Results 11 to 20 of about 203 (142)

Overcoming heparin resistance in pregnant women with antithrombin deficiency: a case report and review of the literature

Journal of Medical Case Reports, 2018
Background The risk of thromboembolic events during pregnancy in patients with antithrombin deficiency is increased. Preventing thromboembolic events during pregnancy in the case of antithrombin deficiency is still a matter of concern.
Panagiotis Tsikouras, Anna Christoforidou, Anastasia Bothou, Dorelia Deuteraiou, Xanthoula Anthoulaki, Anna Chalkidou, Stefanos Zervoudis, Georgios Galazios   +7 more
doaj   +1 more source

Supplementation therapy with Antithrombin Drugs in the Combined Treatment of Sepsis

Общая реаниматология, 2019
Purpose — to assess the efficacy of supplementation therapy for antithrombin deficiency in the combined treatment of sepsis.Materials and methods. A prospective-retrospective study of the efficacy of supplementation therapy for antithrombin deficiency ...
I. V. Redkin, A. F. Lopatin, A. G. Yavorovskiy, V. V. Likhvantsev   +3 more
doaj   +1 more source

Correction of Antithrombin III Deficiency in Disseminated Intravascular Coagulation

Общая реаниматология, 2008
Although antithrombin (AT) III concentrate therapy is attended by an increased risk of hemorrhage, the data available in the literature suggest that the agent may have a positive effect on outcome in disseminated intravascular coagulation (DIC ...
Ye. L. Neporada, N. A. Vorobyeva, E. V. Nedashkovsky   +2 more
doaj   +1 more source

Prevalence of thrombophilia in indian patients with deep venous thrombosis – An 8-year single-center study

Indian Journal of Vascular and Endovascular Surgery, 2022
Background: Thrombophilia is a recognized risk factor for deep venous thrombosis (DVT) and its recurrence. Routine thrombophilia testing is controversial because of low yield and high cost.
Vivek Agrawal, Sanjeev Kumar Deshpande, Brijesh Biswas, Suresh Reddy Thupakula, Vembu Anand   +4 more
doaj   +1 more source

Frequency of Protein C, S and Antithrombin III Deficiency and Presence of Antibodies of Antiphospholipid Syndrome in Women with Recurrent Abortion [PDF]

Majallah-i Zanān, Māmā̓ī va Nāzā̓ī-i Īrān, 2019
Introduction: Recurrent abortion is defined as three or more spontaneous miscarriages before first trimester of pregnancy. Protein C, S, Antithrombin III deficiency is of the min factors of this disease.
Mohammad Matin, Davoud Bashash, Kambiz Hasrak, Ahmadreza Baghestani, Mohsen Hamidpour   +4 more
doaj   +1 more source

Safety and Feasibility of Magnetic Separation‐Based Blood Purification

Advanced NanoBiomed Research, EarlyView.
We present the preclinical biological safety and translational feasibility of a magnetic nanoparticle‐based extracorporeal blood purification platform for removal of disease‐causing blood factors. ISO 10993‐compliant studies and exaggerated worst‐case exposure models demonstrate efficient nanoparticle extraction (≥99.9%), favorable biocompatibility ...
Carlos A. Mora, Laurine Rijsbergen, Jan Waskowski, Gaelle Clermont, Florian Dingreville, Chandrashekara Vishwanath, Rajesh Karunanithi, Alexander Gogos, Jean‐Claude Metzger, Manuel Baumgartner, Joerg C. Schefold, Inge K. Herrmann   +11 more
wiley   +1 more source

Comparison of Protective Effects of Recombinant Antithrombin Gamma and Plasma-Derived Antithrombin on Sepsis-Induced Disseminated Intravascular Coagulation and Multiple Organ Failure

Clinical and Applied Thrombosis/Hemostasis, 2020
In Japan, the dose of the new recombinant antithrombin III concentrate (rAT-gamma) is titrated according to patient body weight (BW), while conventional plasma-derived antithrombin concentrates (AT) are administered as a fixed dose.
Hiromitsu Kuroda MD, Yoshiki Masuda MD, PhD   +1 more
doaj   +1 more source

Hemostatic system changes predictive value in patients with ischemic brain disorders [PDF]

Vojnosanitetski Pregled, 2002
The aim of this research was to determine the importance of tracking the dynamics of changes of the hemostatic system factors (aggregation of thrombocytes, D-dimer, PAI-1, antithrombin III, protein C and protein S, factor VII and factor VIII, fibrin ...
Raičević Ranko, Jovičić Aco, Mandić-Radić Slavka, Đorđević Dragana, Magdić Bratislav, Marković Ljubo, Veljančić Dragana, Dinčić Evica, Obradović Slobodan   +8 more
doaj   +1 more source

Engineering Biology Beyond Single Genes: Advances and Challenges in Multiplex Genome Editing

Animal Research and One Health, EarlyView.
Multiplex genome editing is transforming genome engineering from single‐gene perturbation to network‐level control, yet its broader application remains limited by challenges in gRNA array engineering, delivery technologies, and safety management. Emerging AI‐driven approaches are accelerating guide RNA design and CRISPR effector optimization for ...
Linli Wang, Yongbin Liu, Hongbing Han
wiley   +1 more source

Harnessing blood clot as a native scaffold for orchestrating tissue repairs and regeneration

BMEMat, EarlyView.
The blood clot, owing to its dynamic composition and unique microenvironment, holds significant yet underappreciated potential for tissue engineering. This review systematically summarizes the pathophysiology of clot formation, the key regulatory factors shaping its microenvironment, and its applications in both pre‐clinical and clinical settings ...
Gao‐peng Dang, Yu‐zhu Wang, Yi‐fei Wang, Que Bai, Jia‐xin Hao, Zhi‐ting Li, Xiao‐qing Cao, Yu Wei, Yue Feng, Ji‐hua Chen, Franklin R. Tay, Rui‐bing Wang, Jun‐ting Gu, Li‐na Niu   +13 more
wiley   +1 more source