Results 231 to 240 of about 447,103 (266)

SPRED2 Negatively Regulates CD8⁺ T Cell-Mediated Antitumor Immunity in Breast Cancer. [PDF]

Adv Sci (Weinh)
Tian M, Yoshimura T, Zhao K, Li C, Gao T, Wang Z, Fujisawa M, Ohara T, Matsukawa A.   +8 more
europepmc   +1 more source

ICOS‐ImmunoPET Monitors T Cell Activation After Combination Immune Checkpoint Blockade in a Mouse Model of Melanoma Brain Metastasis

Advanced Science, EarlyView.
ICOS‐immunoPET noninvasively visualizes activated T cells in melanoma brain metastases following combined anti‐PD‐1/anti‐CTLA‐4 therapy. Clinical translation of this imaging approach may improve patient stratification and treatment monitoring and serve as a quantitative imaging endpoint to support immunotherapy development and clinical trials in brain ...
Renesmee C. Kuo, Rohit Verma, Sydney C. Nagy, Mausam Kalita, Samuel Aubert, Josué Ballesteros‐Álvarez, Pedro Machado Almeida, Hannes Vogel, Israt S. Alam, Michael Lim, Michelle L. James   +10 more
wiley   +1 more source

Advances in Radiotherapy for Neoadjuvant Therapy of Stage III Non-Small Cell Lung Cancer. [PDF]

Cancer Sci
Mao Q, Yu Y, Fang Y, Zhu S, Tang C, Cai J.   +5 more
europepmc   +1 more source

Gut microbiome-mediated primary and acquired resistance to immune checkpoint inhibitors in MSI-H/dMMR colorectal cancer: mechanisms, biomarkers, and therapeutic implications-a narrative review. [PDF]

Front Cell Infect Microbiol
Marjanović M, Maletin N, Kukić B, Nikolić I, Petrović N, Radić J, Đurić A, Knezević M, Dejanović B, Ćalić V.   +9 more
europepmc   +1 more source

Concerted Action of Targeted Nucleic Acid Therapeutics as Flexible, Precision and Personalized Cancer Treatment

Advanced Science, EarlyView.
Combinations of small activating RNAs and small interfering RNAs were developed as personalized precision therapies that simultaneously activate tumor suppressors and silence oncogenes according to the molecular signatures of patient tumors. This combination strategy demonstrated superior anticancer efficacy, highlighting the promise of precision ...
Jing Wu, Jiaxuan Chen, Abdechakour Elkihel, Wenjun Lan, Nicolas Fraunhoffer, Dandan Zhu, Baoping Lian, Christina Galanakou, Zhancun Bian, Xi Liu, Odile Gayet, Loic Moubri, Julie Aglietti Roques, Vikash Reebye, Nagy Habib, Xiaoxuan Liu, Nelson Dusetti, Juan Lucio Iovanna, Ling Peng   +18 more
wiley   +1 more source

Hypomethylation of GNA15 Promotes Pancreatic Ductal Adenocarcinoma Progression and Macrophage M2 Polarization via STAT3‐CXCL8 Axis

Advanced Science, EarlyView.
A schematic model summarizing GNA15's mechanism in mediating macrophage M2 polarization and Gemcitabine resistance. ABSTRACT The complexity of pancreatic ductal adenocarcinoma (PDAC) progression, coupled with the lack of effective immunotherapy, underscores the imperative to deepen our understanding of its mechanisms and identify suitable immune ...
Weihui Guo, Zhenyuan Qian, Lei Wang, Weilang Xu, Yuxin Weng, Kai Jiang, Zaiyuan Ye, Ji Xu, Guangyuan Song   +8 more
wiley   +1 more source

Porosity-engineered long-acting protopanaxadiol microspheres prevent CDK4/6 inhibitor-induced myelosuppression. [PDF]

Mater Today Bio
Zhang A, Zhu Y, Kong X, Liu Z, Tan M, Yu H, Jing G, Gou J, Yin T, He H, Zhang Y, Zhang X, Liu K, Xiao P, Tang X.   +14 more
europepmc   +1 more source

Roles of exosome-mediated macrophage polarization in the hepatocellular carcinoma progression. [PDF]

Front Immunol
Chen A, Zhu M.
europepmc   +1 more source

Context-Dependent cGAS-STING Activation Shapes Metastatic Progression and Dormancy. [PDF]

Cells
Akter-Yasuoka E, Lee T, Murayama T, Nakayama J.   +3 more
europepmc   +1 more source

Erratum: Safety, Tolerability, and Antitumor Activity of Zipalertinib Among Patients With Non-Small-Cell Lung Cancer Harboring Epidermal Growth Factor Receptor Exon 20 Insertions. [PDF]

J Clin Oncol
Piotrowska Z, Shao-Weng Tan D, Smit EF, Spira AI, Soo RA, Nguyen D, Ho-Fun Lee V, Chih-Hsin Yang J, Velcheti V, Wrangle JM, Socinski MA, Koczywas M, Janik JE, Jones J, Yu HA.   +14 more
europepmc   +1 more source