Results 11 to 20 of about 14,443 (215)

Screening for inherited thrombophilias and prophylaxis of venous thromboembolism in pregnancy and puerperium [PDF]

Romanian Journal of Medical Practice, 2020
Thrombophilias are a group of coagulation disorders associated with a predisposition to thrombotic events. They could be inherited (genetic) or acquired. The most encountered inherited thrombophilias are factor V Leiden (FVL), prothrombin gene mutation (
Ana SCUTELNICU, Corina GICA, Radu BOTEZATU, Nicolae GICA, Anca Marina CIOBANU, Brindusa CIMPOCA, Gheorghe PELTECU, Anca Maria PANAITESCU   +7 more
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Antithrombin III level in children with nephrotic syndrome, its correlation to thromboembolic complications, and serum albumin level

Saudi Journal of Kidney Diseases and Transplantation, 2021
Nephrotic syndrome (NS) is one of the most common pediatric diseases with many complications. Thromboembolic complication is the most serious complication.
Sherin Khamis Hussein, Ahmed Hafez Mohammed, Rehab Ahmed Mohammed, Hadeer Abdelghafar   +3 more
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Treatment and secondary prophylaxis of venous thromboembolism with direct oral anticoagulants in patients with severe hereditary thrombophilia

Italian Journal of Medicine, 2021
Deficiency of protein C (PC), protein S (PS), antithrombin III (AT III), and homozygosity or combined heterozygosity for Factor V Leiden (FVL) and Factor II (FII) 20210A mutation represent severe hereditary thrombophilia (SHT) and are associated with a ...
Pasquale Madonna, Anna Guida, Maria Gabriella Coppola, Paolo Tirelli, Ernesto Grasso   +4 more
doaj   +1 more source

Antithrombin III: Plasma Activity and Reference Range Among Nigerian Blood Donors

Nigerian Postgraduate Medical Journal, 2015
Background: Diagnosis of antithrombin III (ATIII) deficiency as a common cause of thrombophilia is primarily based on the determination of antithrombin levels in plasma using a functional activity assay or an immunological assay, but local reference ...
Vincent Oluseye Osunkalu, Okezie Obasi Kanu, Felix Ngwuli   +2 more
doaj   +1 more source

Quantification of antithrombin isoform proportions in plasma samples of healthy subjects, sepsis patients, and in antithrombin concentrates [PDF]

, 2002
Antithrombin (AT) circulates in plasma in two isoforms, AT-alpha (90-95%) and AT-beta (5-10%). AT isoform proportions were measured in plasma samples of 17 healthy subjects and 26 posttraumatic or postoperative septic patients, as well as in 4 ...
Donges, R., Hoffmann, J. N., Inthorn, D., Jochum, M., Muhlbayer, D., Romisch, J., Stauss, H.   +6 more
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Tromboembolias múltiplas associadas a défice de anti-trombina III.

Acta Médica Portuguesa, 1991
Congenital deficiency of antithrombin III is considered as one serious primary hypercoagulable state. The authors present a case of deficiency of antithrombin III in a 28 years old young male, with aortic valve disease and several thromboembolic events ...
C Catarino, P M Silva, J Quininha, J Serra, N da Silva, E Antunes, R Ferreira, M de Oliveira, R Gracias, A Prates   +9 more
doaj   +1 more source

A successful outcome of pregnancy in a patient with congenital antithrombin deficiency [PDF]

Vojnosanitetski Pregled, 2011
Background. Presence of inherited thrombophilia is an additional risk factor for maternal thromboembolism and certain adverse pregnancy outcomes, including recurrent fetal loss, placental abruption, intrauterine growth restriction and earlyonset severe ...
Kovač Mirjana, Miković Željko, Rakičević Ljiljana, Srzentić Snežana, Mandić Vesna, Đorđević Valentina, Radojković Dragica   +6 more
doaj   +1 more source

Antithrombin III in the prevention of thrombotic complications in high risk patients undergoing liver transplantation

Трансплантология (Москва), 2019
Introduction. Recent studies have indicated an increased incidence of thrombotic vascular complications after liver transplantation. The reasons may be associated with surgical technique and “unbalanced” hemostasis in patients with diffuse liver diseases.
N. K. Kuznetsova, E. V. Klychnikova, S. V. Zhuravel, O. D. Olisov, I. I. Utkina, M. S. Novruzbekov, V. I. Reshetnyak   +6 more
doaj   +1 more source

Overcoming heparin resistance in pregnant women with antithrombin deficiency: a case report and review of the literature

Journal of Medical Case Reports, 2018
Background The risk of thromboembolic events during pregnancy in patients with antithrombin deficiency is increased. Preventing thromboembolic events during pregnancy in the case of antithrombin deficiency is still a matter of concern.
Panagiotis Tsikouras, Anna Christoforidou, Anastasia Bothou, Dorelia Deuteraiou, Xanthoula Anthoulaki, Anna Chalkidou, Stefanos Zervoudis, Georgios Galazios   +7 more
doaj   +1 more source

An antibody that prevents serpin polymerisation acts by inducing a novel allosteric behavior [PDF]

, 2016
Serpins are important regulators of proteolytic pathways with an antiprotease activity that involves a conformational transition from a metastable to a hyperstable state. Certain mutations permit the transition to occur in the absence of a protease; when
Faull, Sarah V., Haq, Imran, Heyer Chauhan, Narinder, Irving, James A., Jagger, Alistair M., Kay, Christopher W. M., Liedtke, Maximilian, Lomas, David A., MIRANDA BANOS, MARIA ELENA, Motamedi Shad, Neda, Nanda, Arjun Scott, Ordóñez, Adriana, Perez, Juan, Salvadori, Enrico, Wort, Joshua L.   +14 more
core   +1 more source