Results 201 to 210 of about 45,133 (250)
Some of the next articles are maybe not open access.
Cancer Treatment Reviews, 2000
This review discusses laboratory and clinical studies of antisense oligodeoxynucleotides as potential treatments for haematological malignancies and solid tumours. Mechanisms of action, pharmacokinetics, toxicities and potential clinical applications of these agents are described.
W, Pawlak +3 more
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This review discusses laboratory and clinical studies of antisense oligodeoxynucleotides as potential treatments for haematological malignancies and solid tumours. Mechanisms of action, pharmacokinetics, toxicities and potential clinical applications of these agents are described.
W, Pawlak +3 more
openaire +2 more sources
Pharmacology of Antisense Drugs
Annual Review of Pharmacology and Toxicology, 2017Recent studies have led to a greater appreciation of the diverse roles RNAs play in maintaining normal cellular function and how they contribute to disease pathology, broadening the number of potential therapeutic targets. Antisense oligonucleotides are the most direct means to target RNA in a selective manner and have become an established platform ...
C Frank, Bennett +4 more
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Antisense agents in pharmacology
Biochemical Pharmacology, 1990This commentary is designed to evaluate the applications and potential applications of antisense agents for the pharmacologist. The issues of mechanism of the biologic response mediated by antisense oligodeoxyribonucleotides (ODNs*) and evaluation of an antisense response are discussed.
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Critical Reviews in Biochemistry and Molecular Biology, 1990
K M, Takayama, M, Inouye
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K M, Takayama, M, Inouye
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Antisense technology: an overview and prospectus
Nature Reviews Drug Discovery, 2021Xuehai Liang +2 more
exaly
Molecular Cell Biology Research Communications, 2000
M, Sohail, E M, Southern
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M, Sohail, E M, Southern
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2003
Antisense DNA technology is a method to inhibit or downregulate the production of a target protein by using antisense DNA or RNA molecules. An antisense sequence is a DNA or RNA that is perfectly complementary to the target nucleotide sequence present in the cell. There are two possible mechanisms for an antisense effect.
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Antisense DNA technology is a method to inhibit or downregulate the production of a target protein by using antisense DNA or RNA molecules. An antisense sequence is a DNA or RNA that is perfectly complementary to the target nucleotide sequence present in the cell. There are two possible mechanisms for an antisense effect.
openaire +2 more sources