Results 181 to 190 of about 8,514 (288)

Inherited metabolic epilepsies–established diseases, new approaches

Epilepsia Open, EarlyView.
Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley   +1 more source

Late Pregnancy Antiseizure Medication Exposure and Offspring Neurodevelopmental Risk: A Multi-Child Cohort Study. [PDF]

Ann Neurol
Sheehy O, Tchuente V, Eltonsy S, Hawken S, Kaul P, Walker M, Pugliese M, Dragan R, Savu A, Leal L, Morin L, Malhamé I, Pana R, Bérard A.   +13 more
europepmc   +1 more source

Lipid‐based Nano‐delivery systems as a promising strategy for the treatment of epilepsy: Current status and challenges

Epilepsia Open, EarlyView.
Abstract Objective Epilepsy is a prevalent chronic neurological disorder characterized by abnormal neuronal electrical activity. The primary treatment modality for individuals with epilepsy (PWE) is antiseizure medication (ASM). The multiple potential factors contributing to treatment resistance in epilepsy may be attributed to the inability of ASMs to
Priya Kannan Varshini, Arunachalam Divya, Kumar Sowndharya, Parthiban Jeevitha, Selvam Manoj, Ashiq Rahman, Athil Ahamed, Ravichandiran Abirahul, Paranthaman Subash, Sulekha Khute   +9 more
wiley   +1 more source

Challenges in antiseizure medication discontinuation decisions: A qualitative study of clinicians who see patients with epilepsy. [PDF]

Clin Neurol Neurosurg
Terman SW, Kalia N, Dugan M, Silva JM, van Asch C, Burke JF, Smith SN, O'Kula SS, Hill CE.   +8 more
europepmc   +1 more source

Comparative assessment of artificial intelligence chatbots' performance in responding to healthcare professionals' and caregivers' questions about Dravet syndrome

Epilepsia Open, EarlyView.
Abstract Objective Artificial intelligence chatbots have been a game changer in healthcare, providing immediate, round‐the‐clock assistance. However, their accuracy across specific medical domains remains under‐evaluated. Dravet syndrome remains one of the most challenging epileptic encephalopathies, with new data continuously emerging in the ...
Joana Jesus‐Ribeiro, Eugenia Roza, Bárbara Oliveiros, Joana Barbosa Melo, Mar Carreño   +4 more
wiley   +1 more source

DNA methylation of antiseizure medication metabolism genes and pharmacokinetic changes in adult epilepsy patients treated with the modified Atkins diet. [PDF]

Genes Nutr
Gervin K, Kverneland M, Nakken KO, Rudi K, Iversen PO, Landmark CJ, Selmer KK.   +6 more
europepmc   +1 more source

Epilepsy syndromes classification

Epilepsia Open, EarlyView.
Abstract Epilepsy syndromes are distinct electroclinical entities which have been recently defined by the International League Against Epilepsy Nosology and Definitions Task Force. Each syndrome is associated with “a characteristic cluster of clinical and EEG features, often supported by specific etiologic findings”.
Elaine C. Wirrell, Nicola Specchio, Rima Nabbout, Phillip L. Pearl, Kate Riney   +4 more
wiley   +1 more source

Association of SCN1A and SCN2A Gene Polymorphisms with Antiseizure Medication Responsiveness: A Case-Control Study from Eastern India. [PDF]

Ann Indian Acad Neurol
Sumanth K, Sinharoy U, Joardar A, Roy S, Pandit A, Gangopadhyay G.   +5 more
europepmc   +1 more source

Medication Barriers in Pediatric Patients With Epilepsy.

BACKGROUND: To identify the most common medication adherence barriers among pediatric patients with epilepsy, standardized screening was implemented in a child neurology division using the Barriers to Adherence Tool.
DiGiovine, Marissa, Prelack, Marisa, Tencer, Jaclyn, McKee, Jillian, Ramos, Mark, Abend, Nicholas S, Kaufman, Michael C, Witzman, Stephanie, Molisani, Sara E, Tefft, Sarah, McDonnell, Pamela Pojomovsky, Gonzalez, Alexander K, Melamed, Susan, Fitzgerald, Mark, Kessler, Sudha Kilaru   +14 more
core  

Intestinal microbiome alterations in pediatric epilepsy: Implications for seizures and therapeutic approaches

Epilepsia Open, EarlyView.
Abstract The intestinal microbiome plays a pivotal role in maintaining host health through its involvement in gastrointestinal, immune, and central nervous system (CNS) functions. Recent evidence underscores the bidirectional communication between the microbiota, the gut, and the brain and the impact of this axis on neurological diseases, including ...
Teresa Ravizza, Greta Volpedo, Antonella Riva, Pasquale Striano, Annamaria Vezzani   +4 more
wiley   +1 more source