Results 191 to 200 of about 175,615 (253)

A multiplex interactome of Ebola virus proteins reveals TM9SF2 as a cell‐surface attachment factor that promotes viral entry

iMetaOmics, EarlyView.
This study generates a comprehensive Ebola virus (EBOV)‐human protein–protein interactome, comprising 1728 core high‐confidence interactions. Further interactome analysis revealed the potential association of EBOV glycoprotein (GP) with the host factor TM9SF2. Subsequent mechanistic investigations confirmed that TM9SF2 functions as an attachment factor
Limin Shang, Shouwen Du, Yuchen Liu, Letian Li, Xi Wu, Yanzhi Yuan, Chaozhi Jin, Qingkun Mi, Yuhang Wang, Xiaoshuang Shi, Jiamin Wang, Guoqing Zhang, Yidan Ma, Weijin Huang, Jigang Wang, Jian Wang, Chang Li   +16 more
wiley   +1 more source

N-alkylation of amines for the synthesis of potential antiviral agents: A structural modification approach. [PDF]

Heliyon
Arrousse N, Berdimurodov E, Bogacheva M, Zakham F, Esslali S, El Kadiri S, Taleb M, Vapalahti O.   +7 more
europepmc   +1 more source

The T‐Cell Response Mechanism in Human Papillomavirus‐Associated Cervical Cancer and New Strategies for Immunotherapy

iNew Medicine, EarlyView.
ABSTRACT Human papillomavirus (HPV) is a double‐stranded DNA virus that infects human skin and mucosal tissues exclusively. The German scientist Harald zur Hausen was awarded the 2008 Nobel Prize in Physiology or Medicine for his discovery of the link between HPV infection and cervical cancer.
Fang Zhu, Farah Nazir, Ying Zhou, Yuhua Shang, Hongliang He, Tengchuan Jin   +5 more
wiley   +1 more source

The precipitate structure of copper-based antibacterial and antiviral agents enhances their longevity for kitchen use. [PDF]

NPJ Sci Food
Nishimura T, Hashimoto M, Yamada K, Iwata R, Tateda K.   +4 more
europepmc   +1 more source

Molecular biophysics and inhibition mechanism of influenza virus A M2 viroporin by adamantane-based drugs - Challenges in designing antiviral agents. [PDF]

J Struct Biol X
Georgiou K, Kolokouris D, Kolocouris A.
europepmc   +1 more source

Comparative Effectiveness of Antiviral Agents and Monoclonal Antibodies for Early SARS-CoV-2 Therapy in Immunocompromised Patients: A Multicenter Retrospective Cohort Study (March 2021-March 2022). [PDF]

Microorganisms
Vita S, Maffongelli G, Bartoli TA, Benvenuto D, Marocco R, Rosati S, Mazzotta V, Del Borgo C, Mastrorosa I, De Marco P, D'Abramo A, Maggi F, Antinori A, Lichtner M, Nicastri E, Group C.   +15 more
europepmc   +1 more source

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Antiviral Agents

Science, 1983
Amantadine is well established as the preferred antiviral agent for the prophylaxis of influenza A and may also be beneficial therapeutically when used early in the course of the disease. Idoxuridine is applicable only in the treatment of herpetic keratitis.
T A, Krenitsky, L, Beauchamp
  +8 more sources

ANTIVIRAL AGENTS

Dermatologic Clinics, 2001
The potential severity of many viral infections and the lack of appropriate treatment for these diseases have been a source of endless frustration and helplessness for clinicians. The newly developed field of antiviral therapy is expanding at an astounding rate, with new discoveries each day.
T J, Brown, M, Vander Straten, S K, Tyring   +2 more
openaire   +2 more sources

ANTIVIRAL AGENTS

Obstetrics and Gynecology Clinics of North America, 1992
Antiviral agents are less numerous and often more toxic than antibacterial agents. Acyclovir is commonly used for suppression and treatment of recurrent genital herpes simplex virus and may be indicated for pregnant women with disseminated herpes. Zidovudine is indicated for pregnant women with human immunodeficiency virus infection who have low CD4 ...
openaire   +4 more sources