Results 191 to 200 of about 491,510 (368)

A novel strategy for treating oncogene‐mutated tumors by targeting tumor microenvironment and synergistically enhancing anti‐PD‐1 immunotherapy

Cancer Communications
Yingqiang Liu, Linjiang Tong, Mengge Zhang, Qi Zhang, Qiupei Liu, Fang Feng, Yan Li, Mengzhen Lai, Haotian Tang, Yi Chen, Meiyu Geng, Wenhu Duan, Jian Ding, Hua Xie   +13 more
doaj   +1 more source

The central role of radiotherapy in remodeling the tumor immune microenvironment: mechanisms and therapeutic implications. [PDF]

Front Cell Dev Biol
Yi Z, Chen N, Jiang X, Hu X.
europepmc   +1 more source

Antitumor Activity of Thiosugars

YAKUGAKU ZASSHI, 1967
Masuo Akagi, Setsuzo Tejima, Masanobu Haga, Yasuko Hirokawa, Masaatsu Yamada, Masako Ishiguro, Den-ichi Mizuno   +6 more
openaire   +3 more sources

Near‐Infrared‐Driven Metal–Organic Frameworks‐Based Nanorobots for Controlled Photothermal‐Chemical Therapy Synergistic Induction of Cancer Cell Death

Advanced Robotics Research, EarlyView.
To achieve efficient cancer cell death, a bowl‐shaped PDA@UiO‐66@DOX nanorobot drug‐delivery nanoplatform was developed. Near‐infrared irradiation not only drives the nanorobot to exhibit self‐thermophoretic motion and elevates temperature but also triggers Doxorubicin (DOX) release via hyperthermia, enhancing cancer cells uptake of DOX and thereby ...
Tong Lin, Jie Yang, Yongcheng Li, Yuepeng Cai, Xiaosong Zhou, Ting Chen, Renfeng Dong   +6 more
wiley   +1 more source

Activation of tumor-specific CD8+ T cells prior to radiopharmaceutical therapy improves antitumor response. [PDF]

J Immunother Cancer
Shim D, Mouton C, Moseman JE, Comas Rojas H, Jeon D, Idrissou MB, Hernandez R, Weichert JP, McNeel DG.   +8 more
europepmc   +1 more source

Proteomic Analysis of DNA−Protein Cross-Linking by Antitumor Nitrogen Mustards [PDF]

, 2010
Rachel Loeber, Erin D. Michaelson-Richie, Simona G. Codreanu, D.C. Liebler, Colin Campbell, Natalia Tretyakova   +5 more
openalex   +1 more source

Stromal‐Derived IL‐8 Promotes M2 Macrophage Polarization via the RhoA/MRTF‐A/SRF Transcriptional Axis to Impair CD8+ T Cell Cytotoxicity in Lung Cancer

Advanced Science, EarlyView.
In the recondite pulmonary neoplastic milieu, DESMIN+ cancer‐associated fibroblasts function as the paramount stromal source of IL‐8, precipitating a deleterious immunological metamorphosis by engaging CXCR2 receptors on the myeloid lineage. This paracrine stimulus triggers a mechanotransduction cascade characterized by RhoA‐dependent actin ...
Xuyu Gu, Qiyu Fang, Jia Yu, Ting Yu, Huashan Shi, Kaiqi Jin, Lei Jiang, Wentian Zhang   +7 more
wiley   +1 more source

Enhanced Antitumor Immunity Through T Cell Activation with Optimized Tandem Double-OX40L mRNAs [PDF]

Zhuoya Deng,1– 3,* Yuying Tian,1,* Jing Wang,1 Yongru Xu,1 Zherui Liu,3,4 Zhaohui Xiao,1 Zhaohai Wang,1 Minggen Hu,1 Rong Liu,1 Penghui Yang1 1Faculty of Hepato-Pancreato-Biliary Surgery, Institute of Hepatobiliary Surgery, the First Medical ...
Liu Z, Xiao Z, Tian Y, Deng Z, Hu M, Yang P, Liu R, Wang J, Wang Z, Xu Y   +9 more
core   +1 more source

Repurposing COVID-19 (and other) mRNA vaccines to boost cancer immunotherapy efficacy: mechanistic insights and future directions. [PDF]

J Immunother Cancer
Gujar S, Pol JG, Vijayan VV, Gopalakrishnan Nair P, Babukuttan Sheela U, Banerjee A, Kroemer G.   +6 more
europepmc   +1 more source

Targeting ALKBH5 with mefloquine as a therapeutic strategy to enhance antitumor immunity in osteosarcoma. [PDF]

Victoria Mai, Manjeet Rao
openalex   +1 more source