Results 291 to 300 of about 355,010 (330)

Antiviral activities of lactoferrin

Antiviral Research, 2001
Lactoferrin (LF) is an iron binding glycoprotein that is present in several mucosal secretions. Many biological functions have been ascribed to LF. One of the functions of LF is the transport of metals, but LF is also an important component of the non-specific immune system, since LF has antimicrobial properties against bacteria, fungi and several ...
Grietje Molema, Leonie Beljaars, Dirk K. F. Meijer, Martin C. Harmsen, B. W. A. van der Strate   +4 more
openaire   +3 more sources

Antiviral activities of hypericin

Antiviral Research, 1991
Hypericin, a photodynamic plant quinone, readily inactivated murine cytomegalovirus (MCMV), Sindbis virus, and human immunodeficiency virus type 1 (HIV-1), especially on exposure to fluorescent light. Sindbis virus was significantly more sensitive than MCMV.
G. H. N. Towers, James B. Hudson, I. Lopez-Bazzocchi   +2 more
openaire   +3 more sources

Antiviral activity of indole derivatives

Antiviral Research, 2009
Unsymmetrical methylene derivatives 5 were prepared following a known method, by reaction of the Mannich bases of 2-naphthols 4 with indoles. All synthesized compounds were tested against a wide panel of viruses, since previous work showed that Mannich bases on 7-hydroxycoumarin 1 and unsymmetrical methylene derivatives 2 were endowed with some ...
GIAMPIERI M, BALBI A, MAZZEI M, LA COLLA P, IBBA, CRISTINA, LODDO, ROBERTA   +5 more
openaire   +5 more sources

The antiviral activity of dideoxycytidine

Journal of Antimicrobial Chemotherapy, 1989
2',3'-Dideoxycytidine (ddc) is a 2',3'-dideoxypyrimidine nucleotide which has been shown to be active against human immunodeficiency virus type 1 (HIV-1) in cell cultures. This article reviews some of the laboratory studies with this antiviral compound, and available pharmacokinetic and toxicity data from phase 1 studies of ddc alone and in alternation
openaire   +3 more sources

The Antiviral Activities of Tetherin

2013
Tetherin (BST2/CD317) has emerged as a key host cell defense molecule, inhibiting the release and spread of diverse enveloped virions from infected cells. In this chapter, I review the molecular and cellular basis for tetherin's antiviral activities and the function of virally encoded countermeasures that disrupt its function. I further describe recent
openaire   +4 more sources

Antiviral activity of benzimidazole derivatives. II. Antiviral activity of 2-phenylbenzimidazole derivatives

Bioorganic & Medicinal Chemistry, 2010
Seventy-six 2-phenylbenzimidazole derivatives were synthesized and evaluated in cell-based assays for cytotoxicity and antiviral activity against a panel of 10 RNA and DNA viruses. The most commonly affected viruses were, in decreasing order, CVB-2, BVDV, Sb-1, HSV-1, and YFV, while HIV-1 and VSV were not affected, and RSV, VV and Reo-1 were only ...
TONELLI, MICHELE, SIMONE M, TASSO, BRUNO, NOVELLI, FEDERICA, BOIDO, VITO, SPARATORE, FABIO, PAGLIETTI G, PRICL S, GILBERTI G, BLOIS S, IBBA C, SANNA G, LODDO R, LA COLLA P.   +13 more
openaire   +4 more sources

Antiviral activity of glycyrrhizic acid

Experientia, 1980
Glycyrrhizic acid inhibits the growth of several DNA and RNA viruses in cell cultures and inactivates Herpes simplex 1 virus irreversibly.
Alessandra Pani, Maria Antonietta Marcialis, B. Loddo, O. Flore, Raffaello Pompei   +4 more
openaire   +3 more sources

ANTIVIRAL ACTIVITY OF MEROCYANINE 540

Photochemistry and Photobiology, 1987
Abstract Simultaneous exposure to the lipophilic dye merocyanine 540 (MC 540) and white light inactivates several enveloped viruses. The same treatment appears to have little or no effect on pluripotent hematopoietic stem cells, mature red cells, and mature leukocytes. At least some components of the clotting system are spared, too. The molecular basis
Sheri L. Schober, Gregory J. Krueger, Jill M. O'Brien, Lyle L. Sensenbrenner, William H. Burns, Fritz Sieber, Saul J. Sharkis   +6 more
openaire   +3 more sources

Antiviral Activities of Photoactive Perylenequinones

Photochemistry and Photobiology, 1997
AbstractNine perylenequinones (PQ), including some familiar naturally occurring pigments, were compared for their light‐mediated antiviral efficacies. Calphostin C was the most active compound against the two target viruses, herpes simplex virus type 1 and Sindbis virus. Hypo‐crellins A and B were also very active.
James B. Hudson, Richard P. Haugland, Zhenjun Diwu, V. Imperial   +3 more
openaire   +3 more sources

Antiviral Activity of Tenuazonic Acid

Nature, 1963
TENUAZONIC acid (I) was first isolated by Rosett et al.1 from culture filtrates of various strains of Alternaria tenuis. The recent report2 of antitumour activity of tenuazonic acid prompts us to report our results with this mould metabolite. During an antiviral screening programme culture filtrates of an Aspergillus were found to inhibit the ...
Wilton A. Rightsel, John Ehrlich, F. A. Miller, Glen J. Dixon, James C. French, Bernard J. Sloan, Quentin R. Bartz   +6 more
openaire   +3 more sources