Results 171 to 180 of about 8,172 (215)
Some of the next articles are maybe not open access.
Venoms, antivenoms and immunotherapy
Toxicon, 1998A century after the discovery of antivenom and despite real progress undertaken in its manufacture, its use remains largely empirical. Recent studies of pharmacokinetics of envenoming permitted improved understanding of immunotherapy. Improved purification of the antivenom by using immunoglobulin fragments has lead to increased tolerance and efficiency
/Chippaux, Jean-Philippe, Goyffon, M.
openaire +2 more sources
Toxin-resolved antivenomics-guided assessment of the immunorecognition landscape of antivenoms
Toxicon, 2018Snakebite envenoming represents a major issue in rural areas of tropical and subtropical regions across sub-Saharan Africa, South to Southeast Asia, Latin America and Oceania. Antivenoms constitute the only scientifically validated therapy for snakebite envenomings, provided they are safe, effective, affordable, accessible and administered ...
Juan J. Calvete +3 more
openaire +2 more sources
BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy, 2013
The first advance on crude filtered immune serum or plasma for treating systemically envenomed bite victims was the use of IgG (predominantly equine) precipitated by salt treatment. This was followed by the development of F(ab')(2) antivenoms, prepared using pepsin digestion to remove both the highly reactive and nonspecific Fc part of the IgG molecule
R D, Theakston, D C, Smith
openaire +1 more source
The first advance on crude filtered immune serum or plasma for treating systemically envenomed bite victims was the use of IgG (predominantly equine) precipitated by salt treatment. This was followed by the development of F(ab')(2) antivenoms, prepared using pepsin digestion to remove both the highly reactive and nonspecific Fc part of the IgG molecule
R D, Theakston, D C, Smith
openaire +1 more source
Antivenom, anecdotes and evidence
Medical Journal of Australia, 2004Envenoming is rare in Australia - multicentre studies are needed to improve the tenuous evidence base.
openaire +2 more sources
Antivenom research in Australia
Medical Journal of Australia, 1994Australia has the most potent collection of venomous land and sea creatures in the world--something that settlers to this country discovered by bitter experience. Fortunately, today victims of bites from such animals may benefit from more effective and rational treatment than is available in most other countries.
openaire +2 more sources
Antivenomics of a European vipera antivenom
Toxicon, 2016Davinia Pla +3 more
openaire +1 more source
Science's STKE, 2002
Higashino et al. found that in mammals (specifically mice), as in venomous snakes, there is a circulating inhibitor of secreted phospholipase A 2 (PLA 2 ). Secreted PLA 2 can activate cellular signaling pathways through interaction with the PLA
openaire +1 more source
Higashino et al. found that in mammals (specifically mice), as in venomous snakes, there is a circulating inhibitor of secreted phospholipase A 2 (PLA 2 ). Secreted PLA 2 can activate cellular signaling pathways through interaction with the PLA
openaire +1 more source
Recent advancements in snake antivenom production
International Journal of Biological Macromolecules, 2023Anurag S Rathore
exaly