Results 51 to 60 of about 14,443 (215)

Estrogen as a therapeutic agent: Targeting endotheliopathy and coagulopathy in trauma

Transfusion, EarlyView.
Abstract Background Traumatic injury remains a leading cause of death, often due to uncontrolled hemorrhage and trauma‐induced coagulopathy (TIC). TIC is critically triggered by the endotheliopathy of trauma, involving endothelial cell injury and glycocalyx degradation. Despite conventional advances, the stable casualty rate underscores the urgent need
Niruktha Raghavan, Mira Patel, Bryan A. Cotton, Julia Coleman, Donald Jenkins   +4 more
wiley   +1 more source

Acute post-cardiopulmonary bypass left atrial thrombosis after mitral valvuloplasty and left atrial thrombectomy [PDF]

, 2012
A patient with mitral stenosis and multiple left atrial thrombi underwent valvuloplasty and thrombectomy. While closing the sternum after completing the cardiopulmonary bypass, a new left atrial thrombus was detected by transesophageal echocardiography ...
Dong-Hyup Lee, Tae-Eun Jung, Sang-Jin Park   +2 more
core   +1 more source

The impact of rapid infusers on the hemostatic potential of cryoprecipitate products

Transfusion, EarlyView.
Abstract Background In cases of massive transfusion, intravenous access can be limited. Additionally, delivering different products through separate lines and infusion methods adds unnecessary steps. RBC, plasma, and whole blood (WB) are delivered via rapid infusers; cryoprecipitate (CRYO) is infused through separate access and is not approved with ...
Connor D. Purvis, Samantha Redden, Andrew Jacobson, Yao‐Wei Wang, Julie Campbell, Jessica Cardenas, Jan‐Michael Van Gent, Bryan A. Cotton   +7 more
wiley   +1 more source

Is there NO treatment for severe sepsis? [PDF]

, 2008
Sepsis is a systemic inflammatory response syndrome in the presence of suspected or proven infection, and it may progress to or encompass organ failure (severe sepsis) and hypotension (septic shock).
Bredan, Amin, Cauwels, Anje
core   +2 more sources

WARFARIN INDUCED MASSIVE AND BILATERAL SKIN NECROSIS OF THE BREASTS: A CASE REPORT AND REVIEW OF THE LITERATURES [PDF]

Acta Medica Iranica, 2005
Warfarin induced skin necrosis is a rare complication associated with the use of oral ‎anticoagulants. Most patients develop this complication at the initiation of therapy. The complication is ‎usually associated with an underlying thrombophilia. Here we
A. R. Taheri H. Abdali
doaj   +2 more sources

Protein C and antithrombin III deficiency in an elderly patient presenting with pulmonary embolism

Asian Journal of Internal Medicine
Pulmonary embolism is a life-threatening condition, which if not detected and treated timely may lead to death. It is usually a consequence of deep vein thrombosis, which itself may occur due to several risk factors like prolonged immobilisation ...
R. Khan, N. Mahiyuddin, R. Tasnim, M. M. Rishad, Q. T. Islam   +4 more
doaj   +1 more source

Activated Platelet–Released Heat Shock Protein 90α Triggers Autophagy‐Dependent Neutrophil Extracellular Trap Formation and Amplifies Sepsis

Advanced Science, Volume 13, Issue 25, 4 May 2026.
HSP90α is significantly upregulated in platelets from sepsis patients, with its origin from megakaryocyte‐derived trafficking. Furthermore, activated platelets secrete HSP90α into the extracellular space in both free and exosome‐associated forms. Finally, extracellular HSP90α directly engages TLR4 on neutrophils to induce autophagy, leading to NET ...
Chengbo Wang, Maodong Leng, Chenchen Sun, Jingyu Cao, Linfei Li, Yangyang Jia, Yongshuai Han, Yuchun Liu, Yaodong Zhang, Chenglong Zhang, Yingli Men, Ningyuan Liu, Yibing Cheng, Yixia Zhang, Ya Li, Zhenlong Li, Lidan Cui, Xiangzhan Zhu   +17 more
wiley   +1 more source

Cerebral venous thrombosis in adult patients with acute lymphoblastic leukemia or lymphoblastic lymphoma during induction chemotherapy with l-asparaginase: The GRAALL experience [PDF]

, 2015
International audienceCentral nervous system (CNS) thrombotic events are a well-known complication of acute lymphoblastic leukemia (ALL) induction therapy, especially with treatments including l-asparaginase (l-ASP).
Bonmati, Caroline, Bories, Pierre, Cacheux, Victoria, Chevallier, Patrice, Couturier, Marie-Anne, Daguindau, Etienne, Dombret, Hervé, Dorvaux, Véronique, Escoffre-Barbe, Martine, Frayfer, Jamile, Huguet, Françoise, Hunault-Berger, Mathilde, Ifrah, Norbert, Lhéritier, Véronique, Orvain, Corentin, Pignon, Jean-Michel, Reman, Oumedaly, Sanhes, Laurence, Suarez, Felipe, Tanguy-Schmidt, Aline, Thomas, Xavier   +20 more
core   +4 more sources

Thrombophilias, or trouble never comes alone

Cardiologia Hungarica
Venous thromboembolism is being recognized increasingly at a young age, with not only the etiological role of the COVID-19-pandemic being considered but also the rarer occurrences of thrombophilias and the regional clustering of certain diseases.
Márk Söjtöry, Nóra Klenk, Nóra Sebő, Gergely György Nagy   +3 more
doaj   +1 more source

Multiple Myeloma Presenting as Lower Gastrointestinal Bleeding: A Case Report

Clinical Case Reports, Volume 14, Issue 5, May 2026.
ABSTRACT Multiple myeloma (MM) is a malignant hematologic neoplasm that primarily affects the bone marrow and can invade other organs, leading to diverse clinical manifestations. Presentation with gastrointestinal bleeding as the initial symptom is exceptionally rare.
Ahmed Arabi, Naseem Ambra, Asgad Mohamed Ahmed Eltigani, Asma Ahmed Yousif, Abdelkarim Hashim Mohamed   +4 more
wiley   +1 more source