Results 211 to 220 of about 10,138,177 (397)

Divergent Delivery and Expression Kinetics of Lipid and Polymeric Nanoparticles across mRNA Modalities

open access: yesAdvanced Science, EarlyView.
Self‐amplifying (saRNA), linear (linRNA), and circular (circRNA) mRNAs are compared under standardized conditions using lipid nanoparticles (LNPs) and pABOL polymer. saRNA achieved superior expression, while linRNA and circRNA performance varied based on untranslated region elements and delivery method.
Irafasha C. Casmil   +12 more
wiley   +1 more source

Studies on Antiviral Agents. V. Synthesis and Antiviral Activity of N-Chloro Compounds.

open access: bronze, 1967
Hidetaka Yuki   +5 more
openalex   +2 more sources

Biomolecular Interaction Prediction: The Era of AI

open access: yesAdvanced Science, EarlyView.
This review offers a thorough examination of recent progress in deep learning for predicting biomolecular interactions, including those involving proteins, nucleic acids, and small molecules. It covers data processing strategies, representative model architectures, and evaluation metrics, while highlighting current methodological limitations.
Haoping Wang, Xiangjie Meng, Yang Zhang
wiley   +1 more source

Dual‐Ligand Strategy in Rh‐Catalyzed Sequential Hydrofunctionalization of Valylene

open access: yesAdvanced Science, EarlyView.
A remarkable dual‐ligand strategy is employed in Rh‐catalyzed sequential coupling reaction of dinucleophiles and 1,3‐enynes with high regio‐ and chemo‐selectivity. Abstract Controlling regio‐ and chemo‐selectivity in transition‐metal‐catalyzed reactions involving coupling reagents with multiple reactive sites remains a significant challenge.
Yong‐Kang Mei   +4 more
wiley   +1 more source

Antiviral Activity of Intranasally Applied Human Leukocyte Interferon [PDF]

open access: green, 1978
Stephen B. Greenberg   +3 more
openalex   +1 more source

Mechanistic Insights in Surface Engineering of Micro‐/Nanocomposite Phase Change Materials for Thermal Energy Storage: A Review

open access: yesAdvanced Energy and Sustainability Research, EarlyView.
This review examines surface‐engineered phase change material composites as vital solutions for escalating thermal energy storage demands driven by urbanization. It elucidates their enhanced performance through chemical mechanisms, diverse compositions, and preparation strategies, emphasizing the role of carbon‐based additives in improving thermal ...
Laxman Singh   +11 more
wiley   +1 more source

FIB‐3 index as a novel age‐independent predictor of liver fibrosis and prognosis in hepatocellular carcinoma patients undergoing hepatectomy

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
Fibrosis‐3 index (FIB‐3) can stratify the risk of the survival and the recurrence‐free survival. The FIB‐3 index is a reliable, age‐independent tool for assessing liver fibrosis and prognosis in HCC patients post‐hepatectomy. Its use may improve clinical outcomes and support personalized treatment strategies. Abstract Background Liver fibrosis is a key
Yuki Imaoka   +13 more
wiley   +1 more source

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