Results 51 to 60 of about 4,724 (299)

Tacit Knowledge and Its Antonyms

open access: yesPhilosophia Scientiæ, 2013
Harry Collins’s Tacit and Explicit Knowledge characterises tacit knowledge through a number of antonyms: explicit, explicable, and then explicable via elaboration, transformation, mechanization and explanation and, most fundamentally, what can be ...
Tim Thornton
doaj   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

open access: yesFEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana   +3 more
wiley   +1 more source

Arap Dilinde Ezdad Kavramı

open access: yesEskiyeni, 2016
Ezdadın anlamı, birbirinin zıddı olan iki kelime için aynı sözcüğün kullanılmasıdır. Bu konu, hicri ikinci asrın sonlarından itibaren, Arap dilinin gelişim sürecinde, dilbi- limciler tarafından en fazla tartışılan konulardan birisidir. Bu çalışmada önce,
Zeynep Arkan
doaj  

Scalar alternative activation for implicature processing: a lexical decision study with antonyms and negation

open access: yesLanguage and Cognition
Scalar words such as warm may give rise to inferences such as warm but not hot. Under standard accounts, such scalar implicatures are derived by negating stronger alternatives.
Radim Lacina   +3 more
doaj   +1 more source

Is Black Always the Opposite of White? An Investigation on the Comprehension of Antonyms in People with Schizophrenia and in Healthy Participants

open access: yesBehavioral Sciences, 2015
The present investigation sought to expand our understanding of the cognitive processes underlying the recognition of antonyms and to evaluate whether these processes differed in patients with schizophrenia and in healthy controls.
Cristina Cacciari   +6 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

SYNONYMS AND ANTONYMS

open access: yesNotes and Queries
This article explores the importance of synonyms and antonyms in English language learning. It emphasizes how these elements enhance students’ vocabulary, comprehension, and expressive abilities. The article also discusses modern teaching approaches, digital tools, and assessment methods used in language education.
openaire   +3 more sources

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Antonyms in 19th-Century Prose: Quantitative Analysis and Its Idiostylistic Interpretation

open access: yesИзвестия Уральского федерального университета. Серия 2: Гуманитарные науки
This article explores the use of corpora to identify characteristic and individual authorial peculiarities in the use of antonyms in nineteenth-century prose, based on sources such as major antonym dictionaries and corpora for texts by A. P.
Mikhail Yurievich Mukhin
doaj   +1 more source

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