Barriers and facilitators of antiseizure medication adherence: a qualitative study among persons with epilepsy in Pakistan. [PDF]
Zahra BB +8 more
europepmc +1 more source
Abstract Objective Levetiracetam (LEV) is an antiseizure medication approved for focal and generalized epilepsy. Despite its efficacy, neuropsychiatric adverse effects (NP‐AEs) may lead to treatment discontinuation. Quantitative electroencephalographic (qEEG) graph‐theoretical analysis has emerged as a valuable tool for identifying neurophysiological ...
Marco Sferruzzi +10 more
wiley +1 more source
HLA-A*2402 May Be Associated With Antiseizure Medication-Induced Severe Mucocutaneous Adverse Events in Korean Population. [PDF]
Kwack DW, Kim YG, Lee J, Kim DW.
europepmc +1 more source
Statin use and risk of remote seizure after first new onset status epilepticus
Abstract Objective Preclinical evidence supports the role of statins as antiepileptogenic agents. In this study, we investigated the risk of remote unprovoked seizures (RS) according to the use of statin therapy in a cohort of first‐ever status epilepticus (SE) survivors. Methods Retrospective analysis was made of adult patients (age ≥ 14 years) with a
Niccolò Orlandi +12 more
wiley +1 more source
The antiseizure medication stiripentol inhibits mitochondrial complex I by blocking early-stage electron transfer. [PDF]
Bouchez CL +13 more
europepmc +1 more source
Gut‐microbiota‐brain Axis and post‐traumatic epilepsy
Abstract There has been growing evidence that perturbations in gut‐microbiota‐brain axis (GMBA) are involved in mechanisms of chronic sequelae of traumatic brain injury (TBI). This review discusses the connection between GMBA and post‐traumatic epilepsy (PTE), the latter being a common outcome of TBI.
Andrey Mazarati
wiley +1 more source
Comparative performance of large language models and Drugs.com versus Lexicomp for antiseizure medication drug-drug interactions: A cross-sectional study with iterative prompting analysis. [PDF]
Mohammed M +5 more
europepmc +1 more source
Inherited metabolic epilepsies–established diseases, new approaches
Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley +1 more source
Capability, opportunity and motivation for shared decision-making about valproate as an antiseizure medication treatment for epilepsy in women with pregnancy potential: A qualitative study of patient perspectives. [PDF]
Griffiths SL +8 more
europepmc +1 more source
Abstract Objective Artificial intelligence chatbots have been a game changer in healthcare, providing immediate, round‐the‐clock assistance. However, their accuracy across specific medical domains remains under‐evaluated. Dravet syndrome remains one of the most challenging epileptic encephalopathies, with new data continuously emerging in the ...
Joana Jesus‐Ribeiro +4 more
wiley +1 more source

