Results 271 to 280 of about 293,855 (303)

The antiviral activity of dideoxycytidine

Journal of Antimicrobial Chemotherapy, 1989
2',3'-Dideoxycytidine (ddc) is a 2',3'-dideoxypyrimidine nucleotide which has been shown to be active against human immunodeficiency virus type 1 (HIV-1) in cell cultures. This article reviews some of the laboratory studies with this antiviral compound, and available pharmacokinetic and toxicity data from phase 1 studies of ddc alone and in alternation
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Nucleoside analogs with antiviral activity

Biochemical Pharmacology, 1976
Effects of chemical agents on viruses are discussed with regard to inhibition of virus adsorption, inhibition of virus penetration and uncoating, and inhibition of an intracellular event. The following nucleosides are discussed with regard to desirable features, toxicity, solubility, and mutagenic and carcinogenic properties: 5-iodo-2'-deoxycytidine, 5-
W H, Prusoff, D C, Ward
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The Antiviral Activities of Tetherin

2013
Tetherin (BST2/CD317) has emerged as a key host cell defense molecule, inhibiting the release and spread of diverse enveloped virions from infected cells. In this chapter, I review the molecular and cellular basis for tetherin's antiviral activities and the function of virally encoded countermeasures that disrupt its function. I further describe recent
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Naphthyridines with Antiviral Activity - A Review

Medicinal Chemistry, 2017
Naphthyridine scaffold is an important pharmacophore in compounds which have shown various biological activities like antiviral, antimicrobial, anticancer, antiinflammatory and analgesic. This scaffold is also reported to exhibit activity against HIV, HCMV, HSV, HPV and HCV.
Inder P, Singh, Sanjay, Kumar, Shiv, Gupta   +2 more
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A Review of the Antiviral Activity of Berberine

Current Drug Discovery Technologies
Berberine is an isoquinoline alkaloid with strong pharmacological activity such as analgesic, antioxidant, neuroprotective, antivirus, anti-inflammatory, anti-seizure, anti-obesity, and hypolipidemic effects. Accumulated evidence indicates berberine plays an inhibitory role against infection of numerous viruses, including human immunodeficiency virus,
Fatemeh, Forouzanfar, Zahra, Meshkat
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The Antiviral Activity of Chitosan (Review)

Applied Biochemistry and Microbiology, 2002
Data on the inhibitory effect of chitosan on viral infections in animals, plants, and microorganisms are reviewed. The effects of the physicochemical parameters and structure of chitosan on its antiviral activity are analyzed. Possible mechanisms of the inhibitory effect of chitosan on viral infections are discussed.
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Antiviral Activity of Glyoxals

Nature, 1957
C A, DE BOCK, J, BRUG, J N, WALOP
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Antiviral Activity of Gliotoxin

Chemotherapia, 2009
N M, Larin, M P, Copping, R H, Herbst-Laier, B, Roberts, R B, Wenham   +4 more
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Metabolism and antiviral activity of ribavirin

Virus Research, 2005
Thirty years after its synthesis, the mechanism of action of ribavirin is still not completely understood. Although much is known about the metabolism and biochemical effects of ribavirin in human cells, there is still much to be learned about the precise mechanism of action of ribavirin with the various viruses.
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ANTIVIRAL ACTIVITY OF SELECTED BENZIMIDAZOLES.

Bollettino dell'Istituto sieroterapico milanese, 1963
Sarà inserito alla riapertura delle ...
Fara GM, Cochrane KW
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