Results 111 to 120 of about 1,527,893 (148)
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Current Rheumatology Reports, 2011
Autoantibodies to eight of the aminoacyl-transfer RNA synthetases-the most well-recognized of which is anti-histidyl (Jo-1)-have all been implicated in the pathogenesis of antisynthetase syndrome (AS). AS is characterized by varying degrees of interstitial lung disease, myositis, arthropathy, fever, Raynaud's phenomenon, and mechanic's hands, and the ...
Elena, Katzap +2 more
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Autoantibodies to eight of the aminoacyl-transfer RNA synthetases-the most well-recognized of which is anti-histidyl (Jo-1)-have all been implicated in the pathogenesis of antisynthetase syndrome (AS). AS is characterized by varying degrees of interstitial lung disease, myositis, arthropathy, fever, Raynaud's phenomenon, and mechanic's hands, and the ...
Elena, Katzap +2 more
openaire +2 more sources
Joint Bone Spine, 2003
Seven autoantibodies directed against synthetases have been identified to date, the best known being anti-Jo1. Synthetases play a vital role in protein synthesis by catalyzing the acetylation of transfer RNAs (tRNAs). The most common form of antisynthetase syndrome is characterized by anti-Jo1 production, interstitial lung disease (ILD), inflammatory ...
Agathe, Imbert-Masseau +4 more
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Seven autoantibodies directed against synthetases have been identified to date, the best known being anti-Jo1. Synthetases play a vital role in protein synthesis by catalyzing the acetylation of transfer RNAs (tRNAs). The most common form of antisynthetase syndrome is characterized by anti-Jo1 production, interstitial lung disease (ILD), inflammatory ...
Agathe, Imbert-Masseau +4 more
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Calcinosis and antisynthetase syndrome
Joint Bone Spine, 2012Joint Bone Spine - In Press.Proof corrected by the author Available online since mercredi 25 juillet ...
Thierry, Zenone +2 more
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Clinical Manifestations and Treatment of Antisynthetase Syndrome
Best Practice and Research in Clinical Rheumatology, 2020Antisynthetase syndrome (ASyS) is an autoimmune disease clinically manifested most often by interstitial lung disease, myositis, and arthritis. Raynaud's syndrome, fever, and rashes are also commonly seen. This syndrome is characterized by the highly specific presence of antibodies against various aminoacyl transfer RNA synthetases, including Jo-1 and ...
Bridget F Collins
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Arthritis und Rheuma, 2022
ZUSAMMENFASSUNGDie Antisynthetase-Syndrome bilden eine Untergruppe der idiopathischen inflammatorischen Myopathien. Sie zeichnen sich aus durch mindestens eines der 3 Hauptsymptome Myositis, interstitielle Lungenerkrankung (ILD) und Arthritis in Kombination mit dem serologischen Nachweis eines Antikörpers gegen Aminoacyl-tRNA-Synthetasen.
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ZUSAMMENFASSUNGDie Antisynthetase-Syndrome bilden eine Untergruppe der idiopathischen inflammatorischen Myopathien. Sie zeichnen sich aus durch mindestens eines der 3 Hauptsymptome Myositis, interstitielle Lungenerkrankung (ILD) und Arthritis in Kombination mit dem serologischen Nachweis eines Antikörpers gegen Aminoacyl-tRNA-Synthetasen.
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Antisynthetase Syndrome Treated With Tocilizumab
Joint Bone Spine, 2016Joint Bone Spine - Sous presse. Epreuves corrigees par l'auteur.
Fabienne Coury
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Anti-Ro52 antibodies, antisynthetase antibodies, and antisynthetase syndrome
Clinical Rheumatology, 2007We present a case of antisynthetase syndrome manifesting with interstitial lung disease, mechanic's hands, nailfold abnormalities, and subclinical myositis, in the presence of antibodies to the aminoacyl tRNA synthetase PL-12 and also to Ro52. Antibodies to Ro52 have been recently associated with idiopathic inflammatory myositis, but there have only ...
Limaye, V. +4 more
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Pulmonary involvement in antisynthetase syndrome
Current Opinion in Rheumatology, 2019Purpose of review Lung involvement is a distinctive feature of antisynthetase syndrome (ASS) and it is considered a basic disease-classifying criterion. In this review, we go over clinical features, radiological patterns, prognostic factors, pathogenesis and treatment of lung involvement in ASS patients ...
Gasparotto M. +5 more
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Antisynthetase syndrome: A distinct disease spectrum
Journal of Scleroderma and Related Disorders, 2020The discovery of novel autoantibodies related to idiopathic inflammatory myopathies (collectively referred to as myositis) has not only advanced our understanding of the clinical, serological, and pathological correlation in the disease spectrum but also played a role in guiding management and prognosis.
Kun Huang, Rohit Aggarwal
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Clinical Heterogeneity and Outcomes of Antisynthetase Syndrome
Current Rheumatology Reports, 2013The autoimmune connective tissue disease antisynthetase syndrome (ASS) is an inflammatory myopathy associated with myositis-specific autoantibodies, e.g. anti-tRNA-synthetase antibodies (ASA). Since 1976 eight different ASA have been rigorously identified, of which anti-hystidyl-tRNA synthetase (anti-Jo1) is the most prevalent. Other phenotype features
Baptiste, Hervier, Olivier, Benveniste
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