Results 151 to 160 of about 307,568 (303)
The 3‐Hit Metabolic Signaling Model for Autism Spectrum Disorder: A Summary
Autism Research, EarlyView.ABSTRACT Autism spectrum disorder (ASD) is a highly heritable yet environmentally sensitive neurodevelopmental condition whose biological heterogeneity has resisted a unifying causal explanation for over 100 years. The 3‐hit metabolic signaling model proposes that ASD arises from abnormal persistence of an evolutionarily conserved stress‐response ...
Robert K. Naviaux
wiley +1 more source
Hepatology, EarlyView., 2022 Lrat+ quiescent hepatic stellate cells (qHSC) give rise to Lrat+Fbln2+ activated HSC (aHSC) in alcohol‐associated hepatitis and this subpopulation is highly profibrotic, inflammatory, and immunoregulatory based on their single cell transcriptomic profile. Abstract Background and Aims Relative roles of HSCs and portal fibroblasts in alcoholic hepatitis (
Steven Balog +12 more
wiley +1 more source
A New Era for Using Natural Pigments: The Case of the C50 Carotenoid Called Bacterioruberin
Biotechnology and Applied Biochemistry, EarlyView.ABSTRACT Haloarchaea are extremophilic microorganisms belonging to the Archaea domain that require high salt concentrations to live, thus inhabiting ecosystems like salty ponds, salty marshes, or extremely salty lagoons. They are more abundant and widely distributed worldwide than initially expected.
Micaela Giani +5 more
wiley +1 more source
Biotechnology and Applied Biochemistry, EarlyView.ABSTRACT Gastrointestinal cancers (GICs) constitute one of the leading causes of cancer‐related morbidity and mortality worldwide. Despite currently available therapeutic strategies, new approaches and procedures are needed for their prevention and treatment.
Raúl Vergara +5 more
wiley +1 more source
Biofuels, Bioproducts and Biorefining, EarlyView.Abstract Among the Porphyridium genus, Porphyridium marinum exhibits the highest phycoerythrin (PE) content. In this study, the metabolic trade‐off between biomass, PE, and sulfated exopolysaccharide (EPS) production was assessed under varying nitrogen and sulfur availability, light intensity, residence time, and cultivation mode.
Rosaria Tizzani +3 more
wiley +1 more source
Sarcoid-like reaction at the patient with chronic hepatitis C on a background of antiviral therapy
Российский журнал гастроэнтерологии, гепатологии, колопроктологии, 2010 The aim of publication. To present a case of sarcoid-like reaction development, induced by antiviral therapy, in patient with chronic hepatitis C, as well as the management approach for this patient.Features of clinical case.
A. V. Lapshin +4 more
doaj
British Journal of Clinical Pharmacology, EarlyView.Aims Prescribing is a complex, essential skill that doctors must acquire to practice medicine safely and effectively. The British Pharmacological Society has historically provided a core curriculum to guide clinical pharmacology and prescribing education in UK medical schools.
Dagan O. Lonsdale +5 more
wiley +1 more source
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1984 openaire +3 more sources
British Journal of Clinical Pharmacology, EarlyView.While providing potentially life‐saving cardiorespiratory support for critically ill patients, extracorporeal membrane oxygenation (ECMO) may detrimentally affect pharmacokinetic (PK) performance and concurrent drug efficacy and safety. We describe a patient with Pneumocystis jirovecii pneumonia (PJP) in the context of acquired immunodeficiency ...
Tom C. Zwart +7 more
wiley +1 more source
British Journal of Clinical Pharmacology, EarlyView.Aims The repurposed use of favipiravir in COVID‐19 has been reported to have limited clinical efficacy, yet it has been widely used in some countries. Favipiravir causes mutagenesis in RNA viruses, and it is currently unknown whether it may have a measurable effect on the virus in humans.
Akosua A. Agyeman +9 more
wiley +1 more source