Results 271 to 280 of about 1,703,096 (348)

Research Progress on Polymer-Based Nanocarriers for Tumor-Targeted Delivery of Survivin siRNA. [PDF]

Polymers (Basel)
Ren L, Wang S, Li BC, Ding GB.
europepmc   +1 more source

Nanomedicine-driven microRNA therapy: a precision approach for eosinophilic granulomatosis with polyangiitis. [PDF]

Ann Med Surg (Lond)
Imran G, Kumari A, Khalid M, Talha M, Waafira A.   +4 more
europepmc   +1 more source

Emerging tools in plant genome editing. [PDF]

Front Genome Ed
Sharma S, Saroha NK, Sehrawat A, Tang G, Singh D, Teotia S.   +5 more
europepmc   +1 more source

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Targeted Delivery of Antisense Oligonucleotides Using Neurotensin Peptide.

Journal of Medicinal Chemistry, 2020
Despite recent advances, targeted delivery of therapeutic oligonucleotide to extra-hepatic tissues continues to be a challenging endeavor and efficient ligand-receptor systems need to be identified.
Mehran Nikan, M. Tanowitz, C. Dwyer, M. Jackson, H. Gaus, E. Swayze, F. Rigo, P. Seth, T. P. Prakash   +8 more
semanticscholar   +3 more sources

A Novel Peptide-Equipped Exosomes Platform for Delivery of Antisense Oligonucleotides.

ACS Applied Materials and Interfaces, 2021
Exosomes are natural delivery vehicles because of their original feature such as low immunogenicity, excellent biocompatibility, and migration capability.
Huiying Xu, Chong Liao, Shifu Liang, B. Ye   +3 more
semanticscholar   +1 more source

Spherical Nucleic Acids for Near-Infrared Light-Responsive Self-Delivery of Small-Interfering RNA and Antisense Oligonucleotide.

ACS Nano, 2021
Herein, we developed a photolabile spherical nucleic acid (PSNA) for carrier-free and near-infrared (NIR) photocontrolled self-delivery of small-interfering RNA (siRNA) and antisense oligonucleotide (ASO).
Lei Chen, Gaigai Li, Xingxing Wang, Jinbo Li, Yan Zhang   +4 more
semanticscholar   +1 more source

Glucagon Like Peptide 1 Receptor Agonists for Targeted Delivery of Antisense Oligonucleotides to Pancreatic Beta Cell.

Journal of the American Chemical Society, 2021
The extra hepatic delivery of antisense oligonucleotides (ASOs) remains a challenge and hampers the widespread application of this powerful class of therapeutic agents.
L. Knerr, T. P. Prakash, Richard G. Lee, William J. Drury III, Mehran Nikan, W. Fu, Elaine Pirie, Leonardo De Maria, E. Valeur, A. Hayen, M. Ölwegård-Halvarsson, J. Broddefalk, Carina Ämmälä, Michael E. Østergaard, J. Meuller, Linda Sundström, P. Andersson, D. Janzén, R. Jansson-Löfmark, P. Seth, S. Andersson   +20 more
semanticscholar   +1 more source

Delivery systems for antisense oligonucleotides

Pharmacology & Therapeutics, 2000
In vitro, the efficacy of the antisense approach is strongly increased by systems delivering oligodeoxyribonucleotides (ODNs) to cells. Up to now, most of the developed vectors favor ODN entrance by a mechanism based on endocytosis. Such is the case for particulate systems, including liposomes (cationic or non-cationic), cationic polyelectrolytes, and ...
C, Garcia-Chaumont, O, Seksek, J, Grzybowska, E, Borowski, J, Bolard   +4 more
openaire   +2 more sources