Results 41 to 50 of about 4,641 (279)

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

JESTIANALYSIS OF CICERO'S ORATIO IN CATILINAM PRIMA FROM THE ASPECT OF PHONOSTYLISTICS AND LEXICOSTYLISTICS

open access: yesHuman Research in Rehabilitation, 2013
This work represents an analysis of Cicero's speech Oratio in Catilinam Prima on two levels: phonostylistic and lexicostylistic with the goal to represent expressive voice function and figures of speech on phonostylistic level and to represent lexic ...
Sanja Merzić
doaj   +2 more sources

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Tacit Knowledge and Its Antonyms

open access: yesPhilosophia Scientiæ, 2013
Harry Collins’s Tacit and Explicit Knowledge characterises tacit knowledge through a number of antonyms: explicit, explicable, and then explicable via elaboration, transformation, mechanization and explanation and, most fundamentally, what can be ...
Tim Thornton
doaj   +1 more source

On the Analogical Suffixation of Paired Antonyms: The Case of English innie and outie

open access: yesAtlantis, 2020
In English, there are a series of paired antonyms ending with the same suffix, particularly in slang or colloquial speech—stardom, regulardom/unknowndom; friendship, enemyship; singlehood, marriedhood, etc.
Jose A. Sánchez Fajardo
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Boxer Pants, G-String, Stockings and You Know What Gear: Towards Lexical Fields Aided Vocabulary Instruction

open access: yesStyles of Communication, 2018
The major objective set to this paper is to investigate the problem of how lexical fields may be applied in vocabulary teaching at various proficiency levels of formal education, namely the primary and secondary school.
Grzegorz A. Kleparski, Anna Borkowska
doaj  

Is Black Always the Opposite of White? An Investigation on the Comprehension of Antonyms in People with Schizophrenia and in Healthy Participants

open access: yesBehavioral Sciences, 2015
The present investigation sought to expand our understanding of the cognitive processes underlying the recognition of antonyms and to evaluate whether these processes differed in patients with schizophrenia and in healthy controls.
Cristina Cacciari   +6 more
doaj   +1 more source

METHODOLOGICAL POSSIBILITIES IN ANTONYMS

open access: yes, 2023
The article scientifically substantiates the linguistic and colloquial phenomena of antonyms and their stylistic features in Uzbek linguistics. The issue of scientific research carried out by various scientists within the framework of language levels ...
F.Mizomova
core   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

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