Results 261 to 270 of about 10,107,736 (396)

Approaches to repurposing reverse transcriptase antivirals in cancer

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
This review highlights the role of reverse transcriptase (RT) inhibition in cellular regulation associated with non‐terminal repeat retrotransposons and endogenous retroviruses. Based on their pleiotropic characteristics, RT inhibitors (RTIs) are discussed as potential anticancer agents.
Richard Head   +2 more
wiley   +1 more source

Nuclear shuttling of CDC4 mediated broad-spectrum antiviral activity against diverse coronaviruses. [PDF]

open access: yesEmerg Microbes Infect
Li M   +14 more
europepmc   +1 more source

Antiviral Activity of Extracts from Marine Algae

open access: green, 1978
James T. Richards   +5 more
openalex   +1 more source

Prescription drug use in breastfeeding mothers and infant exposure: A register‐based cohort study

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Breast milk is the optimal infant nutrition; however, many infants may be exposed to prescription drugs if used by their mothers during breastfeeding. The aim of this study was to evaluate the prevalence and patterns of prescription drug use among breastfeeding mothers and to assess the availability of relative infant dose information for
Ditte Resendal Gotfredsen   +5 more
wiley   +1 more source

Iron improves the antiviral activity of NK cells. [PDF]

open access: yesFront Immunol
Schimmer S   +11 more
europepmc   +1 more source

TRIM25 Is Required for the Antiviral Activity of Zinc Finger Antiviral Protein

open access: yesJournal of Virology, 2017
Xiaojiao Zheng   +5 more
semanticscholar   +1 more source

Physics of Protein Aggregation in Normal and Accelerated Brain Aging

open access: yesBioEssays, EarlyView.
Soluble monomeric proteins precipitate via nucleation into insoluble amyloids in response to age‐related exposures (e.g., microbes, nanoparticles). Persistent soluble‐to‐insoluble phase transition depletes the functional proteins. In normal aging, replacement matches loss; in accelerated aging, it does not.
Alberto J. Espay   +9 more
wiley   +1 more source

Antiviral activity of silver nanoparticles against H1N1 influenza virus. [PDF]

open access: yesBMC Res Notes
Seyfi M   +5 more
europepmc   +1 more source

Transcriptomic functional characterization of recombinant adeno‐associated virus producing cell line adapted to suspension‐growth

open access: yesBiotechnology Progress, EarlyView.
Abstract Recombinant adeno‐associated virus (rAAV) is a widely used delivery vehicle in gene therapy. A scalable production technology is essential for its wide clinical applications. We have taken a synthetic biology approach to generate HEK293‐based cell lines which harbor integrated genetic elements encoding essential AAV and adenoviral helper ...
Han‐Jung Kuo   +6 more
wiley   +1 more source

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