Results 61 to 70 of about 10,107,380 (301)

Assessment of in-vitro cytotoxicity and in-ovo virucidal antiviral efficacy of various plant extracts and bioactive molecules [PDF]

Kafkas Universitesi Veteriner Fakültesi Dergisi
The viral diseases that occurred in recent years have increased the interest in non-toxic to healthy cells and naturally isolated agents to struggle with these diseases.
Furkan Ozan ÇÖVEN, Seray GÜR, Ece UYAR, Karrar Ali Mohammed Hasan ALSAKINI, Fatih KARABEY, Fethiye ÇÖVEN, İhsan ÇALIŞ, Ayşe NALBANTSOY   +7 more
doaj   +1 more source

Evaluation of Essential Oils and Extracts of Rose Geranium and Rose Petals as Natural Preservatives in Terms of Toxicity, Antimicrobial, and Antiviral Activity

Pathogens, 2021
Essential oils (EOs) and extracts of rose geranium (Pelargonium graveolens) and petals of rose (Rosa damascena) have been fully characterized in terms of composition, safety, antimicrobial, and antiviral properties. They were analyzed against Escherichia
Chrysa Androutsopoulou, Spyridoula D. Christopoulou, Panagiotis Hahalis, Chrysoula Kotsalou, Fotini N. Lamari, Apostolos Vantarakis   +5 more
doaj   +1 more source

Identification of a 3-Alkylpyridinium Compound from the Red Sea Sponge Amphimedon chloros with In Vitro Inhibitory Activity against the West Nile Virus NS3 Protease. [PDF]

, 2018
Viruses are underrepresented as targets in pharmacological screening efforts, given the difficulties of devising suitable cell-based and biochemical assays.
Duggan, Brendan M, Emwas, Abdul-Hamid, Gerwick, William H, Kharbatia, Najeh, Kremb, Stephan, O'Rourke, Aubrie, Raji, Misjudeen, Sioud, Salim, Voolstra, Christian R   +8 more
core   +3 more sources

Antiviral Activities of Silymarin and Derivatives [PDF]

Molecules, 2019
Silymarin flavonolignans are well-known agents that typically possess antioxidative, anti-inflammatory, and hepatoprotective functions. Recent studies have also documented the antiviral activities of silymarin and its derivatives against several viruses, including the flaviviruses (hepatitis C virus and dengue virus), togaviruses (Chikungunya virus and
Hsin Ya Hsu, Alagie Jassey, Liang Tzung Lin, Ching Hsuan Liu   +3 more
openaire   +4 more sources

Lethal Mutagenesis of Poliovirus Mediated by a Mutagenic Pyrimidine Analogue [PDF]

, 2007
Lethal mutagenesis is the mechanism of action of ribavirin against poliovirus (PV) and numerous other RNA viruses. However, there is still considerable debate regarding the mechanism of action of ribavirin against a variety of RNA viruses.
Brown, Daniel M., Cameron, Craig E., Edathil, Jocelyn P., Franco, David, Graci, Jason D., Harki, Daniel A., Korneeva, Victoria S., Loakes, David, Paul, Aniko V., Peterson, Blake R., Smidansky, Eric D., Too, Kathleen   +11 more
core   +4 more sources

Antiviral Drug Research Proposal Activity

Journal of Microbiology & Biology Education, 2011
The development of antiviral drugs provides an excellent example of how basic and clinical research must be used together in order to achieve the final goal of treating disease.
Lisa Injaian, Ann C. Smith, Jennifer German Shipley, Gili Marbach-Ad, Brenda Fredericksen   +4 more
doaj   +1 more source

Antiviral Activity of Selected Lamiaceae Essential Oils and Their Monoterpenes Against SARS-Cov-2

Frontiers in Pharmacology, 2022
This study presents the very first report on the in vitro antiviral activity of selected essential oils of Lamiaceae plant species and their monoterpenes against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
Sanja Ćavar Zeljković, Sanja Ćavar Zeljković, Ermin Schadich, Petr Džubák, Petr Džubák, Marián Hajdúch, Marián Hajdúch, Petr Tarkowski, Petr Tarkowski   +8 more
doaj   +1 more source

Potent single-domain antibodies that arrest respiratory syncytial virus fusion protein in its prefusion state [PDF]

, 2017
Human respiratory syncytial virus (RSV) is the main cause of lower respiratory tract infections in young children. The RSV fusion protein (F) is highly conserved and is the only viral membrane protein that is essential for infection.
Chen, Man, Gilman, Morgan SA, Graham, Barney S, Kabeche, Stephanie C, Kanekiyo, Masaru, Mas, Vicente, McLellan, Jason S, Melero, José A, Rossey, Iebe, Saelens, Xavier, Schepens, Bert, Sedeyn, Koen, Spitaels, Jan, Wrapp, Daniel   +13 more
core   +2 more sources

Antiviral activities of whey proteins [PDF]

Applied Microbiology and Biotechnology, 2015
Milk contains an array of proteins with useful bioactivities. Many milk proteins encompassing native or chemically modified casein, lactoferrin, alpha-lactalbumin, and beta-lactoglobulin demonstrated antiviral activities. Casein and alpha-lactalbumin gained anti-HIV activity after modification with 3-hydroxyphthalic anhydride.
Randy Chi Fai Cheung, Denis Tsz-Ming Ip, John Wong, Jiang Xia, Tzi Bun Ng, Yan Wang, David Chi Cheong Wan   +6 more
openaire   +3 more sources

The antiviral activities of TRIM proteins

Current Opinion in Microbiology, 2021
Tripartite motif (TRIM) proteins are a highly versatile family of host-cell factors that play an integral role in the mammalian defense against pathogens. TRIM proteins regulate either transcription-dependent antiviral responses such as pro-inflammatory cytokine induction, or they modulate other important cell-intrinsic defense pathways like autophagy.
Konstantin M. J. Sparrer, Michaela U. Gack, Michaela U. Gack, Lennart Koepke   +3 more
openaire   +4 more sources