Results 321 to 330 of about 443,792 (339)

Antisense Rescue

1997
Abstract Genetic manipulation of cells has provided a powerful approach to study gene function and the regulation of gene expression. Although genetic manipulation includes overexpression and ‘undcrexpression’ strategies, methods which inhibit gene function arc particularly important because they probe the usual function of a gene ...
openaire   +1 more source

Nusinersen, an antisense oligonucleotide drug for spinal muscular atrophy

Nature Neuroscience, 2017
D. Corey
semanticscholar   +1 more source

Chimeric Antisense RNAs

Antisense Research and Development, 1991
J G, Izant, A M, Hoff, A D, Sardelli, M, Ford   +3 more
openaire   +2 more sources

Antisense oligonucleotides.

Verhandelingen - Koninklijke Academie voor Geneeskunde van Belgie, 1997
Among the approaches which have been followed to convert a natural antisense phosphodiester oligonucleotide into a potential therapeutic agent, conjugation chemistry seems to be one of the most attractive. Indeed, natural phosphodiester oligonucleotide have the ideal properties (sequence specific hybridization, RNaseH activation, low or no toxicity ...
openaire   +1 more source

RNA targeting therapeutics: molecular mechanisms of antisense oligonucleotides as a therapeutic platform.

Annual Review of Pharmacology and Toxicology, 2010
C. Bennett, E. Swayze
semanticscholar   +1 more source

Antisense “Pseudogenetics”

Cell Motility, 1989
openaire   +2 more sources

Antisense Therapeutics

Biotechnology and Genetic Engineering Reviews, 1995
openaire   +2 more sources

Useful Antisense

Science, 1996
openaire   +2 more sources

Antisense RNA ☆

2013
openaire   +1 more source

Antisense oligonucleotide therapeutics

Expert Opinion on Investigational Drugs, 1999
openaire   +2 more sources