The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT This study developed a non‐invasive model using PIVKA‐II and MRI features to predict microvascular invasion in hepatocellular carcinoma, providing a reliable tool for early risk assessment and personalized treatment planning. The study included 98 patients with pathologically confirmed HCC (Child‐Pugh A, BCLC stage A), comprising 43 MVI ...
Di Gao, Rui‐Qi Jin, Hong‐Wei Wang
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Benzimidazole-Triazole Hybrids as Antimicrobial and Antiviral Agents
, 2023 Marinescu M.
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Molecular biophysics and inhibition mechanism of influenza virus A M2 viroporin by adamantane-based drugs - Challenges in designing antiviral agents. [PDF]
J Struct Biol XGeorgiou K, Kolokouris D, Kolocouris A.
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Macromolecular Materials and Engineering, EarlyView.Two novel bio‐based epoxy monomers, diglycidyl‐4‐allylphenol (DG‐4A) and triglycidyl‐diallylphenol (TG‐DA), derived from estragole (92% and 72% bio‐content), were synthesized and cured with isophorone diamin (IPDA) and 4,4´‐diaminodiphenyl sulfone (DDS). The resins show high Tgs, with DG‐4A reaching and TG‐DA exceeding DGEBA‐based systems. These resins
Florian Bauer +4 more
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Active Learning for the Discovery of Antiviral Polymers
Macromolecular Rapid Communications, EarlyView.Machine learning and active learning are integrated to accelerate the discovery of antiviral polymers. Molecular descriptors derived from polymer composition enable predictive modeling of antiviral activity, while unsupervised clustering explores chemical diversity. The active learning workflow identifies optimal candidates for synthesis, demonstrating
Clodagh M Boland +2 more
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Investigation of the long-term effects of high-potency antiviral agents on aspartate aminotransferase-to-platelet ratio index and fibrosis index based on four factors: five-year outcomes in hepatitis B e-antigen-negative chronic hepatitis B patients. [PDF]
Rev Assoc Med Bras (1992)Arslan M, Cavnar AM, Çetin Ş.
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Medicinal Research Reviews, EarlyView.ABSTRACT Respiratory syncytial virus (RSV) is a common virus that causes respiratory infections, posing a serious threat, particularly to infants, the elderly, and individuals with compromised immune systems. As the leading cause of lower respiratory tract infections (LRTIs) in infants, RSV is responsible for millions of cases worldwide each year.
Jie Shi +6 more
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Chronic Hepatitis C Infection Treated with Direct-Acting Antiviral Agents and Occurrence/Recurrence of Hepatocellular Carcinoma: Does It Still Matter? [PDF]
VirusesSmirne C +17 more
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Naval Research Logistics (NRL), EarlyView.ABSTRACT This paper examines the impacts of Volume‐Based Procurement (VBP) policies on pharmaceutical supply chains, with a focus on the strategic behaviors of manufacturers. VBP aims to reduce costs and stabilize supplies by centralizing procurement through competition based on volumes and prices.
Nani Zhou, Tong Wang, Guohua Wan
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Exploring the potential of some natural indoles as antiviral agents: quantum chemical analysis, inverse molecular docking, and affinity calculations. [PDF]
Front ChemBelal A +10 more
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