Results 101 to 110 of about 193,162 (335)

Neural and Environmental Modulation of Motivation: What's the Moral Difference? [PDF]

open access: yes, 2018
Interventions that modify a person’s motivations through chemically or physically influencing the brain seem morally objectionable, at least when they are performed nonconsensually.
Douglas, Thomas
core  

Estimating within-school contact networks to understand influenza transmission [PDF]

open access: yes, 2012
Many epidemic models approximate social contact behavior by assuming random mixing within mixing groups (e.g., homes, schools and workplaces). The effect of more realistic social network structure on estimates of epidemic parameters is an open area of ...
Halloran, M. Elizabeth   +3 more
core   +3 more sources

Peptide Coacervates with Metal–Phenolic Membranes Modulate Glucose Metabolism and Enhance Cancer Immunotherapy

open access: yesAdvanced Materials, EarlyView.
Peptide coacervates encapsulated with interferon‐α and membranized with metal–phenolic networks (PC‐IFNα@MPNs) are designed to reprogram glucose competition between tumor and cytotoxic T cells. This metabolic modulation enhances immunotherapy by suppressing tumor glycolysis and boosting T cell effector function.
Xin Zheng   +17 more
wiley   +1 more source

Vitamin D, antiviral agent, and COVID-19

open access: yesMedical Journal of Dr. D.Y. Patil Vidyapeeth, 2021
Viroj Wiwanitkit
doaj   +1 more source

Tailoring Advanced Metal‐Based Nanomedicines for Adaptable Nanodynamic Disease Therapies and Theranostics

open access: yesAdvanced Materials, EarlyView.
This review summarizes recent advances in metal‐based nanomaterials (MBNs) as multifunctional platforms for next‐generation diagnostics and nanodynamic therapies (NDTs), highlighting their structural tunability, diverse therapeutic modalities, and broad biomedical applications in oncology and infectious disease control.
Qihang Ding   +11 more
wiley   +1 more source

Modeling long-term longitudinal HIV dynamics with application to an AIDS clinical study

open access: yes, 2009
A virologic marker, the number of HIV RNA copies or viral load, is currently used to evaluate antiretroviral (ARV) therapies in AIDS clinical trials. This marker can be used to assess the ARV potency of therapies, but is easily affected by drug exposures,
Huang, Yangxin, Lu, Tao
core   +1 more source

Interfacial Chemistry Control of In Situ Grown Gold Nanoparticles on Functionalized MXene Nanosheets

open access: yesAdvanced Materials Interfaces, EarlyView.
Gold nucleation on MXene is governed by interfacial oxidation, not termination density. An interface‐resolved pathway is uncovered in which Au nucleates at TiO2/TiOx, guided by local reduction at the surface; where tailored functionalization directs when and where nuclei form, enabling the formation of predictable heterostructures.
Valeriia Poliukhova   +5 more
wiley   +1 more source

Anti-HIV Activities and Mechanism of 12-O-Tricosanoylphorbol-20-acetate, a Novel Phorbol Ester from Ostodes katharinae

open access: yesMolecules, 2017
APOBEC3G is a member of the human cytidine deaminase family that restricts Vif-deficient viruses by being packaged with progeny virions and inducing the G to A mutation during the synthesis of HIV-1 viral DNA when the progeny virus infects new cells. HIV-
Huan Chen   +6 more
doaj   +1 more source

Inhibition of adenovirus serotype 14 infection by octadecyloxyethyl esters of (S)-[(3-hydroxy-2-phosphonomethoxy)propyl]- nucleosides in vitro. [PDF]

open access: yes, 2018
On September 22, 2008, a physician on Prince of Wales Island, Alaska, notified the Alaska Department of Health and Social Services (ADHSS) of an unusually high number of adult patients with recently diagnosed pneumonia (n = 10), including three persons ...
Barnard, Dale L   +8 more
core  

Personalizing HIV therapy, mission impossible? [PDF]

open access: yes, 2012
Sustained HIV suppression depends on a number of factors including therapy adherence, management of side effects, viral resistance and individual characteristics of patients and therapeutic settings.
Hentig, Nils von
core   +1 more source

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