Results 121 to 130 of about 447,103 (266)

Antitumor efficacy of a novel CLA-PTX microemulsion against brain tumors: in vitro and in vivo findings

, 2012
Dan Li,1 Ke Yang,1 Jie-Si Li,1 Xi-Yu Ke,1 Yu Duan,1 Ruo Du,1 Ping Song,1 Ke-Fu Yu,1 Wei Ren,1 Dan Huang,1 Xing-Huo Li,1 Xin Hu,1 Xuan Zhang,1 Qiang Zhang1,21Department of Pharmaceutics, 2State Key Laboratory of Natural and Biomimetic Drugs, School of ...
Ren W, Du R, Huang D, Yu KF, Li D, Yang K, Hu X, Ke XY, Li XH, Zhang Q, Li JS, Song P, Zhang X, Duan Y   +13 more
core  

Chemical Strategies for Multistimuli Responsive Dynamic Covalent Materials in Regenerative Medicine

Advanced Healthcare Materials, EarlyView.
Multistimuli responsive dynamic covalent materials integrate reversible chemistry with the complex chemical, mechanical, and biochemical cues of regenerative environments. This review highlights chemical strategies based on orthogonal dynamic bonds, multicomponent networks, and hierarchical architectures to regulate mechanics, degradation, and ...
Saurabh Joshi, Matthew B. Baker, Dominik Schauenburg   +2 more
wiley   +1 more source

A Hybrid Bioprinting–Microfabrication Approach to Controllable Multitype Spheroid Arrays for Modeling Tumor Heterogeneity

Advanced Healthcare Materials, EarlyView.
This work introduces a “cancer‐in‐a‐well” technology that recreates tumor heterogeneity in vitro using multitype spheroid arrays. Combining bioprinting/microdispensing with microstructured culture devices, the system improves drug screening and modeling of tumor complexity.
Simone Bonetti, Eva Clemente, Emanuela Mensà, Marco de Maria, Fulvia Farabegoli, Emanuela Saracino, Barbara Bortolani, Emanuela Marcelli, Renato Brandimarti, Dario de Biase, Giampaolo Zuccheri   +10 more
wiley   +1 more source

Titanium isopropoxide complexes supported by pyrrolyl Schiff base ligands: syntheses, structures, and antitumor activity

, 2014
The syntheses, structures and antitumor activity of four titanium isopropoxide complexes supported by pyrrolyl Schiff base ligands are reported. Treatment of Ti(OPr)(4) with 2 equivalents of HL1 (HL1 = N-(1H-pyrrol- 2-ylmethylene)(2-pyridinyl)methanimine)
Lin, MS (Lin, Miaoshui), Cao, YH (曹玉华), Wu, J (Wu, Jian), Li, YH (Li, Yahong), Liu, W (Liu, Wei), Pei, H (Pei, Hao), Chen, YM (Chen, Yanmei)   +6 more
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Lignin Mimicking Protein Methylation Augments the Efficacy of FOLFOX Chemotherapy by Anchoring Thymidylate Synthase

Advanced Materials, EarlyView.
Lignin‐mimicking protein methylation can enhance the efficacy and mitigate the toxicity of the classic FOLFOX chemotherapy regimen. ABSTRACT FOLFOX has served as the standard chemotherapy regimen for advanced stages, specifically in the treatment of pancreatic, colorectal, and bladder cancers.
Shiyao Song, Yan‐Lai Tang, Xiaoting Liu, Jiayi Zheng, Chong Wu, Tang Li, Junhong Ye, Dianmin Xia, Yong Mei, Jingxuan Ma, Libin Huang, Xuequn Luo, Liheng Chen, Yanlin Qin, Weiling He   +14 more
wiley   +1 more source

Highly Stable Antitumor Silver-Lipid Nanoparticles Optimized for Targeted Therapy [PDF]

Ammar Darwish,1 Nikolett Sándor,1 Imre Szenti,2 Tamás Marosvölgyi,3 Kata Juhász,1 Andrea Rónavári,2 Edi Kachal,2 Bence Kutus,4 Zoltán Kónya,2 Zsolt Balogi1 1Institute of Biochemistry and Medical Chemistry, Medical School, University of Pécs, Pécs, H-7624,
Kachal E, Sándor N, Juhász K, Darwish A, Szenti I, Kutus B, Rónavári A, Kónya Z, Marosvölgyi T, Balogi Z   +9 more
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Phase Engineering of Atomically Precise Nanoclusters (APNCs) of Gold and Beyond

Advanced Materials, EarlyView.
Engineering the structural phase of materials is of paramount importance for both fundamental research and practical applications. In this Review, we summarize the recent progress in controlling the phases of atomically precise nanoclusters (APNCs) of gold, silver and copper, as well as bimetallic systems. The phase‐enabled material properties of APNCs
Yitong Wang, Avirup Sardar, Weijie Ji, Zhongyu Liu, Rongchao Jin   +4 more
wiley   +1 more source

Strategies and Recent Advances on Improving Efficient Antitumor of Lenvatinib Based on Nanoparticle Delivery System [PDF]

Haiqing Wang,1,* Wentao Bo,1,* Xielin Feng,1 Jinliang Zhang,1 Ge Li,2 Yan Chen3 1Department of Hepatopancreatobiliary Surgery, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital and Institute, Affiliated Cancer Hospital of ...
Li G, Zhang J, Feng X, Chen Y, Wang H, Bo W   +5 more
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Anisotropic Masked Mycobacterium Potentiates Amplified Antitumor Trained Immunity via Spleen Targeting and Myelopoiesis Conversion

Advanced Materials, EarlyView.
An engineered Trojan Mycobacterium, developed via a “peeling‐off and masking‐up” strategy, functions as a powerful splenic myelopoiesis converter. This spleen‐targeted nanomedicine induces trained immunity to reprogram immunosuppressive myeloid reservoirs into antitumoral effectors.
Jin‐Ho Choi, Sang Nam Lee, Jang Hun Heo, Soyoung Park, Sei Hyun Park, Yong Taik Lim   +5 more
wiley   +1 more source

Preparation, characterization, and evaluation of antitumor effect of Brucea javanica oil cationic nanoemulsions

, 2016
Ting-ting Liu,1–3 Li-Qiu Mu,1–3 Wei Dai,1–3 Chuan-bang Wang,1–3 Xin-Yi Liu,1–3 Da-Xiong Xiang1–3 1Department of Pharmacy, The Second Xiangya Hospital, 2Institute of Clinical Pharmacy, Central South University, 3Key ...
Xiang DX, Liu XY, Liu TT, Dai W, Wang CB, Mu LQ   +5 more
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