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An Observational Study on the Clinical Characteristics and Prognosis of Patients With Interstitial Lung Disease Secondary to Dermatomyositis and Antisynthetase Syndrome. [PDF]
Int J RheumatolLei L +6 more
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Current Rheumatology Reports, 2011
Autoantibodies to eight of the aminoacyl-transfer RNA synthetases-the most well-recognized of which is anti-histidyl (Jo-1)-have all been implicated in the pathogenesis of antisynthetase syndrome (AS). AS is characterized by varying degrees of interstitial lung disease, myositis, arthropathy, fever, Raynaud's phenomenon, and mechanic's hands, and the ...
Elena, Katzap +2 more
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Autoantibodies to eight of the aminoacyl-transfer RNA synthetases-the most well-recognized of which is anti-histidyl (Jo-1)-have all been implicated in the pathogenesis of antisynthetase syndrome (AS). AS is characterized by varying degrees of interstitial lung disease, myositis, arthropathy, fever, Raynaud's phenomenon, and mechanic's hands, and the ...
Elena, Katzap +2 more
openaire +2 more sources
Joint Bone Spine, 2003
Seven autoantibodies directed against synthetases have been identified to date, the best known being anti-Jo1. Synthetases play a vital role in protein synthesis by catalyzing the acetylation of transfer RNAs (tRNAs). The most common form of antisynthetase syndrome is characterized by anti-Jo1 production, interstitial lung disease (ILD), inflammatory ...
Agathe, Imbert-Masseau +4 more
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Seven autoantibodies directed against synthetases have been identified to date, the best known being anti-Jo1. Synthetases play a vital role in protein synthesis by catalyzing the acetylation of transfer RNAs (tRNAs). The most common form of antisynthetase syndrome is characterized by anti-Jo1 production, interstitial lung disease (ILD), inflammatory ...
Agathe, Imbert-Masseau +4 more
openaire +2 more sources
Calcinosis and antisynthetase syndrome
Joint Bone Spine, 2012Joint Bone Spine - In Press.Proof corrected by the author Available online since mercredi 25 juillet ...
Thierry, Zenone +2 more
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Clinical manifestations and treatment of antisynthetase syndrome
Best Practice and Research in Clinical Rheumatology, 2020Antisynthetase syndrome (ASyS) is an autoimmune disease clinically manifested most often by interstitial lung disease, myositis, and arthritis. Raynaud's syndrome, fever, and rashes are also commonly seen. This syndrome is characterized by the highly specific presence of antibodies against various aminoacyl transfer RNA synthetases, including Jo-1 and ...
Bridget F Collins
exaly +3 more sources
Arthritis und Rheuma, 2022
ZUSAMMENFASSUNGDie Antisynthetase-Syndrome bilden eine Untergruppe der idiopathischen inflammatorischen Myopathien. Sie zeichnen sich aus durch mindestens eines der 3 Hauptsymptome Myositis, interstitielle Lungenerkrankung (ILD) und Arthritis in Kombination mit dem serologischen Nachweis eines Antikörpers gegen Aminoacyl-tRNA-Synthetasen.
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ZUSAMMENFASSUNGDie Antisynthetase-Syndrome bilden eine Untergruppe der idiopathischen inflammatorischen Myopathien. Sie zeichnen sich aus durch mindestens eines der 3 Hauptsymptome Myositis, interstitielle Lungenerkrankung (ILD) und Arthritis in Kombination mit dem serologischen Nachweis eines Antikörpers gegen Aminoacyl-tRNA-Synthetasen.
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Anti-Ro52 antibodies, antisynthetase antibodies, and antisynthetase syndrome
Clinical Rheumatology, 2007We present a case of antisynthetase syndrome manifesting with interstitial lung disease, mechanic's hands, nailfold abnormalities, and subclinical myositis, in the presence of antibodies to the aminoacyl tRNA synthetase PL-12 and also to Ro52. Antibodies to Ro52 have been recently associated with idiopathic inflammatory myositis, but there have only ...
Limaye, V. +4 more
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Antisynthetase syndrome treated with tocilizumab
Joint Bone Spine, 2016Joint Bone Spine - Sous presse. Epreuves corrigees par l'auteur.
Amandine, Beaumel +3 more
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