Results 301 to 310 of about 275,477 (365)

mRNA Degradation as a Therapeutic Solution for Mucopolysaccharidosis Type IIIC: Use of Antisense Oligonucleotides to Promote Downregulation of Heparan Sulfate Synthesis. [PDF]

Int J Mol Sci
Santos JI, Gonçalves M, Almeida MB, Rocha H, Duarte AJ, Matos L, Moreira LV, Encarnação M, Gaspar P, Prata MJ, Coutinho MF, Alves S.   +11 more
europepmc   +1 more source

Antisense Oligonucleotides for Rapid Translation of Gene Therapy in Glioblastoma. [PDF]

Cancers (Basel)
Desgraves JF, Mendez Valdez MJ, Chandar J, Gurses ME, Henderson L, Castro JR, Seetheram D, Ivan ME, Komotar RJ, Shah AH.   +9 more
europepmc   +1 more source

Sequence-Specific Free Energy Changes in DNA/RNA Induced by a Single LNA-T Modification in Antisense Oligonucleotides. [PDF]

Int J Mol Sci
Tomita-Sudo E, Akita T, Sakimoto N, Tahara-Takamine S, Kawakami J.   +4 more
europepmc   +1 more source

mRNA-specific readthrough of nonsense codons by antisense oligonucleotides (R-ASOs). [PDF]

Nucleic Acids Res
Susorov D, Echeverria D, Khvorova A, Korostelev AA.   +3 more
europepmc   +1 more source

Antisense oligonucleotides provide optimism to the therapeutic landscape for tauopathies. [PDF]

Neural Regen Res
Harris GA, Hirschfeld LR.
europepmc   +1 more source

Therapeutic potential of APP antisense oligonucleotides for Alzheimer's disease and down syndrome-related Alzheimer's disease. [PDF]

Mol Neurodegener
Thirumalai S, Patani R, Hung C.
europepmc   +1 more source

Characterizing the plasma protein binding profiles of chemistry diversified antisense oligonucleotides in human and mouse plasma using an ultrafiltration method. [PDF]

Front Pharmacol
Yun C, Fukami K, Shinkyo R, Jiang RR.
europepmc   +1 more source

<i>In vivo</i> efficacy and safety of systemically administered serinol nucleic acid-modified antisense oligonucleotides in mouse kidney. [PDF]

Mol Ther Nucleic Acids
Tsuboi T, Hattori K, Ishimoto T, Imai K, Doke T, Hagita J, Ariyoshi J, Furuhashi K, Kato N, Ito Y, Kamiya Y, Asanuma H, Maruyama S.   +12 more
europepmc   +1 more source

Exploring non-coding variants and evaluation of antisense oligonucleotides for splicing redirection in Usher syndrome. [PDF]

Mol Ther Nucleic Acids
García-Bohórquez B, Barberán-Martínez P, Aller E, Jaijo T, Mínguez P, Rodilla C, Fernández-Caballero L, Blanco-Kelly F, Ayuso C, Sanchis-Juan A, Broekman S, de Vrieze E, van Wijk E, García-García G, Millán JM.   +14 more
europepmc   +1 more source

Phase 1/2 trial of brogidirsen: Dual-targeting antisense oligonucleotides for exon 44 skipping in Duchenne muscular dystrophy. [PDF]

Cell Rep Med
Komaki H, Takeshita E, Kunitake K, Ishizuka T, Shimizu-Motohashi Y, Ishiyama A, Sasaki M, Yonee C, Maruyama S, Hida E, Aoki Y.   +10 more
europepmc   +1 more source