Results 91 to 100 of about 1,446 (177)
Abstract Introduction Pulmonary arterial hypertension secondary to congenital heart disease (CHD-PAH) with systemic-to-pulmonary shunt is characterized by proliferative vascular remodeling. Excessive proliferation and resistance to apoptosis of pulmonary artery smooth muscle cells (PASMCs) are the ...
X Y Liu +7 more
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(A) CD31 immunostaining (brown color) of three-month-old reproductive tracts reveal atypical/open blood vessels (arrows) throughout the Antxr2−/− uterus and cervix. Boxed areas are blown up to highlight vasculature.
Claire V. Reeves (172057) +6 more
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Increased collagen and fibronectin content in aged nulliparous Antxr2−/− uterine tissue.
(A) Immunofluorescent staining of uterine tissue isolated from six-month-old mice demonstrated increased type I collagen, type IV collagen and fibronectin deposition in the Antxr2−/− tissue. DAPI (blue) was used for nuclear staining.
Claire V. Reeves (172057) +6 more
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Original Article Anthrax toxin receptor 2 gene (ANTXR2) rs4333130 is associated with ankylosing spondylitis [PDF]
: Results of recent published studies on the association between the ANTXR2 rs4333130 polymorphism and the risk of ankylosing spondylitis (AS) have often been conflicting.
Yanjuan Ou
core
PAD683N and PAD683K Bind and Support Intoxication via ANTXR2
CHO-R1.1 cells stably expressing human ANTXR2-EGFP (A), human ANTXR1-EGFP (B), and control CHO-R1.1 cells expressing no receptors (C) were analyzed by flow cytometry after incubation with 100 nM purified PA or PAD683K proteins, followed by an anti-PA ...
Darran J Wigelsworth (21911) +8 more
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Differential expression of anthrax toxin receptor 2 in cancers of the breast.
Breast cancer affects women at relatively high frequency (1). We mined published microarray datasets (2, 3) to determine in an unbiased fashion and at the systems level genes most differentially expressed in the primary tumors of patients with breast ...
Shahan Mamoor
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Characterizing the Biomechanical and Biochemical Properties of Mouse Uterine Tissue [PDF]
For a successful pregnancy, the uterus and the cervix work together as a biomechanical structure to protect the fetus until term. During gestation, typically 37 weeks, the uterus undergoes a growth transformation to accommodate the growing fetus and to ...
Yoshida, Kyoko +2 more
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Infantile Systemic Hyalinosis: A Case Report with a Novel Mutation
Infantile Systemic Hyalinosis (ISH) (OMIM 236490) is a rare, progressive and fatal autosomal recessive disorder characterized by multiple subcutaneous skin nodules, gingival hypertrophy, osteopenia, joint contractures, failure to thrive, diarrhea with ...
Siham Al Sinani +2 more
doaj
ANTXR2 is differentially expressed in glioblastoma.
Glioblastoma is difficult to treat and patients are often provided poor prognosis (1), indicating a requirement for therapeutic target identification and drug development. Differentially expressed genes represent by definition among the most promising targets for the development of novel chemotherapies (2, 3).
openaire +1 more source
The residues C255/C279 and C230/C315 form two disulfide bonds in the Ig domain of ANTXR2.
A. In the ANTXR2 ectodomain (residues 38–318), C255/C279 and C230/C315 form two disulfide bonds in the Ig domain (residues 219–318). B. The purified TF-R318 and the C/A mutants of TF-R318 as indicated were run in SDS-PAGE, stained by Coomassie blue.
Jens Puschhof (759973) +12 more
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