Results 11 to 20 of about 111,478 (253)

Antiviral Agents

open access: yesMedical Clinics of North America, 1988
Potent effective antiviral drugs recently have been licensed for several viral diseases, ushering in a new era in the treatment of viral diseases. Several unique features in the process of a viral infection have been identified as target points for inhibition. The unique steps and the interfering compounds are the subject of this review.
Reines, Eric D., Gross, Peter A.
openaire   +2 more sources

Amantadine: an antiviral and antiparkinsonian agent

open access: yesVeterinární Medicína, 2001
Amantadine is an antiviral agent that specifically inhibits influenza A virus replication at a micromolar concentration. This drug is also very effective in the treatment of human Parkinson's disease.
J. Staničová   +2 more
doaj   +1 more source

Antiviral Activities of Algal-Based Sulfated Polysaccharides

open access: yesMolecules, 2022
An antiviral agent is urgently needed based on the high probability of the emergence and re-emergence of future viral disease, highlighted by the recent global COVID-19 pandemic. The emergence may be seen in the discovery of the Alpha, Beta, Gamma, Delta,
Jonathan Ardhianto Panggabean   +6 more
doaj   +1 more source

A Synthetic Bioactive Peptide Derived from the Asian Medicinal Plant Acacia catechu Binds to Dengue Virus and Inhibits Cell Entry

open access: yesViruses, 2020
Dengue virus (DENV) infection has become a critically important globally prevalent infectious disease, especially in tropical and subtropical countries.
Aussara Panya   +6 more
doaj   +1 more source

An Enantioselective Approach to 4-Substituted Proline Scaffolds: Synthesis of (S)-5-(tert-Butoxy carbonyl)-5-azaspiro[2.4]heptane-6-carboxylic Acid

open access: yesMolecules, 2020
A catalytic and enantioselective preparation of the (S)-4-methyleneproline scaffold is described. The key reaction is a one-pot double allylic alkylation of an imine analogue of glycine in the presence of a chinchonidine-derived catalyst under phase ...
Blanca López   +6 more
doaj   +1 more source

Ribonucleases as antiviral agents [PDF]

open access: yesMolecular Biology, 2014
Many ribonucleases (RNases) are able to inhibit the reproduction of viruses in infected cell cultures and laboratory animals, but the molecular mechanisms of their antiviral activity remain unclear. The review discusses the well-known RNases that possess established antiviral effects, including both intracellular RNases (RNase L, MCPIP1 protein, and ...
Ilinskaya O., Mahmud R.
openaire   +4 more sources

Mosquito-Borne Flaviviruses and Current Therapeutic Advances

open access: yesViruses, 2022
Mosquito-borne flavivirus infections affect approximately 400 million people worldwide each year and are global threats to public health. The common diseases caused by such flaviviruses include West Nile, yellow fever, dengue, Zika infection and Japanese
Xijing Qian, Zhongtian Qi
doaj   +1 more source

Multi-Omics Studies towards Novel Modulators of Influenza A Virus–Host Interaction

open access: yesViruses, 2016
Human influenza A viruses (IAVs) cause global pandemics and epidemics. These viruses evolve rapidly, making current treatment options ineffective.
Sandra Söderholm   +11 more
doaj   +1 more source

Antiviral Agents

open access: yes, 2009
Antiviral agents are drugs approved in the USA by the Food and Drug Administration (FDA) for the treatment or control of viral infections. Available antiviral agents mainly target stages in the viral life cycle. The target stages in the viral life cycle are; viral attachment to host cell, uncoating, synthesis of viral mRNA, translation of mRNA ...
Paintsil, E., Cheng, Yung-Chi
openaire   +2 more sources

Cardiovascular risk in chronic hepatitis B patients treated with tenofovir disoproxil fumarate or tenofovir alafenamide [PDF]

open access: yesClinical and Molecular Hepatology
Background/Aims Tenofovir disoproxil fumarate (TDF) is known to have a lipid-lowering effect. This is in contrast to tenofovir alafenamide (TAF), which has a lipid-neutral effect.
Hyeyeon Hong   +7 more
doaj   +1 more source

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