Results 181 to 190 of about 6,430 (232)
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Acta Endocrinologica, 1992
We studied the antithyroid action of cigarette smoking products (nicotine, cotinine, and thiocyanate) in the physiological culture system of porcine thyroid follicles. Iodide uptake, iodine organification, de novo thyroid hormone formation, and iodide efflux were measured in the presence of 0–200 μmol/l nicotine, cotinine, or potassium thiocyanate ...
H, Fukayama +3 more
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We studied the antithyroid action of cigarette smoking products (nicotine, cotinine, and thiocyanate) in the physiological culture system of porcine thyroid follicles. Iodide uptake, iodine organification, de novo thyroid hormone formation, and iodide efflux were measured in the presence of 0–200 μmol/l nicotine, cotinine, or potassium thiocyanate ...
H, Fukayama +3 more
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l-METHYL-2-MERCAPTOIMIDAZOLE: A NEW ACTIVE ANTITHYROID AGENT*
The Journal of Clinical Endocrinology & Metabolism, 1951SINCE thiouracil, the first antithyroid drug, became available, additional related compounds have received clinical trial. Chief among the group (Table 1) are thiourea, thiobarbital, aminothiouracil, propylthiouracil, methylthiouracil, iodothiouracil, Meprocil (a combination of methylthiouracil and propylthiouracil) and the newest member, 1-methyl- 2 ...
ELMER C. BARTELS, ROBERT W. SJOGREN
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[Antithyroid agents related agranulocytosis: Literature review].
La Revue de medecine interne, 2017The antithyroid agents (carbimazole, methimazole, thiamazole, propylthiouracil and benzylthiouracile) are the drug class that is associated with a high risk of agranulocytosis. Acute and profound (
E, Andrès +7 more
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Atom Level Electrotopological State Indexes in QSAR: Designing and Testing Antithyroid Agents
Pharmaceutical Research, 1996To design antithyroid agents with less side effects, the electrotopological-state (E-state) indexes of thiourylene moiety (SN&S) was utilized as a guideline to develop five acrylic thiourylene-type compounds with reduced antioxidant property.These agents were synthesized and screened for antithyroid activity in rats using 125I-thiocyanate discharge ...
R R, Abou-Shaaban +3 more
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ChemInform Abstract: POTENTIAL ANTITHYROID AGENTS. III: N‐ARYLFORMAMIDINO‐N‐ARYLTHIOCARBAMIDES
Chemischer Informationsdienst, 1981AbstractDie substituierten Formamidinothioharnstoffe (IV), die nach dem angegebenen Schema hergestellt werden, weisen antithyroide Aktivität auf.
J. S. UPADHYAYA, P. K. SRIVASTAVA
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[Antineutrophil cytoplasmic antibody associated vasculitis induced by antithyroid agents].
Zhonghua yi xue za zhi, 2003To investigate the significance of antineutrophil cytoplasmic antibody (ANCA) in hyperthyroidism at different stages and treated with different drugs and to investigate the relationship between the ANCA specific target antigens and the clinical manifestations of vasculitis.Two hundred and sixteen patients with hyperthyroidism were divided into four ...
Xiao-hui, Guo +4 more
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