Results 311 to 320 of about 4,144,524 (396)

Future destinations: how people cured of hepatitis C using direct acting antiviral drugs progress in a new HCV-free world. A thematic analysis. [PDF]

Harm Reduct J
Donaldson SR, Radley A, Dillon JF.
europepmc   +1 more source

Recent Advances in Isatin–Thiazole Hybrids: Synthesis, Structural Design, and Biological Application

Chemistry &Biodiversity, EarlyView.
ABSTRACT Isatin–thiazole hybrids are considered privileged chemical scaffolds due to their broad spectrum of pharmacological properties, making them attractive candidates for drug development. As a result, isatin–thiazole derivatives have emerged as a prominent class of hybrid heterocycles and have been the focus of extensive research in recent years ...
Isadora M. G. Andrade, Edson de O. Lima Filho, Caio F. Valadão, Luana da S. M. Forezi, Fernando de C. da Silva   +4 more
wiley   +1 more source

Extrahepatic malignancies and antiviral drugs for chronic hepatitis B: A nationwide cohort study. [PDF]

Clin Mol Hepatol
Hur MH, Lee DH, Lee JH, Kim MS, Park J, Shin H, Chung SW, Cho HJ, Park MK, Jang H, Lee YB, Yu SJ, Lee SH, Jung YJ, Kim YJ, Yoon JH.   +15 more
europepmc   +1 more source

Rosemary Essential Oil Microemulsion for Fungal Keratitis Treatment

Chemistry &Biodiversity, EarlyView.
ABSTRACT This study investigated the use of Rosmarinus officinalis (rosemary) essential oil in a microemulsion (ME) formulation for the treatment of ocular fungal keratitis, a serious infection that can lead to blindness. The ME was characterized in terms of pH, stability, homogeneity, osmolarity, and other physicochemical properties.
Saulo Ribeiro, Mariana Coelho Moraes, Denise de Oliveira Scoaris, Jovita Eugênia Gazinelli Cruz Madeira, Silvia Ligório Fialho, Carolina Paula de Souza Moreira   +5 more
wiley   +1 more source

Feline Adenovirus Isolate Shows Silent Nucleotide Alterations, Alternative Receptor/Coreceptor Binding, High Resistance to Disinfectants and Antiviral Drugs, as Well as Immunomodulation. [PDF]

Animals (Basel)
Tarcsai KR, Bányai K, Bali K, Abbas AA, Kövesdi V, Ongrádi J.   +5 more
europepmc   +1 more source

Bioactivity Profiles of Progressively Ring‐Fluorinated Cyclohexyl Motifs in the WKYMVm Peptide as Formylpeptide FPR2 Agonists and in Keto‐Piperazines as Antitrypanosome Agents

ChemBioChem, EarlyView.
All‐cis‐fluorinated cyclohexyl motifs with progressively increasing levels of fluorine are introduced into the WKYMVm peptide and a class of keto‐piperazine derivatives and assayed against the FPR2 receptor or the parasite Trypanosoma brucei, respectively.
Mengfan He, Christina M. Thomson, Dawn Thompson, Vytautus Kuodis, Terry K. Smith, Sergio Dall’Angelo, David O’Hagan   +6 more
wiley   +1 more source

Long-Term Outcomes of Patients with Liver Cirrhosis After Eradication of Chronic Hepatitis C with Direct-Acting Antiviral Drugs (DAAs). [PDF]

J Hepatocell Carcinoma
Salama M, Darwesh N, Elsabaawy MM, Abdelsameea E, Gomaa A, Sabry A.   +5 more
europepmc   +1 more source

Glycosaminoglycans as Polyelectrolytes: Charge, Interactions, and Applications

ChemBioChem, EarlyView.
Glycosaminoglycans (GAGs) are linear, anionic biopolymers with their functions tightly linked to their charge. This review approaches GAGs from a polyelectrolyte perspective, shedding light on how the distribution of sulfate groups and, thus, negative charges, governs their interactions with other biomolecules.
Gergo Peter Szekeres, Eunjin Moon, Johanna K. Elter, Bryce Roper, Jayachandran Narayanan Nair Kizhakkedathu, Matthias Ballauff, Rainer Haag, Kevin Pagel   +7 more
wiley   +1 more source

Changes in Vascular Endothelial Growth Factor and Development of Hepatocellular Carcinoma in Direct-Acting Antiviral Drugs (DAAs)-Treated Hepatitis C Virus (HCV) Patients. [PDF]

Cureus
Hassan AM, Orabi HH, Abdel-Gawad M, Mohamed O, Sawy SS, Abdelmeguid MM, Bashir MA, Abdelrazzak E, Ead K, Haridy MA.   +9 more
europepmc   +1 more source

Biocompatible Chemistry: A Plug‐and‐Play Toolbox for Chemical Biology Research

ChemBioChem, EarlyView.
The “plug‐and‐play” nature of biocompatible chemistry makes it a powerful toolbox for investigating complicated biological systems and producing drug leads for clinical usages. This review summarizes the commonly used biocompatible reactions and the recent advances of their representative applications in chemical biology research, thus highlighting the
Adam R. Lovato, Zeng Lin, Qingfei Zheng
wiley   +1 more source