr), and rs1128503 (c.1236C>T, p.Gly412=). We conducted a
Eglė Navickienė, Zaboras, Edgaras,, Arminas Jasionis, Rūta Mameniškienė, Baronas, Karolis,, Mameniškienė, Rūta,, Karolis Baronas, Daškevičiūtė, Aurelija,, Jonas Navalinskas, Navickienė, Eglė,, Edgaras Zaboras, Jasionis, Arminas,, Aurelija Daškevičiūtė, Navalinskas, Jonas,   +13 more
core   +1 more source

Use of artificial intelligence in magnetic resonance imaging across the epileptic patient's journey: A meta‐analysis of four clinical applications

Epilepsia, EarlyView.
Abstract Objective The application of artificial intelligence/machine learning (AI/ML) to magnetic resonance imaging (MRI) promises to enhance and support clinical decision‐making in epilepsy. However, there currently lacks an appropriate assessment of clinical utility and study rigor of current AI/ML‐driven models that are targeted toward supporting ...
Judy Chen, Ella Sahlas, Yigu Zhou, Natalie Chen, Jim Xie, Farhan Wadia, Lorenzo Caciagli, Aristides Hadjinicolaou, Alexander G. Weil, Roy W. Dudley, Dewi V. Schrader, Andrea Bernasconi, Neda Bernasconi, Boris C. Bernhardt   +13 more
wiley   +1 more source

Methodological challenges in pregnancy pharmacoepidemiology : the case of antiseizure medication and offspring neurodevelopment

This thesis is driven by the overarching aim of elucidating methodological challenges inherent in pharmacoepidemiology during pregnancy, with a particular focus on antiseizure medications.
Viktor Ahlqvist (18671857)
core  

Quantitative electroencephalographic measures during postmalarial epileptogenesis

Epilepsia, EarlyView.
Abstract Objective Severe malaria with neurologic involvement contributes significantly to the global burden of acquired pediatric epilepsy. We studied quantitative electroencephalographic (EEG) measures in postmalarial epileptogenesis. Methods A total of 186 patients, aged 6 months to 11 years, with confirmed central nervous system malaria were ...
Rasesh B. Joshi, Suzanna Mwanza, Hitten P. Zaveri, Joseph Kasolo, Angela Masempela, Thelma Musakanya, Tina Mwale, Violet Nambeye, Rosemary Nyriongo, Ruth A. Tembo, Christopher Cortina, Bo Zhang, Gretchen L. Birbeck, Alexander Rotenberg, Archana A. Patel   +14 more
wiley   +1 more source