Results 211 to 220 of about 491,510 (368)

Tumor‐Derived LAMB3 Drives Immunosuppressive LRRC15+ Fibroblast Formation During Pancreatic Ductal Adenocarcinoma Development

Advanced Science, EarlyView.
A single‐cell atlas of pancreatic ductal adenocarcinoma development reveals progressive ductal‐fibroblast‐immune crosstalk. Tumor‐derived LAMB3 drives the formation of immunosuppressive LRRC15+ fibroblasts through the ITGB1/FAK/MAPK/FOSL2 signaling. Glycolytic reprogramming upregulates LAMB3 and correlates with LRRC15+ fibroblast enrichment.
Xuqing Shi, Hangqi Liu, Jianru Sun, Xiaoding Liu, Xinping Jv, Longyun Chen, Yuhan Zhang, Hui Zhang, Xudong Xing, Ruiyu Li, Xinyi Ke, Jun Wang, Xianglin Yin, Bohan Liu, Qixian Liu, Yuan Wang, Junliang Lu, Shiyi Liu, Junyi Pang, Yumeng Cai, Menghua Dai, Fan Bai, Huanwen Wu, Zhiyong Liang   +23 more
wiley   +1 more source

Rearming mesenchymal stem cells with engineering strategies to combat cancer. [PDF]

Front Immunol
Yu T, Jin S, Xu R, Zhang Y, Wang X.
europepmc   +1 more source

Combined antitumor effects of HpD-photoradiation and hyperthermia using a gold vapor laser

, 1988
Hajime Yamamoto, Haruo Hisazumi, Hiroshi Morishita, Kazuyoshi Nakajima, Tadao Uchibayashi, Katsusuke Naito   +5 more
openalex   +2 more sources

Studies in plant tissue culture: potential sources of clinically important antitumor agents [PDF]

, 1982
J. P. KUTNEY
openalex   +1 more source

Chemoproteomic Identification of AKT2 as a Paclitaxel‐Binding Protein via C─C Bond‐Linked Probe PTX‐4 in Paclitaxel‐Resistant Breast Cancer

Advanced Science, EarlyView.
ABSTRACT Breast cancer remains one of the most prevalent malignancies among women, and taxane‐based chemotherapies such as paclitaxel and docetaxel are central to standard treatment regimens. However, drug resistance in breast cancer limits therapeutic efficacy and contributes to recurrence and metastasis.
Kai Wang, Yuqing Yuan, Wei Shen, Xiuxiu Yang, Xiaokang Wu, Haihua Zhou, Yi Hu, Qing Zhu   +7 more
wiley   +1 more source

Glycolytic reprogramming in cancer: immune crosstalk, nutrient competition, and supportive care perspectives. [PDF]

Front Immunol
Wu H, Wang Y, Tian Y, Feng S, Yang X, Yuan X, Fan L, Feng Q, Liu Z, Zhao Q.   +9 more
europepmc   +1 more source

220. Chemotherapy in Combination with T-Cell Therapy Results in Significant Antitumor Activity and Improved Clinical Outcomes for EBV-Associated Nasopharyngeal Carcinoma [PDF]

, 2011

openalex   +1 more source

HNRNPU K181 Lactylation Drives Cervical Cancer Growth by Upregulating PHGDH and Reprogramming Serine Metabolism

Advanced Science, EarlyView.
Lactate in cervical cancer induces HNRNPU K181 lactylation, opposed by NAA50‐mediated acetylation and suppressed by Pazopanib. This lactylation enhances HNRNPU binding to PHGDH pre‐mRNA exon 1, maintaining exon 1‐containing transcripts and mRNA stability, thereby activating serine metabolism.
Chang Zhang, Qingfei Meng, Hui Jiao, Huixin Liu, Xiangchao Wang, Honglan Zhou, Yishu Wang   +6 more
wiley   +1 more source

BTLA and PD-1 combined with radiotherapy for enhancing antitumor immune response in lung cancer via the regulation of memory B cells to promote T-cell infiltration. [PDF]

Transl Lung Cancer Res
Zhang Y, Li Y, Feng C, Yang Y, Liang N, Qiao L, Xie J, Zhang Y, Hu P, Deng G, Zhang J.   +10 more
europepmc   +1 more source

Tumor-targeted hybrid micelles enable ROS-responsive CO release and synergistic chemo–gas antitumor therapy

Zhanglong Huang, Shiwei Ding, Lili Zhong, Chenxi Liu, Xiaofei Li, Dan He   +5 more
openalex   +1 more source