Results 191 to 200 of about 353,788 (280)

Real‐world evaluation of capillary microsampling for drug monitoring of anti‐seizure medications

Epilepsia, EarlyView.
Abstract Objective Capillary microsampling offers a minimally invasive alternative to venipuncture for therapeutic drug monitoring (TDM) of anti‐seizure medications (ASMs). We evaluated the feasibility and reliability of volumetric absorptive microsampling (VAMS) and quantitative dried blood spot (qDBS) devices for ambulatory self‐collection and at ...
Chiara Cancellerini, Alice Caravelli, Martina Soldà, Erika Esposito, Luca Vignatelli, Barbara Mostacci, Jessica Fiori, Francesca Bisulli, Laura Licchetta   +8 more
wiley   +1 more source

Targeted Sequencing and Haplotype Analysis of Voltage-Gated Potassium Channel Genes Reveal a Potential Association of <i>KCNV2</i> Haplotypes with Antiseizure Medication Response in Turkish Patients with Epilepsy. [PDF]

Pharmaceuticals (Basel)
Pekkoc-Uyanik KC, Todurga-Seven ZG, Agay ER, Uzun H.   +3 more
europepmc   +1 more source

Epileptic arousals: A neglected clinical entity

Epilepsia, EarlyView.
Abstract Objective Epileptic arousals (EAs) are seizures characterized solely by arousal from sleep. EAs are unrecognized in current seizure classifications. Their subtle semiology and inconsistently detectable ictal activity in scalp electroencephalography (EEG) complicate differentiation from physiological arousals (PAs). This study characterizes EAs
Lea Fisel, Nóra Pető, Sotirios Kalousios, Nicolas Zabler, Armin Brandt, Peter C. Reinacher, Dieter Riemann, Mohammad F. Khazali, Andreas Schulze‐Bonhage   +8 more
wiley   +1 more source

Effects of antiseizure medication load on effective brain connectivity

Brain Stimulation
S.B. Jelsma, I.B. Heijink, G.J.M. Huiskamp, R. van Griethuysen, C.H. Ferrier, P. van Eijsden, S.M.A. van der Salm, M. Zijlmans, D. van Blooijs   +8 more
doaj   +1 more source

Challenges in antiseizure medication discontinuation decisions: A qualitative study of clinicians who see patients with epilepsy. [PDF]

Clin Neurol Neurosurg
Terman SW, Kalia N, Dugan M, Silva JM, van Asch C, Burke JF, Smith SN, O'Kula SS, Hill CE.   +8 more
europepmc   +1 more source

Enhancing quality of mental health service for veterans with seizures

Epilepsia, EarlyView.
Abstract Psychiatric disorders are commonly identified in people with seizures (PWS). Comorbid mood, anxiety, and trauma‐ and stressor‐related disorders are highly prevalent and not consistently recognized or treated promptly. Veterans with seizures are particularly vulnerable to neuropsychiatric comorbidities, including a higher prevalence of ...
Maria Raquel Lopez, W. Curt LaFrance Jr., Kristen Mordecai, Anna E. Blanken, Mary Jo Pugh, Krista Ocier, Hamada Altalib   +6 more
wiley   +1 more source

Antiseizure Medication Dosing Strategy During Pregnancy and Early Postpartum in Women With Epilepsy in MONEAD. [PDF]

Neurology
Pennell PB, Li D, Kerr WT, Pack AM, French J, Gerard E, Birnbaum AK, McFarlane KN, Meador KJ, MONEAD Study Group.   +9 more
europepmc   +1 more source

Correlation of polygenic risk score and clinical phenotype in patients with genetic generalized epilepsy

Epilepsia, EarlyView.
Abstract Objective The polygenic risk score (PRS) for individuals with genetic generalized epilepsy (GGE) quantifies the common risk variants in genes identified in genome‐wide association studies. We hypothesized that the phenotype of GGE patients differs based on their GGE PRS. Methods We identified participants with highest (n = 59) versus lowest (n 
Sophie von Brauchitsch, Nils Hartung, Robin A. Karge, Bobby Koeleman, Samuel F. Berkovic, Danielle M. Andrade, Francesca Bisulli, Antonio Gambardella, Renzo Guerrini, Ingrid E. Scheffer, Ingo Helbig, Wolfram S. Kunz, Holger Lerche, Hiltrud Muhle, Christian Boßelmann, Savvas S. Papacostas, Mark I. Rees, Sanjay M. Sisodiya, Pasquale Striano, Lynnette Sadleir, Yvonne Weber, Dennis Lal, Costin Leu, Philipp S. Reif, Stefan Wolking, Felix Rosenow, Karl Martin Klein, for the Epi25 Collaborative   +27 more
wiley   +1 more source

DNA methylation of antiseizure medication metabolism genes and pharmacokinetic changes in adult epilepsy patients treated with the modified Atkins diet. [PDF]

Genes Nutr
Gervin K, Kverneland M, Nakken KO, Rudi K, Iversen PO, Landmark CJ, Selmer KK.   +6 more
europepmc   +1 more source

Status epilepticus in adults: From etiology to treatment response

Epilepsia, EarlyView.
Abstract This study explored the association between etiology of status epilepticus (SE) and treatment responsiveness. Consecutive episodes of nonhypoxic SE in patients ≥14 years old were included. Etiology was classified into acute, remote, progressive, defined electroclinical syndromes, and unknown.
Simona Lattanzi, Giada Giovannini, Niccolò Orlandi, Francesco Brigo, Eugen Trinka, Stefano Meletti   +5 more
wiley   +1 more source