Results 121 to 130 of about 4,215,496 (299)

Real-world effectiveness and safety of oral azvudine versus Paxlovid in patients with COVID-19 and pre-existing hypertension: a multicentre, retrospective, cohort study in Henan Province, China

BMJ Open
Objectives Azvudine and Paxlovid are the primary antiviral agents for the management of COVID-19. However, there is currently insufficient evidence regarding the effectiveness and safety of these drugs in treating COVID-19 patients with pre-existing ...
Ling Wang, Zhigang Ren, Xiaoli Jin, Hong Luo, Donghua Zhang, Ming Cheng, Fuwei Wang, Bohan Jia, Guotao Li, Mengzhao Yang, Guangming Li, Shixi Zhang, Guowu Qian, Silin Li, Hongxia Liang   +14 more
doaj   +1 more source

The Development of the Antiviral Drug RC 28 from Rozites caperata (Pers.: Fr.) P. Karst. (Agaricomycetideae) [PDF]

, 2005
Frank F. Pirano
openalex   +1 more source

Antiviral effectiveness and safety of azvudine in hospitalized SARS‐CoV‐2 patients with pre‐existing chronic respiratory diseases: A multicenter, retrospective cohort study

View
Although azvudine has become a priority in the treatment of SARS‐CoV‐2, its effectiveness and safety among COVID‐19 patients who already have chronic respiratory diseases (CRDs) have not been sufficiently validated.
Junyi Sun, Mengzhao Yang, Daoke Yao, Yongjian Zhou, Xiaobo Hu, Guowu Qian, Yiqiang Yuan, Silin Li, Hong Luo, Shixi Zhang, Guangming Li, Donghua Zhang, Guotao Li, Yanyang Zhang, Xinjun Hu, Zujiang Yu, Guangying Cui, Zhigang Ren   +17 more
doaj   +1 more source

Research on the bio-distribution of interferon gamma-containing pharmacocytes [PDF]

, 2014
Viral hepatitis B and C- is a widespread infectious disease of the liver and is a potential threat to human life. Treatment of HCV and HBV requires prolonged (parenteral or oral) administration of antiviral and immune-stimulating agents, which often ...
Askarova, Sholpan, Ibrasheva, D., Idrissova, D., Masoud, A., Umbayev, B.   +4 more
core  

Disruption of Spike Priming in Virus Entry: Tetrandrine as a Pan‐Coronavirus Inhibitor

MedComm
The emergence of novel and highly transmissible coronavirus (CoVs) highlights the urgent need for broad‐spectrum antiviral agents. In our pursuit of effective treatments for coronavirus, we identified tetrandrine, the traditional Chinese medicine, as a ...
Kun Wang, Huiqiang Wang, Shuo Wu, Ge Yang, Haiyan Yan, Lijun Qiao, Xingqiong Li, Mengyuan Wu, Jiandong Jiang, Yuhuan Li   +9 more
doaj   +1 more source

The Advent Of Cytomegalovirus Infection In HIV Infected Patients: A review [PDF]

, 2004
Cytomegalovirus is considered as one among the long list of latent infections in humans that although normally controlled by the cellular immune response, gets activated after HIV infection takes its role on infecting the T4 lymphocytes. Clinical disease
Kirubakaran Isaac, Dr Sundar
core   +1 more source

A dynamic Bayesian nonlinear mixed-effects model of HIV response incorporating medication adherence, drug resistance and covariates

, 2011
HIV dynamic studies have contributed significantly to the understanding of HIV pathogenesis and antiviral treatment strategies for AIDS patients. Establishing the relationship of virologic responses with clinical factors and covariates during long-term ...
Acosta, Edward P., Holden-Wiltse, Jeanne, Huang, Yangxin, Wu, Hulin   +3 more
core   +1 more source

Predicting commercially available antiviral drugs that may act on the novel coronavirus (SARS-CoV-2) through a drug-target interaction deep learning model

Computational and Structural Biotechnology Journal, 2020
B. Beck, Bonggun Shin, Yoonjung Choi, Sungsoo Park, Keunsoo Kang   +4 more
semanticscholar   +1 more source

Alterations in the oral microbiome detected during long-term follow-up of COVID-19 recovered patients

Journal of Infection and Public Health
Background: The oral biome was significantly altered in COVID-19 patients, but there is still a gap in long-term follow-up studies of the oral microbiota of recovering patients.
Qiong Wang, Feng Gao, Di Zhu, Hongyan Ren, Yakun Xu, Mengmeng Lou, Chunjie Fei, Xin Xu, Zujiang Yu, Zhigang Ren   +9 more
doaj   +1 more source

Effectiveness and Safety of Oral Azvudine for Elderly Hospitalized Patients With COVID‐19: A Multicenter, Retrospective, Real‐World Study

Advanced Science
Azvudine is recommended as a priority treatment for patients with Coronavirus Disease 2019 (COVID‐19) during Omicron wave in China, but its efficacy and safety in elderly patients is unknown.
Ranran Sun, Haiyu Wang, Junyi Sun, Mengzhao Yang, Shixi Zhang, Xinjun Hu, Bo Yu, Zhan Song, Na Han, Hong Luo, Ming Cheng, Guangming Li, Guotao Li, Yiqiang Yuan, Lili Liang, Yanyang Zhang, Donghua Zhang, Silin Li, Quancheng Kan, Hongxia Liang, Zhigang Ren   +20 more
doaj   +1 more source