Results 241 to 250 of about 10,450,245 (405)

Arzanol Inhibits Human Dihydroorotate Dehydrogenase and Shows Antiviral Activity. [PDF]

J Nat Prod
Alberti M, Tamburello M, Salamone S, Gallinella G, Sanna C, Appendino GB, Lolli ML, Massarotti A, Pollastro F, Miggiano R.   +9 more
europepmc   +1 more source

Human DICER helicase domain recruits PKR and modulates its antiviral activity

, 2021
Thomas Montavon, Morgane Baldaccini, Mathieu Lefèvre, Erika Girardi, Béatrice Chane-Woon-Ming, Mélanie Messmer, Philippe Hammann, Johana Chicher, Sébastien Pfeffer   +8 more
openalex   +2 more sources

Membralin Assembles a MAN1B1–VCP Complex to Target Foreign Glycoproteins from the Endoplasmic Reticulum to Lysosomes for Degradation

Advanced Science, EarlyView.
This study identifies Membralin as an ER‐phagy receptor that recruits MAN1B1 and VCP to form a selective ERLAD complex. By sensing dense N‐glycan clusters on viral fusion glycoproteins, this ubiquitin‐independent pathway directs SARS‐CoV‐2 spike, Ebola GP, influenza HA, and HIV‐1 Env to lysosomal degradation, thereby limiting viral infectivity ...
Jing Zhang, Xiaoran Lu, Sunan Li, Tao Wang, Iqbal Ahmad, Yong‐Hui Zheng   +5 more
wiley   +1 more source

Antiviral Activity of Eugenol Against Chinese Rice-Field Eel Rhabdovirus in <i>Monopterus albus</i>. [PDF]

Animals (Basel)
Jiang J, Xue M, Liu W, Zhou Y, Li Y, Fan Y.   +5 more
europepmc   +1 more source

TRIM25 Is Required for the Antiviral Activity of Zinc Finger Antiviral Protein

Journal of Virology, 2017
Xiaojiao Zheng, Xinlu Wang, Fan Tu, Qin Wang, Z. Fan, G. Gao   +5 more
semanticscholar   +1 more source

Identification of Mannose‐Capped‐Arabinomannan 101‐mer as a Potential Influenza Virus Vaccine Adjuvant

Advanced Science, EarlyView.
Well‐defined and synthetic mannose‐capped arabinomannan 101‐mer from Mycobacterium tuberculosis cell wall was identified as a potent influenza vaccine adjuvant, boosting the antibody response, realizing full protection and showing excellent safety. ABSTRACT Many natural bacterial components as adjuvants can activate the host immune system, but the ...
Yu‐Fang Zhang, Ruihong Xu, Jia Luo, Yuxin Ma, Guozhi Xiao, Ye Liu   +5 more
wiley   +1 more source

Discovery of a Marine <i>Beauveria bassiana</i> Polysaccharide with Antiviral Activity Against Tobacco Mosaic Virus. [PDF]

Mar Drugs
Qiu X, Jiao L, Xue J, Xu G, Tang X.
europepmc   +1 more source

“Self” and “Nonself” Manipulation of Interferon Defense during Persistent Infection: Bovine Viral Diarrhea Virus Resists Alpha/Beta Interferon without Blocking Antiviral Activity against Unrelated Viruses Replicating in Its Host Cells

, 2006
Matthias Schweizer, Philippe Mätzener, Gabriela Pfaffen, Hanspeter Stalder, Ernst Peterhans   +4 more
openalex   +1 more source

Amelioration of Post‐Stroke Edema and Microcirculatory Dysfunction via Targeted AQP4 Inhibition While Preserving the Glymphatic System

Advanced Science, EarlyView.
Compared to untargeted therapy, the targeted nanocarrier, Angiopep‐2‐conjugated Lipid Nanoparticle (A‐LNP) loaded with TGN‐020 (TGN), selectively accumulated in stroke‐injured regions. It suppressed local aquaporin‐4 (AQP4) overexpression, thereby alleviating cerebral edema and hypoperfusion while preserving global glymphatic clearance.
Lei Jin, Zeyu Yang, Boyang Wei, Yu Wu, Longxiang Li, Jiaming Zhou, Xin Zhang, Fa Jin, Shixing Su, Yanchao Liu, Ran Li, Shenquan Guo, Xingwu Liu, Yu Cai, Hong Liu, Min Chen, Wenchao Liu, Chuanzhi Duan, Xifeng Li   +18 more
wiley   +1 more source

A Flavonoid-Rich Extract of Scoparia dulcis L. Exhibits Antiviral Activity against Herpes Virus Type 1. [PDF]

Chem Biodivers
Jales FLML, Siqueira EMDS, Dantas-Medeiros R, de Araújo ERD, Alves JSF, Rocha HAO, Lopes NP, Ferreira LS, Tavares EA, Zucolotto SM.   +9 more
europepmc   +1 more source