Results 111 to 120 of about 47,153 (259)
A Targeted Therapeutic Rescues Botulinum Toxin-A Poisoned Neurons [PDF]
, 2008 Botulinum neurotoxin (BoNT), a Category A biothreat agent, is the most potent poison known to mankind. Currently no antidote is available to rescue poisoned synapses.
Bal Ram Singh +6 more
core +1 more source
Shaping Pulses to Control Bistable Biological Systems [PDF]
, 2015 In this paper we study how to shape temporal pulses to switch a bistable system between its stable steady states. Our motivation for pulse-based control comes from applications in synthetic biology, where it is generally difficult to implement real-time ...
Angeli, David +3 more
core +2 more sources
Veterinary Medicine and Science, Volume 11, Issue 4, July 2025.ABSTRACT Background Bisphenol A (BPA) is an endocrine‐disrupting chemical, and it is mostly used in plastic industries. Naringin is a potent flavonoid that has been reported to possess several beneficial pharmacological properties such as antioxidant, anti‐inflammatory, and antiapoptotic properties.
Leah Oluwaseyanu Esuola +11 more
wiley +1 more source
The Immunizing Effects of Antitoxin [PDF]
The Boston Medical and Surgical Journal, 1895 n ...
openaire +3 more sources
Influence of Different Transposon Families on Genomic Stability of Shewanella oneidensis MR1
Microbial Biotechnology, Volume 18, Issue 7, July 2025.This study aimed for targeted genome stabilisation in Shewanella oneidensis MR1 through two approaches: complete ISSOD2 inactivation via CRISPR‐deaminase‐mediated stop codon integration, and megaplasmid size reduction (35% deletion). Analysis revealed ISSOD2 as the most active transposon family (84% activity) and identified transposition hotspots for ...
Benjamin Fritz +2 more
wiley +1 more source
Structural insights into chaperone addiction of toxin-antitoxin systems
Nature Communications, 2019 SecB homologs can be associated with stress-responsive type II toxin–antitoxin (TA) systems and form tripartite toxin-antitoxin-chaperone systems (TAC).
Valérie Guillet +12 more
doaj +1 more source
A tetraspecific VHH-based neutralizing antibody modifies disease outcome in three animal models of Clostridium difficile infection [PDF]
, 2016 Clostridium difficile infection (CDI), a leading cause of nosocomial infection, is a serious disease in North America, Europe, and Asia. CDI varies greatly from asymptomatic carriage to life-threatening diarrhea, toxic megacolon, and toxemia.
Beamer, Gillian +12 more
core +2 more sources
B Cells as a Host of Persistent Salmonella Typhimurium
Immunology, Volume 175, Issue 3, Page 292-299, July 2025.B cells: a niche for persistent Salmonella enterica serovar Typhimurium (S. Tm). In vitro, within B cells and in the absence of antibiotics, a persistent population of S. Tm emerges, where the SehA/B gene is implicated. Additionally, a replicative population of S. Tm is also present. Upon antibiotic administration, approximately 90% of the S.
Alonso D. Cruz‐Cruz +4 more
wiley +1 more source