Results 341 to 350 of about 3,701,075 (393)
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HEPATOTOXICITY OF ANTIVIRAL AGENTS
Gastroenterology Clinics of North America, 1995Because most therapeutic agents used for viral infections are relatively new, experience with their adverse effects is still evolving. Hepatic toxicity has not been among the most important concerns with this class of drugs so far. Liver damage has been increasingly noted with accumulating experience, especially with antiretroviral drugs and those used
B, Styrt, J P, Freiman
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Small-molecule antiviral agents in ongoing clinical trials for COVID-19.
Current Drug Targets, 2021The coronavirus disease 2019 (COVID-19) pandemic, due to the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), emerged in December 2019 and has rapidly spread globally.
Çağla Begüm Apaydın +2 more
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The Indian Journal of Pediatrics, 2006
During the last three decades, a better understanding of viral replication and disease states caused by viral infections have led to the development of newer antiviral agents with enhanced activity and better tolerability. This review focuses on newer systemic and topical antiviral agents that are used in treatment of herpes viruses including herpes ...
Nahed, Abdel-Haq +3 more
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During the last three decades, a better understanding of viral replication and disease states caused by viral infections have led to the development of newer antiviral agents with enhanced activity and better tolerability. This review focuses on newer systemic and topical antiviral agents that are used in treatment of herpes viruses including herpes ...
Nahed, Abdel-Haq +3 more
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Amino Acid and Peptide‐Based Antiviral Agents
ChemMedChem, 2021A significant number of antiviral agents used in clinical practice are amino acids, short peptides, or peptidomimetics. Among them, several HIV protease inhibitors (e. g. lopinavir, atazanavir), HCV protease inhibitors (e. g.
Andrzej S. Skwarecki +2 more
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Obstetrics and Gynecology Clinics of North America, 1992
Antiviral agents are less numerous and often more toxic than antibacterial agents. Acyclovir is commonly used for suppression and treatment of recurrent genital herpes simplex virus and may be indicated for pregnant women with disseminated herpes. Zidovudine is indicated for pregnant women with human immunodeficiency virus infection who have low CD4 ...
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Antiviral agents are less numerous and often more toxic than antibacterial agents. Acyclovir is commonly used for suppression and treatment of recurrent genital herpes simplex virus and may be indicated for pregnant women with disseminated herpes. Zidovudine is indicated for pregnant women with human immunodeficiency virus infection who have low CD4 ...
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Annual Review of Microbiology, 1979
INTRODUCTION . . 335 DISEASE PREVALENCE AND MARKET POTENTIAL .. . . ........ 336 DEVELOPMENT COST ... . . . . ..... . . . ..... . .. . . . . ....... . . . . ..... ........ . . . ... ...... . . . . . ... ........ . .. . 339 STRATEGY AND TACTICS ........ . . ......... ... . . . .. . . . ... ......... 340 LABORATORY MODELS ... . . . . .
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INTRODUCTION . . 335 DISEASE PREVALENCE AND MARKET POTENTIAL .. . . ........ 336 DEVELOPMENT COST ... . . . . ..... . . . ..... . .. . . . . ....... . . . . ..... ........ . . . ... ...... . . . . . ... ........ . .. . 339 STRATEGY AND TACTICS ........ . . ......... ... . . . .. . . . ... ......... 340 LABORATORY MODELS ... . . . . .
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Thiazole Compounds as Antiviral Agents: An Update.
Medicinal chemistry, 2020BACKGROUND Thiazole is a wonder nucleus owing to its various pharmaceutical applications. Thiazole containing compounds (thiazoles) have shown various biological activities like antioxidant, analgesic, antibacterial, anticancer, antiallergic ...
I. Singh, Shiv K. Gupta, Sanjay Kumar
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Ophthalmology, 1985
Recent evidence indicates that many of the characteristics of herpes simplex virus (HSV) ocular disease are determined by the genome of the virus strain. The type and severity of epithelial disease, as well as the morphology of the lesions, have been demonstrated to be genetically controlled, and the region of the viral DNA responsible for these ...
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Recent evidence indicates that many of the characteristics of herpes simplex virus (HSV) ocular disease are determined by the genome of the virus strain. The type and severity of epithelial disease, as well as the morphology of the lesions, have been demonstrated to be genetically controlled, and the region of the viral DNA responsible for these ...
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1,2,3-triazole derivatives as antiviral agents
Medicinal Chemistry Research, 2023Naima Agouram
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