Results 261 to 270 of about 438,323 (304)

Antiviral activity of benzimidazole derivatives. II. Antiviral activity of 2-phenylbenzimidazole derivatives

Bioorganic & Medicinal Chemistry, 2010
Seventy-six 2-phenylbenzimidazole derivatives were synthesized and evaluated in cell-based assays for cytotoxicity and antiviral activity against a panel of 10 RNA and DNA viruses. The most commonly affected viruses were, in decreasing order, CVB-2, BVDV, Sb-1, HSV-1, and YFV, while HIV-1 and VSV were not affected, and RSV, VV and Reo-1 were only ...
TONELLI, MICHELE, SIMONE M, TASSO, BRUNO, NOVELLI, FEDERICA, BOIDO, VITO, SPARATORE, FABIO, PAGLIETTI G, PRICL S, GILBERTI G, BLOIS S, IBBA C, SANNA G, LODDO R, LA COLLA P.   +13 more
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ANTIVIRAL ACTIVITY OF MEROCYANINE 540

Photochemistry and Photobiology, 1987
Abstract Simultaneous exposure to the lipophilic dye merocyanine 540 (MC 540) and white light inactivates several enveloped viruses. The same treatment appears to have little or no effect on pluripotent hematopoietic stem cells, mature red cells, and mature leukocytes. At least some components of the clotting system are spared, too. The molecular basis
F, Sieber, J M, O'Brien, G J, Krueger, S L, Schober, W H, Burns, S J, Sharkis, L L, Sensenbrenner   +6 more
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Antiviral activity of glycyrrhizic acid

Experientia, 1980
Glycyrrhizic acid inhibits the growth of several DNA and RNA viruses in cell cultures and inactivates Herpes simplex 1 virus irreversibly.
R, Pompei, A, Pani, O, Flore, M A, Marcialis, B, Loddo   +4 more
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Antiviral Activities of Photoactive Perylenequinones

Photochemistry and Photobiology, 1997
AbstractNine perylenequinones (PQ), including some familiar naturally occurring pigments, were compared for their light‐mediated antiviral efficacies. Calphostin C was the most active compound against the two target viruses, herpes simplex virus type 1 and Sindbis virus. Hypo‐crellins A and B were also very active.
J B, Hudson, V, Imperial, R P, Haugland, Z, Diwu   +3 more
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Antiviral activity of Inonotus hispidus

Fitoterapia, 2003
The antiviral activity of two phenolic compounds, hispolon and hispidin, isolated from the fruit bodies of the basidiomycete Inonotus hispidus as well as of some extracts prepared from fruit bodies and mycelial cultures of this fungus was investigated in allantois on the shell-test system.
N A, Awadh Ali, R A A, Mothana, A, Lesnau, H, Pilgrim, U, Lindequist   +4 more
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Nucleoside analogs with antiviral activity

Biochemical Pharmacology, 1976
Effects of chemical agents on viruses are discussed with regard to inhibition of virus adsorption, inhibition of virus penetration and uncoating, and inhibition of an intracellular event. The following nucleosides are discussed with regard to desirable features, toxicity, solubility, and mutagenic and carcinogenic properties: 5-iodo-2'-deoxycytidine, 5-
W H, Prusoff, D C, Ward
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Antiviral Activity of Tenuazonic Acid

Nature, 1963
TENUAZONIC acid (I) was first isolated by Rosett et al.1 from culture filtrates of various strains of Alternaria tenuis. The recent report2 of antitumour activity of tenuazonic acid prompts us to report our results with this mould metabolite. During an antiviral screening programme culture filtrates of an Aspergillus were found to inhibit the ...
F A, MILLER, W A, RIGHTSEL, B J, SLOAN, J, EHRLICH, J C, FRENCH, Q R, BARTZ, G J, DIXON   +6 more
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The antiviral activity of dideoxycytidine

Journal of Antimicrobial Chemotherapy, 1989
2',3'-Dideoxycytidine (ddc) is a 2',3'-dideoxypyrimidine nucleotide which has been shown to be active against human immunodeficiency virus type 1 (HIV-1) in cell cultures. This article reviews some of the laboratory studies with this antiviral compound, and available pharmacokinetic and toxicity data from phase 1 studies of ddc alone and in alternation
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The Antiviral Activities of Tetherin

2013
Tetherin (BST2/CD317) has emerged as a key host cell defense molecule, inhibiting the release and spread of diverse enveloped virions from infected cells. In this chapter, I review the molecular and cellular basis for tetherin's antiviral activities and the function of virally encoded countermeasures that disrupt its function. I further describe recent
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The antiviral activity of Isoprinosine

Canadian Journal of Microbiology, 1972
A hypothesis predicting that increase in the rate of synthesis of host messenger RNA would be associated with antiviral activity was examined. Biochemically, Isoprinosine or NPT-10381 (methisoprinol) increased the rate of rapid labeling of polyribosomal RNA and protein in uninfected monkey kidney cells in tissue culture.
P, Gordon, E R, Brown
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